A Survey on Datasets for Decision-making of Autonomous Vehicle

Autonomous vehicles (AV) are expected to reshape future transportation systems, and decision-making is one of the critical modules toward high-level automated driving. To overcome those complicated scenarios that rule-based methods could not cope with well, data-driven decision-making approaches have aroused more and more focus. The datasets to be used in developing data-driven methods dramatically influences the performance of decision-making, hence it is necessary to have a comprehensive insight into the existing datasets. From the aspects of collection sources, driving data can be divided into vehicle, environment, and driver related data. This study compares the state-of-the-art datasets of these three categories and summarizes their features including sensors used, annotation, and driving scenarios. Based on the characteristics of the datasets, this survey also concludes the potential applications of datasets on various aspects of AV decision-making, assisting researchers to find appropriate ones to support their own research. The future trends of AV dataset development are summarized

Cryogenic temperatures as a path towards high-Q terahertz metamaterials

Optical properties of planar thin film metamaterials were measured at room and liquid nitrogen temperatures using terahertz time-domain spectroscopy. The operation of metamaterials at cryogenic temperatures is anticipated to be a promising path towards low-loss metamaterials since nonradiative losses are strongly suppressed due to higher charge mobility. A 14% increase in the quality factor of the resonances was experimentally observed. It was limited by the high electron scattering rate due to defects in thin films. Supplementary simulations assuming metamaterials made of thick films reveal a temperature controlled behaviour and a 40% increase of the Q-factor at 10 K.Comment: 6 pages, 4 figure

Kynurenine aminotransferase 3/glutamine transaminase L/cysteine conjugate beta-lyase 2 is a major glutamine transaminase in the mouse kidney

AbstractBackgroundKynurenine aminotransferase 3 (KAT3) catalyzes the transamination of Kynurenine to kynurenic acid, and is identical to cysteine conjugate beta-lyase 2 (CCBL2) and glutamine transaminase L (GTL). GTL was previously purified from the rat liver and considered as a liver type glutamine transaminase. However, because of the substrate overlap and high sequence similarity of KAT3 and KAT1, it was difficult to assay the specific activity of each KAT and to study the enzyme localization in animals.MethodsKAT3 transcript and protein levels as well as enzyme activity in the liver and kidney were analyzed by regular reverse transcription-polymerase chain reaction (RT-PCR), real time RT-PCR, biochemical activity assays combined with a specific inhibition assay, and western blotting using a purified and a highly specific antibody, respectively.ResultsThis study concerns the comparative biochemical characterization and localization of KAT 3 in the mouse. The results showed that KAT3 was present in both liver and kidney of the mouse, but was much more abundant in the kidney than in the liver. The mouse KAT3 is more efficient in transamination of glutamine with indo-3-pyruvate or oxaloacetate as amino group acceptor than the mouse KAT1.ConclusionsMouse KAT3 is a major glutamine transaminase in the kidney although it was named a liver type transaminase.General significanceOur data highlights KAT3 as a key enzyme for studying the nephrotoxic mechanism of some xenobiotics and the formation of chemopreventive compounds in the mouse kidney. This suggests tissue localizations of KAT3/GTL/CCBL2 in other animals may be carefully checked

Development of an activatable far-red fluorescent probe for rapid visualization of hypochlorous acid in live cells and mice with neuroinflammation

Recent investigations have suggested that abnormally elevated levels of HOCl may be tightly related to the severity of neuroinflammation. Although some successes have been achieved, fluorescent probes with far-red fluorescence emission and capable of detecting HOCl with high specificity in pure aqueous solution are still urgently needed. Herein, a responsive far-red fluorescent probe, DCI-H, has been constructed to monitor HOCl activity in vivo and in vitro. DCI-H could rapidly respond to HOCl within 120 s and had a low detection limit for HOCl of 1.5 nM. Importantly, physiologically common interfering species, except for HOCl, did not cause a change in the fluorescence intensity of DCI-HOCl at 655 nm. The results of confocal imaging demonstrated the ability of DCI-H to visualize endogenous HOCl produced by MPO-catalyzed H2O2/Cl− and LPS stimulation. With the assistance of DCI-H, upregulation of HOCl levels was observed in the mice model of LPS-induced neuroinflammation. Thus, we believed that DCI-H provided a valuable tool for HOCl detection and diagnosis of inflammation-related diseases