Irreducible MultiQutrit Correlations in Greenberger-Horne-Zeilinger Type States

Following the idea of the continuity approach in [D. L. Zhou, Phys. Rev. Lett. 101, 180505 (2008)], we obtain the degrees of irreducible multi-party correlations in two families of $n$-qutrit Greenberger-Horne-Zeilinger type states. For the pure states in one of the families, the irreducible 2-party, $n$-party and $(n-m)$-party ($0< m < n-2$) correlations are nonzero, which is different from the $n$-qubit case. We also derive the correlation distributions in the $n$-qutrit maximal slice state, which can be uniquely determined by its $(n-1)$-qutrit reduced density matrices among pure states. It is proved that there is no irreducible $n$-qutrit correlation in the maximal slice state. This enlightens us to give a discussion about how to characterize the pure states with irreducible $n$-party correlation in arbitrarily high-dimensional systems by the way of the continuity approach.Comment: 5p, no fi

Bis[(diphenyl­phosphanylmeth­yl)diphenyl­phosphane sulfide-κ2 P,S]copper(I) hexa­fluoridophosphate

In the title compound, [Cu(C25H22P2S)2]PF6, the CuI atom, lying on a twofold rotation axis, adopts a distorted tetra­hedral geometry. The (diphenyl­phosphanylmeth­yl)diphenyl­phos­phane sulfide ligand coordinates to the CuI atom through one S and one P atom, forming a stable five-membered chelate ring. The P atom of the PF6 − anion also lies on a twofold rotation axis

Cytosolic delivery of macromolecules: I. Synthesis and characterization of pH-sensitive acyloxyalkylimidazoles

A series of 1-(acyloxyalkyl)imidazoles (AAI) were synthesized by nucleophilic substitution of chloroalkyl esters of fatty acids with imidazole. The former was prepared from fatty acid chloride and an aldehyde. When incorporated into liposomes, these lipids show an apparent pK(a) value ranging from 5.12 for 1-(palmitoyloxymethyl)imidazole (PMI) to 5.29 for 1-[(alpha-myristoyloxy)ethyl]imidazole (alpha-MEI) as determined by a fluorescence assay. When the imidazole moiety was protonated, the lipids were surface-active, as demonstrated by hemolytic activity towards red blood cells. As expected, AAI were hydrolyzed in serum as well as in cell homogenate. They were significantly less toxic than biochemically stable N-dodecylimidazole (NDI) towards Chinese hamster ovary (CHO) and RAW 264.7 (RAW) cells as determined by MTT assay. When fed to RAW cells, fluorescein-labeled oligonucleotides encapsulated in liposomes containing 20 mol% 1-(stearoyloxymethyl)imidazole (SMI) resulted in punctate as well as partially diffuse fluorescence. In a functional assay involving down-regulation of luciferase in CV-1 cells, neutral liposomes containing imidazole lipids showed suboptimal delivery of antisense phosphorothioate oligomers. Taken together, the results suggest that AAI are of potential use in developing nontoxic, pH-sensitive liposomes. However, these liposomal formulations need to be optimized to achieve higher concentrations of pH-sensitive detergents within the endosome to facilitate efficient cytosolic release of liposome-entrapped contents

Chloridobis(1,2,3,4-tetra­hydro-1,4,6,11-tetra­aza­naphthacene-κN 6)copper(I)

In the title complex, [CuCl(C14H12N4)2], the CuI atom, lying on a twofold rotation axis, is coordinated by two N atoms of two 1,2,3,4-tetra­hydro-1,4,6,11-tetra­aza­naphthacene ligands and one Cl atom, also lying on the twofold rotation axis, in a distorted trigonal-planar geometry. The complex mol­ecules are connected into a one-dimensional structure along [001] via N—H⋯N hydrogen bonds and further into a three-dimensional structure via N—H⋯Cl hydrogen bonds. π–π inter­actions between the pyrazine and benzene rings and between the benzene rings [centroid–centroid distances = 3.5635 (15) and 3.9128 (16) Å] are present