High Sensing Properties of 3 wt % Pd-Doped SmFe_1–<i>x</i>Mg_<i>x</i>O₃ Nanocrystalline Powders to Acetone Vapor with Ultralow Concentrations under Light Illumination

Nanocrystalline powders of 3 wt % Pd-doped SmFe_1–<i>x</i>Mg_<i>x</i>O₃ (<i>x</i> = 0, 0.1, 0.2, and 0.3) were prepared by a sol–gel method and annealed at 750 °C. Pd:SmFe_0.9Mg_0.1O₃ has a maximum response at 220 °C. When exposed to 0.5 ppm acetone vapor, the response of undoped SmFeO₃ is 2.26 and the response of Pd:SmFe_0.9Mg_0.1O₃ is 7.16. Under light illumination, Pd:SmFe_0.9Mg_0.1O₃ has a better sensing performance and lower optimal operating temperature. The sensor shows good selectivity and stability for acetone vapor. The high response and good selectivity of Pd:SmFe_0.9Mg_0.1O₃ to ultralow concentrations of acetone vapor indicate its potential for applications in many areas

Electrical Control of Spin Hall Effect in Pt by Hydrogen Ion Adsorption and Desorption

The manipulation of charge-to-spin current conversion and spin–orbit torque (SOT) is of great interest due to its profound physics and potential applications. Controlling the spin current through the electric field provides a perspective for highly efficient SOT devices. Here, we use H2O-doped ionic liquid gating to realize the reversible and nonvolatile manipulation of the spin Hall effect of Pt, and the spin Hall angle can be modulated by 48% within an accessible gate voltage range. The increase in the spin Hall angle is demonstrated to be caused by the adsorption of hydrogen ions on the Pt surface and the consequent enhancement of the spin Hall conductivity under positive voltage. Furthermore, the enhancement of the spin Hall angle is beneficial to reduce the critical current density for driving the domain wall motion. These results supply a method for the dynamic control of the charge-to-spin current conversion, which will promote the development of spintronic devices driven by electric fields

Characteristics of studies included in the meta-analysis.

<p>SI (staining index score): staining intensity x proportion of positively stained cells. OS: overall survival. DFS: disease free survival. MFS: metastasis free survival. LRFS: local recurrence free survival. DMFS: distant metastasis free survival.</p><p>EI: expression index, it was calculated from the formula 1,000 9 2(-DCt), where DCt = Ct (HOTAIR) - Ct (GAPDH). NA: not available.</p><p>*1 denoted as obtaining HRs directly from publications; 2 denoted as calculating HRs from the total number of events and its <i>p</i>-value; 3 denoted as extracting HRs from Kaplan-Meier curves.</p><p>Characteristics of studies included in the meta-analysis.</p

Cell cycle distribution and apoptotic activity of combined H101-Notch1-siRNA on UM cells.

<p>(A) and (B) Cell cycle distribution of OCM1 and VUP cells following treatment with siNotch1 and/or H101. OCM1 and VUP cells were harvested 72 hours after co-treatment with siNotch1 (50nmol/L) and H101 (MOI = 100), and propidium iodide staining and FACS analysis were used to analyze the cell cycle distribution. S-phase arrest was detected in the H101 and H101-Notch1-siRNA groups. (C) and (D) Apoptotic activity of OCM1 and VUP cells. Cells were measured by flow cytometry analysis 72 hours after co-treatment with siNotch1 (50nmol/L) and/or H101 (MOI = 100). Upper left: cells affected by necrosis only; upper right: cells affected with both apoptosis and necrosis; lower left: normal cells; lower right: cells affected by apoptosis only. Data are expressed as mean ± SD. of three independent experiments. (*: p<0.05, **: p<0.01, compared with untreated tumor cells). (E) and (F) Relative ratio percentage of apoptosis (cells in lower right group) and necrosis (cells in upper left group) in OCM1 and VUP cells. The percentages of apoptosis and necrosis cells were analyzed according to (C) and (D).</p

Meta analysis of the pooled HRs of OS of different types of cancer with increased <i>HOTAIR</i> expression.

<p>(A) Subgroup analysis of HRs of OS by factor of region. (B) Subgroup analysis of HRs of OS by factor of score. (C) Subgroup analysis of HRs of OS by factor of sample size. (D) Subgroup analysis of HRs of OS by factor of type of cancer.</p

Antitumor effect of combined H101-Notch1-siRNA treatment in an OCM1 tumor xenograft mouse model.

<p>(A) Tumor volume following treatments. Subcutaneous tumors were established by implanting OCM1 cells in nude mice (n = 10). (B) Tumor weight on day 24 after first injection (n = 5). (C) Representative pictures of tumor specimens of each treatment group 24 days after first injection. (D) Percentage of mouse survival over 120 days (n = 5). Percent survival was analyzed by Kaplan-Meier survival analysis. Data represent mean ± SD. (**: p<0.01, ***: p<0.001, compared with control group).</p

Notch1 gene knockdown by siRNA.

<p>(A) RT-PCR results of Notch1 in UM cells. OCM1 and VUP cells were analyzed using specific primers for Notch1 mRNA. A 100 bp DNA ladder molecular marker served as the reference. PCR bands were normalized using the internal control β-actin. (B) Western blot analysis of Notch1 protein in UM cells. All experiments were performed 72 hours following siNotch1(50nmol/L) and control siRNA(50nmol/L) transfection with or without H101 infection (MOI = 100). (C) Western bandScan was used to analyze the gray scale values for different electrophoretic bands, and the relative ratio of the gray scale values between the target Notch1 band and the β-actin internal reference was determined. Notch1 protein: 120 kDa, β-actin protein: 42 kDa.</p

Results of subgroup analysis of pooled hazard ratios of overall survival of different types of cancer with increased <i>HOTAIR</i> expression.

<p>Results of subgroup analysis of pooled hazard ratios of overall survival of different types of cancer with increased <i>HOTAIR</i> expression.</p

Meta analysis of the independent role of <i>HOTAIR</i> in OS/recurrence/metastasis of different types of cancer.

<p>Meta analysis of the independent role of <i>HOTAIR</i> in OS/recurrence/metastasis of different types of cancer.</p

Results of subgroup analysis of pooled hazard ratios of recurrence-free survival and metastasis-free survival of cancer with increased <i>HOTAIR</i> expression.

<p>Results of subgroup analysis of pooled hazard ratios of recurrence-free survival and metastasis-free survival of cancer with increased <i>HOTAIR</i> expression.</p