Anomalous gauge couplings of the Higgs boson at the CERN LHC: Semileptonic mode in WW scatterings

We make a full tree level study of the signatures of anomalous gauge couplings of the Higgs boson at the CERN LHC via the semileptonic decay mode in WW scatterings. Both signals and backgrounds are studied at the hadron level for the Higgs mass in the range 115 GeV to 200 GeV. We carefully impose suitable kinematical cuts for suppressing the backgrounds. To the same sensitivity as in the pure leptonic mode, our result shows that the semileptonic mode can reduce the required integrated luminosity by a factor of 3. If the anomalous couplings in nature are actually larger than the sensitivity bounds shown in the text, the experiment can start the test for an integrated luminosity of 50 inverse fb.Comment: PACS numbers updated. Version published in Phys.Rev.D79,055010(2009

A description of the transverse momentum distributions of charged particles produced in heavy ion collisions at RHIC and LHC energies

By assuming the existing of memory effects and long-range interactions in the hot and dense matter produced in high energy heavy ion collisions, the nonextensive statistics together with the relativistic hydrodynamics including phase transition is used to discuss the transverse momentum distributions of charged particles produced in heavy ion collisions. It is shown that the combined contributions from nonextensive statistics and hydrodynamics can give a good description to the experimental data in Au+Au collisions at sqrt(s_NN )= 200 GeV and in Pb+Pb collisions at sqrt(s_NN) )= 2.76 TeV for pi^(+ -) , K^(+ -) in the whole measured transverse momentum region, and for p(p-bar) in the region of p_T<= 2.0 GeV/c. This is different from our previous work, where, by using the conventional statistics plus hydrodynamics, the describable region is only limited in p_T<= 1.1 GeV/c.Comment: 14 pages, 3 figures, 2 table

(Z)-2-Hydr­oxy-3-(4-methoxy­phen­yl)acrylic acid

In the structure of the title compound, C10H10O4, inversion dimers linked by pairs of O—H⋯O hydrogen bonds link the carboxylic acid groups. Further O—H⋯O links cross-link the dimers into sheets running along the b-axis direction

(Z)-2-Acetamido-3-(4-chloro­phen­yl)acrylic acid

In the title compound, C11H10ClNO3, the mol­ecule consists of a benzene ring and an acetamido­acrylic acid unit on opposite sides of the C=C double bond. In the crystal, inter­molecular O—H⋯O and N—H⋯O hydrogen bonds assemble the mol­ecules into infinite two-dimensional ribbons. These ribbons are linked into a network by inter­molecular C—H⋯π contacts

Nonlinear Floquet dynamics of spinor condensates in an optical cavity: Cavity-amplified parametric resonance

We investigate Floquet dynamics of a cavity-spinor Bose-Einstein condensate coupling system via periodic modulation of the cavity pump laser. Parametric resonances are predicted and we show that due to cavity feedback-induced nonlinearity the spin oscillation can be amplified to all orders of resonance, thus facilitating its detection. Real-time observation on Floquet dynamics via cavity output is also discussed

Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10

Aim: Human CXCR3, a seven-transmembrane segment (7TMS), is predominantly expressed in Th1-mediated responses. Interferon-γ-inducible protein 10 (IP-10) is an important ligand for CXCR3. Their interaction is pivotal for leukocyte migration and activation. Tyrosine sulfation in 7TMS is a posttranslational modification that contributes substantially to ligand binding. We aimed to study the role of tyrosine sulfation of CXCR3 in the protein's binding to IP-10. Methods: Plasmids encoding CXCR3 and its mutants were prepared by PCR and site-directed mutagenesis. HEK 293T cells were transfected with plasmids encoding CXCR3 or its variants using calcium phosphate. Transfected cells were labeled with [35S]-cysteine and methionine or [35S]-Na2SO3 and then analyzed by immunoprecipitation to measure sulfation. Experiments with 125I-labeled IP-10 were carried out to evaluate the affinity of CXCR3 for its ligand. Calcium influx assays were used to measure intercellular signal transduction. Results: Our data show that sulfate moieties are added to tyrosines 27 and 29 of CXCR3. Mutation of these two tyrosines to phenylalanines substantially decreases binding of CXCR3 to IP-10 and appears to eliminate the associated signal transduction. Tyrosine sulfation of CXCR3 is enhanced by tyrosyl protein sulfotransferases (TPSTs), and it is weakened by shRNA constructs. The binding ability of CXCR3 to IP-10 is increased by TPSTs and decreased by shRNAs. Conclusions: This study identifies two sulfated tyrosines in the N-terminus of CXCR3 as part of the binding site for IP-10, and it underscores the fact that tyrosine sulfation in the N-termini of 7TMS receptors is functionally important for ligand interactions. Our study suggests a molecular target for inhibiting this ligand-receptor interaction