The design and realization of flexible wearable wireless music controller

By using flexible sensors and micro-control units, a wireless controller that can be integrated into clothing for cross-platform music control has been designed and implemented, providing a new idea for making a simple and low-cost flexible wearable sensing system. The design and implementation of a wireless controller that can be integrated into clothing for cross-platform music control provides a new idea for the preparation of a simple and low-cost flexible wearable sensing system. Based on the flexible fabric sensing material, a simple structured sensor piece is proposed as a button for the controller with good wearing comfort. The sensor element is capable of sensing finger presses up to 15kPa. ESP32 is used as a micro-control unit for sensing signal acquisition and data processing. Using the Bluetooth chip integrated inside the ESP32, the controller can be connected with terminal devices of different platforms for wireless data transmission. The results show that the prepared wireless music controller can be stably connected with both Windows computer terminal and Android cell phone terminal, and the sensor recognition accuracy of finger press is 99.7%, which indicates that the flexible fabric sensor has a broad application prospect in the field of wearable devices

Amyloidogenesis Abolished by Proline Substitutions but Enhanced by Lipid Binding

The influence of lipid molecules on the aggregation of a highly amyloidogenic segment of human islet amyloid polypeptide, hIAPP20–29, and the corresponding sequence from rat has been studied by all-atom replica exchange molecular dynamics (REMD) simulations with explicit solvent model. hIAPP20–29 fragments aggregate into partially ordered β-sheet oligomers and then undergo large conformational reorganization and convert into parallel/antiparallel β-sheet oligomers in mixed in-register and out-of-register patterns. The hydrophobic interaction between lipid tails and residues at positions 23–25 is found to stabilize the ordered β-sheet structure, indicating a catalysis role of lipid molecules in hIAPP20–29 self-assembly. The rat IAPP variants with three proline residues maintain unstructured micelle-like oligomers, which is consistent with non-amyloidogenic behavior observed in experimental studies. Our study provides the atomic resolution descriptions of the catalytic function of lipid molecules on the aggregation of IAPP peptides

OpenDataVal: a Unified Benchmark for Data Valuation

Assessing the quality and impact of individual data points is critical for improving model performance and mitigating undesirable biases within the training dataset. Several data valuation algorithms have been proposed to quantify data quality, however, there lacks a systemic and standardized benchmarking system for data valuation. In this paper, we introduce OpenDataVal, an easy-to-use and unified benchmark framework that empowers researchers and practitioners to apply and compare various data valuation algorithms. OpenDataVal provides an integrated environment that includes (i) a diverse collection of image, natural language, and tabular datasets, (ii) implementations of eleven different state-of-the-art data valuation algorithms, and (iii) a prediction model API that can import any models in scikit-learn. Furthermore, we propose four downstream machine learning tasks for evaluating the quality of data values. We perform benchmarking analysis using OpenDataVal, quantifying and comparing the efficacy of state-of-the-art data valuation approaches. We find that no single algorithm performs uniformly best across all tasks, and an appropriate algorithm should be employed for a user's downstream task. OpenDataVal is publicly available at https://opendataval.github.io with comprehensive documentation. Furthermore, we provide a leaderboard where researchers can evaluate the effectiveness of their own data valuation algorithms.Comment: 25 pages, NeurIPS 2023 Track on Datasets and Benchmark