The production of nominal and verbal inflection in an agglutinative language: evidence from Hungarian

The contrast between regular and irregular inflectional morphology has been useful in investigating the functional and neural architecture of language. However, most studies have examined the regular/irregular distinction in non-agglutinative Indo-European languages (primarily English) with relatively simple morphology. Additionally, the majority of research has focused on verbal rather than nominal inflectional morphology. The present study attempts to address these gaps by introducing both plural and past tense production tasks in Hungarian, an agglutinative non-Indo-European language with complex morphology. Here we report results on these tasks from healthy Hungarian native-speaking adults, in whom we examine regular and irregular nominal and verbal inflection in a within-subjects design. Regular and irregular nouns and verbs were stem on frequency, word length and phonological structure, and both accuracy and response times were acquired. The results revealed that the regular/irregular contrast yields similar patterns in Hungarian, for both nominal and verbal inflection, as in previous studies of non-agglutinative Indo-European languages: the production of irregular inflected forms was both less accurate and slower than of regular forms, both for plural and past-tense inflection. The results replicate and extend previous findings to an agglutinative language with complex morphology. Together with previous studies, the evidence suggests that the regular/irregular distinction yields a basic behavioral pattern that holds across language families and linguistic typologies. Finally, the study sets the stage for further research examining the neurocognitive substrates of regular and irregular morphology in an agglutinative non-Indo-European language

DAF-16 and Δ9 Desaturase Genes Promote Cold Tolerance in Long-Lived Caenorhabditis elegans age-1 Mutants

In Caenorhabditis elegans, mutants of the conserved insulin/IGF-1 signalling (IIS) pathway are long-lived and stress resistant due to the altered expression of DAF-16 target genes such as those involved in cellular defence and metabolism. The three Δ9 desaturase genes, fat-5, fat-6 and fat-7, are included amongst these DAF-16 targets, and it is well established that Δ9 desaturase enzymes play an important role in survival at low temperatures. However, no assessment of cold tolerance has previously been reported for IIS mutants. We demonstrate that long-lived age-1(hx546) mutants are remarkably resilient to low temperature stress relative to wild type worms, and that this is dependent upon daf-16. We also show that cold tolerance following direct transfer to low temperatures is increased in wild type worms during the facultative, daf-16 dependent, dauer stage. Although the cold tolerant phenotype of age-1(hx546) mutants is predominantly due to the Δ9 desaturase genes, additional transcriptional targets of DAF-16 are also involved. Surprisingly, survival of wild type adults following a rapid temperature decline is not dependent upon functional daf-16, and cellular distributions of a DAF-16::GFP fusion protein indicate that DAF-16 is not activated during low temperature stress. This suggests that cold-induced physiological defences are not specifically regulated by the IIS pathway and DAF-16, but expression of DAF-16 target genes in IIS mutants and dauers is sufficient to promote cross tolerance to low temperatures in addition to other forms of stress

Recruitment and Consolidation of Cell Assemblies for Words by Way of Hebbian Learning and Competition in a Multi-Layer Neural Network

Current cognitive theories postulate either localist representations of knowledge or fully overlapping, distributed ones. We use a connectionist model that closely replicates known anatomical properties of the cerebral cortex and neurophysiological principles to show that Hebbian learning in a multi-layer neural network leads to memory traces (cell assemblies) that are both distributed and anatomically distinct. Taking the example of word learning based on action-perception correlation, we document mechanisms underlying the emergence of these assemblies, especially (i) the recruitment of neurons and consolidation of connections defining the kernel of the assembly along with (ii) the pruning of the cell assembly’s halo (consisting of very weakly connected cells). We found that, whereas a learning rule mapping covariance led to significant overlap and merging of assemblies, a neurobiologically grounded synaptic plasticity rule with fixed LTP/LTD thresholds produced minimal overlap and prevented merging, exhibiting competitive learning behaviour. Our results are discussed in light of current theories of language and memory. As simulations with neurobiologically realistic neural networks demonstrate here spontaneous emergence of lexical representations that are both cortically dispersed and anatomically distinct, both localist and distributed cognitive accounts receive partial support

Características iniciais da comunicação verbal de pré-escolares com Alterações Específicas do Desenvolvimento da Linguagem em fala espontânea Primary characteristics of the verbal communication of preschoolers with Specific Language Impairment in spontaneous speech

OBJETIVO: Verificar desempenho fonológico de pré-escolares com Alterações Específicas do Desenvolvimento da Linguagem (AEDL) em fala espontânea. MÉTODOS: Foram sujeitos 27 crianças com AEDL, entre três anos e cinco anos e 11 meses, em tratamento fonoaudiológico. Foram selecionados aqueles que realizaram ao menos 50% da avaliação da fonologia a partir de provas de nomeação e imitação de palavras, ou que apresentaram inteligibilidade de fala passível de análise. Foram coletadas amostras de fala na prova de pragmática e no discurso eliciado por figuras. Foram realizadas análises a partir da utilização de processos fonológicos do desenvolvimento de linguagem (PD) e idiossincráticos (PI). RESULTADOS: A estatística descritiva (médias de PD e PI) indicou grande variabilidade intra-grupos. Não houve variação em número de processos conforme a idade (PD: p=0,38; PI: p=0,72), porém houve predominância de PD em todas as idades, nas duas provas aplicadas (Z=-6,327; p<0,001). A ocorrência de PD e PI foi maior na prova de pragmática (p<0,001), situação em que o número de palavras produzidas também foi maior (T-valor=8,93; p=0,000). CONCLUSÃO: A grande variabilidade intra-grupo confirma a heterogeneidade dos quadros de AEDL. Pode-se atribuir a ininteligibilidade, que dificulta a avaliação da linguagem expressiva desses sujeitos, à ocorrência de PD e PI concomitantemente. Ademais, a interação desenvolvida durante a prova de pragmática mostrou-se mais efetiva para a obtenção de amostra de fala espontânea para a análise da fonologia, além de confirmar a existência de grandes dificuldades relacionadas à elaboração de idéias e sua expressão em sujeitos com AEDL.<br>PURPOSE: To verify the phonological performance of preschoolers with Specific Language Impairment (SLI) in spontaneous speech. METHODS: The subjects were 27 children with SLI with ages between three years and five years and 11 months, who attended Speech-Language Pathology therapy. The subjects who carried out at least 50% of the phonological assessment or who had speech intelligibility that allowed analysis were selected. Speech samples were obtained from a pragmatics evaluation and from elicited discourse. Analyses considered the use of developmental (DP) and idiossyncratic phonological processes (IP) in spontaneous speech. RESULTS: The descriptive statistics (mean DP and IP) showed large within-group variability. There was no variation in the number of processes according to age (DP: p=0.38; IP: p=0.72), but there was a prevalence of DP in all ages, in both tests (Z=-6.327; p<0.001). The occurrence of DP and IP was higher in the pragmatics evaluation (p<0.001), situation in which the number of words produced was also greater (T-value=8.93; p=0.000). CONCLUSION: The great within-group variability confirms the heterogeneity of SLI. The speech unintelligibility, which hampers the assessment of the expressive language of these subjects, can be attributed to the co-occurrence of DP and IP. Moreover, the interaction during the pragmatics evaluation was more effective for obtaining a sample of spontaneous speech for phonological analysis, and confirms the existence of major difficulties related to the development of ideas and their expression in subjects with SLI

The past tense inflection project (PTIP): Speeded past tense inflections, imageability ratings, and past tense consistency measures for 2,200 verbs

10.3758/s13428-012-0240-yBehavior Research Methods451151-15