Tibetan Dust Accumulation Linked to Ecological and Landscape Response to Global Climate Change

The Tibetan Plateau (TP) is a hotspot of earth system research, and understanding its landscape and ecosystem evolution has been hampered by the lack of time-constrained geological records. Geochronological data from 14 loess sites covering a large region in the Tibetan interior show that the TP loess, rather than accumulating during glacial periods, began aggrading at either 13.4 ± 0.4 or 9.9 ± 0.2 ka. An ecological threshold was crossed, when warmer and wetter conditions resulted in increased vegetation cover enabling dust trapping. This dust accumulation model is out of phase with that of the Chinese Loess Plateau (CLP) where high sedimentation rates occurred during the cold/dry glacial stages. The TP loess accumulation is in response to global climate change, at both orbital (glacial/interglacial) and millennial (e.g., Younger Dryas event) time scales, despite more complexity via ecological and landscape processes than the CLP loess. It is very important to understand the processes of landscape and ecosystem evolution in Tibet to adapt to and mitigate the consequences from potential abrupt future climate changes, but not enough well-dated geological records are available. In this study, we present stratigraphic and numerical age results from 14 loess sites covering a large region in the Tibetan interior. Results show that Tibetan loess began aggrading at either 13.4 ± 0.4 or 9.9 ± 0.2 thousand years ago. Tibetan loess accumulated during warm/interglacial conditions of the Holocene and not during the last glacial period when loess aggradation rates in the Chinese Loess Plateau were high. In Tibet, vegetation cover, which was lowered during the last glacial period, increased during Holocene warming allowing for loess accumulation

FRET-Based Semiconducting Polymer Dots for pH Sensing

Förster resonance energy transfer (FRET)-based polymer dots (Pdots), fabricated by semiconducting polymers and exhibiting excellent properties, have attracted much interest in the last decade, however, full polymer-dot-based pH sensors are seldom systematically exploited by researchers. In this work, we constructed a kind of blend polymer dot, utilizing poly[(9,9-dihexyl-9H-fluorene-2,7-vinylene)-co-(1-methoxy-4-(2-ethylhexyloxy)-2,5-phenylenevinylene)] (PFV) as the donor, poly[2,5-bis(3′,7′-dimethyloctyloxy)-1,4-phenylenevinylene] (BDMO-PPV) as the acceptor, and polysytrene graft EO functionalized with carboxy (PS-PEG-COOH) to generate surface carboxyl groups. This type of Pdot, based on the FRET process, was quite sensitive to pH value changes, especially low pH environments. When the pH value decreases down to 2 or 1, the fluorescence spectrum of Pdots-20% exhibit spectral and intensity changes at the same time, and fluorescence lifetime changes as well, which enables pH sensing applications. The sharpening of the emission peak at ~524 nm, along with the weakening and blue shifts of the emission band at ~573 nm, imply that the efficiency of the energy transfer between PFV and BDMO-PPV inside the Pdots-20% decreased due to polymer chain conformational changes. The time-resolved fluorescence measurements supported this suggestion. Pdots constructed by this strategy have great potential in many applications, such as industrial wastewater detection, in vitro and intracellular pH measurement, and DNA amplification and detection

DNA-Assisted Assembly of Gold Nanostructures and Their Induced Optical Properties

Gold nanocrystals have attracted considerable attention due to their excellent physical and chemical properties and their extensive applications in plasmonics, spectroscopy, biological detection, and nanoelectronics. Gold nanoparticles are able to be readily modified and arranged with DNA materials and protein molecules, as well as viruses. Particularly DNA materials with the advantages endowed by programmability, stability, specificity, and the capability to adapt to functionalization, have become the most promising candidates that are widely utilized for building plenty of discrete gold nanoarchitectures. This review highlights recent advances on the DNA-based assembly of gold nanostructures and especially emphasizes their resulted superior optical properties and principles, including plasmonic extinction, plasmonic chirality, surface enhanced fluorescence (SEF), and surface-enhanced Raman scattering (SERS)

What makes Allium species effective against pathogenic microbes?

The antimicrobial activity of garlic (Allium sativum L.) has been known since ancient times. The first citation dates back to the Egyptian period of 15th century B.C. when garlic was reported to be used in folk medicine as a remedy for microbial infections. Scientific investigations on garlic started in 1858 with the work of Pasteur who first noted antibacterial properties of garlic extracts. From that date to the discovery of antibiotics, garlic has been used against amoebic dysentery and epidemic diseases such as typhus, cholera, diphtheria, and tuberculosis. But what makes garlic and Allium species effective against pathogenic microbes? The volatile sulphur compound allicin and other thiosulfinates, giving pungency to Allium plants, are well-studied and are the main element responsible for garlic activity against microbes. The thiosulfinates or alkane(ene) thial-S-oxide are formed by the action of the enzyme alliinase (EC 4.4.1.4) from their respective S-alk(en)yl cysteine sulfoxides when the bulbs are cut. However, depending on the Allium species, and under differing conditions, thiosulfinates can decompose to form additional sulfur constituents, including diallyl, methyl allyl, and dipropyl mono-, di-, tri- e tetra-sulfides, and (E)- and (Z)-ajoene without losing antimicrobial activity. Besides these apolar compounds, onion and garlic are characterized by more polar compounds of steroidal and phenolic origin, often glycosilated, showing also interesting antimicrobial activity. These latter compounds, compared to the more studied thiosulfinates, have the advantages of not being pungent an are more stable during cooking. Recently, there has been increasing scientific attention given to such compounds. Compounds possessing nitrogen atoms, like alkaloids and polypeptides, have also been isolated from these plants and have shown antimicrobial activity. In this paper, the literature about the major volatile and non-volatile organic compounds of garlic and other Allium plants has been reviewed. Particular attention is given to the compounds possessing antimicrobial activity and to the correlation between the observed activity and the chemical structure of the tested compound