The Law and Mechanism of Rockburst Occurring in Huize Lead—Zinc Mine

Rockburst is a geological disaster of dynamic equilibrium loss. According to the rock core disking and the schistose scaling on the sidewalls of cross-cut drift found in the drilling exploration of engineering geology and the site investigation in the property of Huize lead-zinc mine,the basic law of rocktburst occurring in this mine is summed up;According to the results from the site investigation and the rock mechanics tests in the laboratory,the genesis and mechanism of rockburst are analyzed to provide the important basis for selecting a reasonable deep mining method and controlling the rockburst

Identification of responsive gene modules by network-based gene clustering and extending: application to inflammation and angiogenesis

<p>Abstract</p> <p>Background</p> <p>Cell responses to environmental stimuli are usually organized as relatively separate responsive gene modules at the molecular level. Identification of responsive gene modules rather than individual differentially expressed (DE) genes will provide important information about the underlying molecular mechanisms. Most of current methods formulate module identification as an optimization problem: find the active sub-networks in the genome-wide gene network by maximizing the objective function considering the gene differential expression and/or the gene-gene co-expression information. Here we presented a new formulation of this task: a group of closely-connected and co-expressed DE genes in the gene network are regarded as the signatures of the underlying responsive gene modules; the modules can be identified by finding the signatures and then recovering the "missing parts" by adding the intermediate genes that connect the DE genes in the gene network.</p> <p>Results</p> <p>ClustEx, a two-step method based on the new formulation, was developed and applied to identify the responsive gene modules of human umbilical vein endothelial cells (HUVECs) in inflammation and angiogenesis models by integrating the time-course microarray data and genome-wide PPI data. It shows better performance than several available module identification tools by testing on the reference responsive gene sets. Gene set analysis of KEGG pathways, GO terms and microRNAs (miRNAs) target gene sets further supports the ClustEx predictions.</p> <p>Conclusion</p> <p>Taking the closely-connected and co-expressed DE genes in the condition-specific gene network as the signatures of the underlying responsive gene modules provides a new strategy to solve the module identification problem. The identified responsive gene modules of HUVECs and the corresponding enriched pathways/miRNAs provide useful resources for understanding the inflammatory and angiogenic responses of vascular systems.</p

Studying newborn neutron stars by the transient emission after stellar collapses and compact binary mergers

The formation of neutron stars (NSs), both from collapses of massive stars and mergers of compact objects, can be usually indicated by bright transients emitted from explosively-ejected material. In particular, if the newborn NSs can rotate at a millisecond period and have a sufficiently high magnetic field, then the spin-down of the NSs would provide a remarkable amount of energy to the emitting material. As a result, super-luminous supernovae could be produced in the massive stellar collapse cases, while some unusual fast evolving and luminous optical transients could arise from the cases of NS mergers and accretion-induced collapses of white dwarfs. In all cases, if the dipolar magnetic fields of the newborn NSs can be amplified to be as high as $10^{15}$ G, a relativistic jet could be launched and then a gamma-ray burst can be produced as the jet successfully breaks out from the surrounding nearly-isotropic ejected material.Comment: 10 pages, 9 pictures, to appear in the AIP Proceedings of the Xiamen-CUSTIPEN Workshop on the EOS of Dense Neutron-Rich Matter in the Era of Gravitational Wave Astronomy, Jan. 3-7, Xiamen, Chin

Bootstrap Generalization Ability from Loss Landscape Perspective

Domain generalization aims to learn a model that can generalize well on the unseen test dataset, i.e., out-of-distribution data, which has different distribution from the training dataset. To address domain generalization in computer vision, we introduce the loss landscape theory into this field. Specifically, we bootstrap the generalization ability of the deep learning model from the loss landscape perspective in four aspects, including backbone, regularization, training paradigm, and learning rate. We verify the proposed theory on the NICO++, PACS, and VLCS datasets by doing extensive ablation studies as well as visualizations. In addition, we apply this theory in the ECCV 2022 NICO Challenge1 and achieve the 3rd place without using any domain invariant methods.Comment: 18 pages, 4 figure

Adenoid cystic carcinoma of the esophagus: report of two cases and review of the Chinese literature

Squamous cell carcinoma is the major pathology type of esophageal cancer in China, where adenocarcinoma is rare and adenoid cystic carcinoma (ACC) is more rare comparing to the western countries. We report the surgical and pathologic findings of two cases of primary ACC of the esophagus, and review of the Chinese literature of this tumor. VIRTUAL SLIDES: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/150758223884324