729 research outputs found

    Reaching the Oldest Population: Improving the Coverage of Service for People over 85 Years Old in Broome County

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    From 2000 to 2010, the population of those over 85 years old ( the oldest old) in Broome County has increased by 23.19%. However at the same time, the number of the oldest old who receive service from Broome County Office for Aging (BCOFA) has decreased by 10%. As the only department in Broome County government which provides services specifically targeting senior citizens, BCOFA may differ from the needs of those who do not and what strategies could be used to improve the service coverage for this problem

    Credit risk evaluation by using nearest subspace method

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    AbstractIn this paper, a classification method named nearest subspace method is applied for credit risk evaluation. Virtually credit risk evaluation is a very typical classification problem to identify “good” and “bad” creditors. Currently some machine learning technologies, such as support vector machine (SVM), have been discussed widely in credit risk evaluation. But there are many effective classification methods in pattern recognition and artificial intelligence have not been tested for credit evaluation. This paper presents to use nearest subspace classification method, a successful face recognition method, for credit evaluation. The nearest subspace credit evaluation method use the subspaces spanned by the creditors in same class to extend the training set, and the Euclidean distance from a test creditor to the subspace is taken as the similarity measure for classification, then the test creditor belongs to the class of nearest subspace. Experiments on real world credit dataset show that the nearest subspace credit risk evaluation method is a competitive method

    Moving P2P Live Streaming to Mobile and Ubiquitous Environment

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    Media streams distribution over a wired network to static hosts can be realized by Client/Server mode or Peer-to-Peer overlay networks. However, if the end hosts are mobile over heterogeneous wireless access networks, one needs to consider many operational issues such as network detection, handoff, join and leave latency, and desired level of quality of service, as well as caching. In the latest researches, one popular P2P live streaming system, called AnySee, over the wired network, has been deployed and widely used. Based on the AnySee system, this paper proposed and implemented one hybrid live streaming system, AnySee-Mobile, under wired and wireless environment. In the system, one wireless peer will be selected to act as an agent. One agent has two main functions, to request media from P2P overlay network as a normal peer, and to multicast media to WLAN as a multicast source. In this paper we study, how to elect one multicast agent in WLAN. Several experimentations have been made and proved that the system has good user experiences and performances

    Intercellular protein–protein interactions at synapses

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    Chemical synapses are asymmetric intercellular junctions through which neurons send nerve impulses to communicate with other neurons or excitable cells. The appropriate formation of synapses, both spatially and temporally, is essential for brain function and depends on the intercellular protein-protein interactions of cell adhesion molecules (CAMs) at synaptic clefts. The CAM proteins link pre- and post-synaptic sites, and play essential roles in promoting synapse formation and maturation, maintaining synapse number and type, accumulating neurotransmitter receptors and ion channels, controlling neuronal differentiation, and even regulating synaptic plasticity directly. Alteration of the interactions of CAMs leads to structural and functional impairments, which results in many neurological disorders, such as autism, Alzheimer's disease and schizophrenia. Therefore, it is crucial to understand the functions of CAMs during development and in the mature neural system, as well as in the pathogenesis of some neurological disorders. Here, we review the function of the major classes of CAMs, and how dysfunction of CAMs relates to several neurological disorders.Cell BiologySCI(E)中国科学引文数据库(CSCD)[email protected]; [email protected]

    Abyss Aerosols

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    Bubble bursting on water surfaces is believed to be a main mechanism to produce submicron drops, including sea spray aerosols, which play a critical role in forming cloud and transferring various biological and chemical substances from water to the air. Over the past century, drops production mechanisms from bubble bursting have been extensively studied. They usually involve the centrifugal fragmentation of liquid ligaments from the bubble cap during film rupture, the flapping of the cap film, and the disintegration of Worthington jets after cavity collapse. Here, we show that a dominant fraction of previously identified as 'bubble bursting' submicron drops are in fact generated via a new mechanism underwater, inside the bubbles themselves before they have reached the surface. These drops are then carried within the rising bubbles towards the water surface and are released in air at bubble bursting. Evidence suggests that these drops originate from the flapping instability of the film squeezed between underwater colliding bubbles. This finding fundamentally reshapes our understanding of sea spray aerosol production and establishes a new role for underwater bubble collisions regarding the nature of transfers through water-air interfaces.Comment: 50 pages, 4 figures, and 10 extended data figure

    Analysis of global burden of bacterial infections: an interpretation of Global mortality associated with 33 bacterial pathogens in 2019

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    The Global Burden of Bacterial Infections report showed that in 2019, there were approximately 13.7 million deaths worldwide due to infection (95% UI ranging from 10.9 million to 17.1 million), and bacterial infection related deaths accounted for 13.6% (10.1%-18.1%) of global deaths, making it the second leading cause of death globally, second only to ischemic heart disease. Eleven infectious syndromes involve 33 bacterial pathogens and are associated with 7.7 million deaths worldwide (5.7 million to 10.2 million). Lower respiratory tract infections have caused approximately 4 million deaths worldwide (3.33 million to 4.89 million), with Streptococcus pneumoniae causing the most deaths at 653 000 (553 000 to 777 000); Blood flow infections have caused 2.91 million people (1.74 million to 4.53 million), with Staphylococcus aureus causing the most deaths, at 299 000 people (166 000 to 485 000); Peritoneal and intra-abdominal infections have caused 1.28 million deaths (826 000 to 1.86 million), with Escherichia coli causing the most deaths, reaching 290000 (188 000 to 423 000). The Global Burden of Bacterial Infections report also shows that in 2019, Staphylococcus aureus was associated with over 1 million deaths (resulting in 1.105 million deaths); Escherichia coli causes 450 000 (329 000 to 602 000) female and 500 000 (355 000 to 684 000) male deaths worldwide, while Streptococcus pneumoniae causes over 750 000 deaths worldwide; Klebsiella pneumoniae causes over 750 000 deaths worldwide; Pseudomonas aeruginosa has caused over 500 000 deaths worldwide. The Global Burden of Bacterial Infections report data shows that the pathogens most associated with mortality worldwide vary by age. Staphylococcus aureus is the deadliest pathogen among people aged 15 and above, with 940 000 deaths (682 000 to 1 276 000) in this age group; Salmonella typhi is most associated with mortality in children aged 5-14, with a death toll of 49 000 (23 000-86 000); Streptococcus pneumoniae is most associated with the death of newborns to 4-year-old children, with a death toll of 225 000 (180 000 to 281 000). The Global Burden of Bacterial Infections report estimates the mortality rates of various pathogens and infectious syndromes, some of which were previously unknown and some were severely underestimated, especially in low-and middle-income countries where the burden is disproportionately high. However, there is a lack of corresponding data and research in China, and it is necessary to conduct corresponding surveys and research to develop innovative strategies

    Infrared carpet cloak designed with uniform silicon grating structure

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    Through a particularly chosen coordinate transformation, we propose an optical carpet cloak that only requires homogeneous anisotropic dielectric material. The proposed cloak could be easily imitated and realized by alternative layers of isotropic dielectrics. To demonstrate the cloaking performance, we have designed a two-dimensional version that a uniform silicon grating structure fabricated on a silicon-on-insulator wafer could work as an infrared carpet cloak. The cloak has been validated through full wave electromagnetic simulations, and the non-resonance feature also enables a broadband cloaking for wavelengths ranging from 1372 to 2000 nm.Comment: 11 pages, 4 figure
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