Mobile Internet based M-Commerce Management Architecture & System

The mobile Internet exits already in very many forms on the market. However, there are definitely still a lot of possibilities to improve the current concepts and solution, and thus a lot of room for future R&D activities. This paper is divided five parts as followings: First of all, introduction; Secondly, the basic concept of mobile Internet is introduced, and its’ develop- ment status is described simply; Thirdly, the process of come into being M-commerce based on Internet and the existing modes of M-commerce are discussed respectively; the differences between E-commerce and Mcommerce are also shown in the paper; Fourthly, an M-commerce system model is presented, the model involves its’ basic elements such as hierarchical architecture, management mechanism, system decision-making, application procedure etc; Fifthly, development trend and application fields for coming the new economics times are forecasted; Finally, how to build a M-commerce management system and make applications for business via CERNET** (one of the biggest Internet platform in China) are introduced primarily in end of the paper

Antibiotic drugs targeting bacterial RNAs

AbstractRNAs have diverse structures that include bulges and internal loops able to form tertiary contacts or serve as ligand binding sites. The recent increase in structural and functional information related to RNAs has put them in the limelight as a drug target for small molecule therapy. In addition, the recognition of the marked difference between prokaryotic and eukaryotic rRNA has led to the development of antibiotics that specifically target bacterial rRNA, reduce protein translation and thereby inhibit bacterial growth. To facilitate the development of new antibiotics targeting RNA, we here review the literature concerning such antibiotics, mRNA, riboswitch and tRNA and the key methodologies used for their screening