144 research outputs found
Time Interval-enhanced Graph Neural Network for Shared-account Cross-domain Sequential Recommendation
Shared-account Cross-domain Sequential Recommendation (SCSR) task aims to
recommend the next item via leveraging the mixed user behaviors in multiple
domains. It is gaining immense research attention as more and more users tend
to sign up on different platforms and share accounts with others to access
domain-specific services. Existing works on SCSR mainly rely on mining
sequential patterns via Recurrent Neural Network (RNN)-based models, which
suffer from the following limitations: 1) RNN-based methods overwhelmingly
target discovering sequential dependencies in single-user behaviors. They are
not expressive enough to capture the relationships among multiple entities in
SCSR. 2) All existing methods bridge two domains via knowledge transfer in the
latent space, and ignore the explicit cross-domain graph structure. 3) None
existing studies consider the time interval information among items, which is
essential in the sequential recommendation for characterizing different items
and learning discriminative representations for them. In this work, we propose
a new graph-based solution, namely TiDA-GCN, to address the above challenges.
Specifically, we first link users and items in each domain as a graph. Then, we
devise a domain-aware graph convolution network to learn userspecific node
representations. To fully account for users' domainspecific preferences on
items, two effective attention mechanisms are further developed to selectively
guide the message passing process. Moreover, to further enhance item- and
account-level representation learning, we incorporate the time interval into
the message passing, and design an account-aware self-attention module for
learning items' interactive characteristics. Experiments demonstrate the
superiority of our proposed method from various aspects.Comment: 15 pages, 6 figure
Simulation and Experimental Analyses on Quasi-Static and Dynamic Performances of Four-Star Cellular Structure
A novel four-star cellular structure (FSCS) is proposed. Firstly, relative density of FSCS, regular octagons and regular hexagons are obtained accordingly. Then, their in-plane quasi-static and dynamic performances are conducted under the premise of equal number of cells, equal mass and equal relative density by adopting Hyperworks and Ls-Dyna software. Macroscopic deformation processes indicate that FSCS, regular octagons and regular hexagons are presented as "compression-shrinkage" negative Poisson\u27s ratio deformation mode, "V" deformation mode and "X" deformation mode, respectively. Subsequently, size effects of unit cell are carried out, and as the number of cell layers reaches no less than 9, platform stress of FSCS gradually tends to be stable. To verify the accuracy of finite element (FE) simulation models, quasi-static compression test is executed on three-dimensional FSCS. The results indicate that FE simulation results agree well with experimental predictions, and the proposed FSCS is equipped with superior energy absorption capability
Identification of Two bZIP Transcription Factors Interacting with the Promoter of Soybean Rubisco Activase Gene (GmRCAα)
Rubisco activase (RCA), a key photosynthetic protein, catalyses the activation of Rubisco and thus plays an important role in photosynthesis. Although the RCA gene has been characterized in a variety of species, the molecular mechanism regulating its transcription remains unclear. Our previous studies on RCA gene expression in soybean suggested that expression of this gene is regulated by trans-acting factors. In the present study, we verified activity of the GmRCAα promoter in both soybean and Arabidopsis and used a yeast one-hybrid (Y1H) system for screening a leaf cDNA expression library to identify transcription factors (TFs) interacting with the GmRCAα promoter. Four basic leucine zipper (bZIP) TFs, GmbZIP04g, GmbZIP07g, GmbZIP1 and GmbZIP71, were isolated, and GmbZIP04g and GmbZIP07g were confirmed as able to bind to a 21-nt G-box-containing sequence. Additionally, the expression patterns of GmbZIP04g, GmbZIp07g and GmRCAα were analysed in response to abiotic stresses and during a 24-h period. Our study will help to advance elucidation of the network regulating GmRCAα transcription
Essential role of liquid phase on melt-processed GdBCO single-grain superconductors
RE-Ba-Cu-O (RE denotes rare earth elements) single-grain superconductors have
garnered considerable attention owning to their ability to trap strong magnetic
field and self-stability for maglev. Here, we employed a modified melt-growth
method by adding liquid source (LS) to provide a liquid rich environment during
crystal growth. It further enables a significantly low maximum processing
temperature (Tmax) even approaching peritectic decomposition temperature. This
method was referred as the liquid source rich low Tmax (LS+LTmax) growth method
which combines the advantage of Top Seeded Infiltration Growth (TSIG) into Top
Seeded Melt-texture Growth (TSMG). The LS+LTmax method synergistically
regulates the perfect appearance and high superconducting performance in REBCO
single grains. The complementary role of liquid source and low Tmax on the
crystallization has been carefully investigated. Microstructure analysis
demonstrates that the LS+LTmax processed GdBCO single grains show clear
advantages of uniform distribution of RE3+ ions as well as RE211 particles. The
inhibition of Gd211 coarsening leads to improved pining properties. GdBCO
single-grain superconductors with diameter of 18 mm and 25 mm show maximum
trapped magnetic field of 0.746 T and 1.140 T at 77 K. These trapped fields are
significantly higher than those of conventional TSMG samples. Particularly, at
grain boundaries with reduced RE211 density superior flux pinning performance
has been observed. It indicates the existence of multiple pinning mechanisms at
these areas. The presented strategy provides essential LS+LTmax technology for
processing high performance single-grain superconductors with improved
reliability which is considered important for engineering applications
The Representation of Mosuo People and Mosuo Culture in Chinese Tourism Websites
Past research has shown that because tourism itself is a product of a gendered society, its processes are gendered in terms of construction, presentation, and consumption. This study examines how these websites shape the image of the Mosuo people and the Mosuo culture by analyzing texts in Chinese tourism websites. Ten representative Chinese tourism websites were selected for this study, and all relevant texts that could be retrieved were analyzed manually. All samples selected were officially published and represent only the attitudes of the tourism websites. The results of the study show that there are a large number of feminized or sexualized descriptions in the texts about the Mosuo people and the Mosuo culture provided by Chinese tourism websites. The language used on tourism websites is shaped by discourses of patriarchy and sexuality and is intended for heterosexual male tourists
The perspectives of NETosis on the progression of obesity and obesity-related diseases: mechanisms and applications
Obesity is a disease commonly associated with urbanization and can also be characterized as a systemic, chronic metabolic condition resulting from an imbalance between energy intake and expenditure. The World Health Organization (WHO) has identified obesity as the most serious chronic disease that is increasingly prevalent in the world population. If left untreated, it can lead to dangerous health issues such as hypertension, hyperglycemia, hyperlipidemia, hyperuricemia, nonalcoholic steatohepatitis, atherosclerosis, and vulnerability to cardiovascular and cerebrovascular events. The specific mechanisms by which obesity affects the development of these diseases can be refined to the effect on immune cells. Existing studies have shown that the development of obesity and its associated diseases is closely related to the balance or lack thereof in the number and function of various immune cells, of which neutrophils are the most abundant immune cells in humans, infiltrating and accumulating in the adipose tissues of obese individuals, whereas NETosis, as a newly discovered type of neutrophil-related cell death, its role in the development of obesity and related diseases is increasingly emphasized. The article reviews the significant role that NETosis plays in the development of obesity and related diseases, such as diabetes and its complications. It discusses the epidemiology and negative impacts of obesity, explains the mechanisms of NETosis, and examines its potential as a targeted drug to treat obesity and associated ailments
Highly-stable, flexible delivery of microjoule-level ultrafast pulses in vacuumized anti-resonant hollow-core fibers for active synchronization
We demonstrate the stable and flexible light delivery of multi-{\mu}J,
sub-200-fs pulses over a ~10-m-long vacuumized anti-resonant hollow-core fiber
(AR-HCF), which was successfully used for high-performance pulse
synchronization. Compared with the pulse train launched into the AR-HCF, the
transmitted pulse train out of the fiber exhibits excellent stabilities in
pulse power and spectrum, with pointing stability largely improved. The
walk-off between the fiber-delivery and the other free-space-propagation pulse
trains, in an open loop, was measured to be <6 fs root-mean-square (RMS) over
90 minutes, corresponding to a relative optical-path variation of <2x10-7. This
walk-off can be further suppressed to ~2 fs RMS simply using an active control
loop, highlighting the great application potentials of this AR-HCF set-up in
large-scale laser and accelerator facilities
The mediating effect of resilience on mental health literacy and positive coping style among Chinese empty nesters: A cross-sectional study
ObjectivesEmpty nesters in China have limited mental health literacy (MHL), which may lead to poorer health outcomes. Studies demonstrate that MHL is associated with both resilience and positive coping style. However, the potential mechanism of MHL, resilience and positive coping style remain unclear. Therefore, the study aims to investigate the possible mediating role of resilience in the relationship between MHL and positive coping style.MethodIn this cross-sectional study, a total of 363 empty nesters from Huzhou, China were surveyed in 2022. The Chinese version of Mental Health Literacy Scale (C-MHLS), the Chinese version of 10-item Connor-Davidson Resilience Scale (CD-RISC-10) and the Simplified Coping Style Questionnaire (SCSQ-19) were used to assess MHL, resilience, and positive coping style, respectively.ResultsPositive coping style was significantly correlated with MHL and resilience, and MHL was positively correlated with resilience (p < 0.01). MHL can significantly and positively predict the positive coping style, and resilience played a partial intermediary role between MHL and positive coping style, with the intermediary effect of 77.36%.ConclusionThis study indicates that MHL not only directly affected positive coping style, but also indirectly influences positive coping style by increasing the resilience of empty nesters. The results provide an empirical evidence for the development of intervention programs to improve positive coping style directly and indirectly. Consequently, community health servicers should take targeted measures which focus on MHL and resilience as breakthrough points to stimulate positive coping style of empty nesters, and ultimately achieve their overall well-being
First identification of canine adenovirus 1 in mink and bioinformatics analysis of its 100 K protein
IntroductionAnimal trade favors the spreading of emerging canine adenovirus 1 (CAdV-1) in mink. Because the 100K protein is not exposed to the viral surface at any stage, it can be used to differentiate the vaccine from wild virus infection. However, no related research has been conducted. This study aimed to find evidence of CAdV-1 in mink and predict the character of the 100K protein in the current circulating CAdV-1 strain of mink.MethodIn this experiment, the identification of CAdV-1, the phylogenetic tree, homology, and bioinformatics analysis of 100K were conducted.ResultsThe results showed that the CAdV-1 was identified in the mink and that its Fiber was located in a separate branch. It was closely related to strains isolated from Norwegian Arctic fox and Red fox. 100K was located in a separate branch, which had the closest genetic relationship with skunks, porcupines, raccoons, and hedgehogs and a far genetic relationship with the strains in dogs. 100K protein is an unstable and hydrophobic protein. It had evidence of selective pressure and recombination, 1 glycosylation site, 48 phosphorylation sites, 60 dominant B cell epitopes, and 9 peptides of MHC-I and MHC-II. Its subcellular localization was mainly in the endoplasmic reticulum and mitochondria. The binding sites of 100K proteins were DBP proteins and 33K proteins.DiscussionThe stains in the mink were different from fox. The exploration of its genomic characteristics will provide us with a deeper understanding of the prevention of canine adenovirus
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