20,139 research outputs found
Radiatively Generated Isospin Violations in the Nucleon and the NuTeV Anomaly
Predictions of isospin asymmetries of valence and sea distributions are
presented which are generated by QED leading photon
bremsstrahlung effects. Together with isospin violations arising from
nonperturbative hadronic sources (such as quark and target mass differences) as
well as with even a conservative contribution from a strangeness asymmetry
(), the discrepancy between the large NuTeV `anomaly' result for
and the world average of other measurements is removed.Comment: 10 pages, 2 figure
Constraints on spin-dependent parton distributions at large x from global QCD analysis
We investigate the behavior of spin-dependent parton distribution functions
(PDFs) at large parton momentum fractions x in the context of global QCD
analysis. We explore the constraints from existing deep-inelastic scattering
data, and from theoretical expectations for the leading x -> 1 behavior based
on hard gluon exchange in perturbative QCD. Systematic uncertainties from the
dependence of the PDFs on the choice of parametrization are studied by
considering functional forms motivated by orbital angular momentum arguments.
Finally, we quantify the reduction in the PDF uncertainties that may be
expected from future high-x data from Jefferson Lab at 12 GeV.Comment: 14 pages, 3 figures, 1 tabl
Epidermal growth factor coordinately regulates the expression of prostaglandin G/H synthase and cytosolic phospholipase A2 genes in embryonic mouse cells.
Confluent, primary cultures of mouse embryo palate mesenchyme (MEPM) cells are refractory to activation of phospholipase A2 (PLA2) by the calcium ionophore A23187. However, treatment of these cultures with epidermal growth factor (EGF) permits the cells to activate PLA2 in response to A23187. We have developed this finding by exploring molecular mechanisms by which growth factors modulate mobilization and metabolism of arachidonic acid. We found chronic treatment (\u3e 6 h) of confluent MEPM cells with EGF (a) increases their ability to metabolize exogenous arachidonic acid to prostaglandin E2 (PGE2) and (b) stimulated constitutive expression of activities of PLA2 and cyclooxygenase (CyOx). Immunoprecipitation of [35S]proteins and Western blot analysis revealed EGF treatment stimulated synthesis and accumulation of PLA2c, CyOx-1, and CyOx-2. Northern hybridization analysis revealed EGF increased the steady-state levels of a transcript for the high molecular weight, cytosolic PLA2 (PLA2c), and both the 2.8- and 4.2-kb transcripts for CyOx-1 and CyOx-2, respectively. In vitro nuclear transcription assays showed a parallel increase in the transcription rate of the genes corresponding to CyOx-1 and PLA2c, but not CyOx-2, in response to EGF. Treatment with EGF had no effect on either synthesis of the low molecular weight, group II PLA2, accumulation of its transcript, or the transcription rate of its gene. Coordinate regulation of activities of PLA2 and CyOx in response to EGF did not parallel the mitogenic effects of EGF on confluent MEPM cells
Gender differences and the timing of first marriages
In this article we provide a simple model of the marriage market where singles search for spouses. In our model economy men and women live for many years and they differ in their survival probabilities, in their fecundity, and in their earnings. We show that modelling the marriage decision in a very simple model economy is sufficient to account for much of the observed marriage behavior in the United States in the year 2000. We conclude that gender differences in fecundity are all important in accounting for marriage behavior, and that differences in earnings matter little. We also conclude that, even though they are in short supply, the market power of fecund women is not enough for them to demand compensation in all cases. And that studying the marriage decision without modelling explicitly the roles played by age and by fecundity, as has been typically done by the previous literature, makes little sense.Marriage, Search, Sex ratio
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