3-(3,5-Dimethyl-1H-pyrazol-1-yl)propanamide

In the crystal of the title compound, C8H13N3O, mol­ecules are linked by inter­molecular N—H⋯N and N—H⋯O hydrogen bonds into a three-dimensional network. Additional stabilization is provided by weak inter­molecular C—H⋯O hydrogen bonds

Macrophage migration inhibitory factor (MIF) family in arthropods : Cloning and expression analysis of two MIF and one D-dopachrome tautomerase (DDT) homologues in Mud crabs, Scylla paramamosain

Acknowledgements This research was supported by grants from the National Natural Science Foundation of China (Nos. 31172438 and U1205123), the Natural Science Foundation of Fujian Province (No. 2012J06008 and 201311180002) and the projects-sponsored by SRF. TW received funding from the MASTS pooling initiative (The Marine Alliance for Science and Technology for Scotland) funded by the Scottish Funding Council (grant reference HR09011) and contributing institutions.Peer reviewedPostprin

(E)-(2,4-Dichloro­phen­yl)[2-hydr­oxy-6-(methoxy­imino)cyclo­hex-1-en­yl]methanone

The title compound, C14H13Cl2NO3, was obtained as the product of an attempted synthesis of herbicidally active compounds containing oxime ether and cyclo­hexenone groups. In the crystal structure, the mol­ecule adopts an endocyclic enol tautomeric form and the cyclo­hexene ring adopts a distorted envelope form. The oxime ether group has an E configuration, with the meth­oxy group anti to the ortho-chloro substitutent. Intra­molecular O—H⋯O and inter­molecular C—H⋯O hydrogen bonds are found in the crystal structure

Identify submitochondria and subchloroplast locations with pseudo amino acid composition: Approach from the strategy of discrete wavelet transform feature extraction

AbstractIt is very challenging and complicated to predict protein locations at the sub-subcellular level. The key to enhancing the prediction quality for protein sub-subcellular locations is to grasp the core features of a protein that can discriminate among proteins with different subcompartment locations. In this study, a different formulation of pseudoamino acid composition by the approach of discrete wavelet transform feature extraction was developed to predict submitochondria and subchloroplast locations. As a result of jackknife cross-validation, with our method, it can efficiently distinguish mitochondrial proteins from chloroplast proteins with total accuracy of 98.8% and obtained a promising total accuracy of 93.38% for predicting submitochondria locations. Especially the predictive accuracy for mitochondrial outer membrane and chloroplast thylakoid lumen were 82.93% and 82.22%, respectively, showing an improvement of 4.88% and 27.22% when other existing methods were compared. The results indicated that the proposed method might be employed as a useful assistant technique for identifying sub-subcellular locations. We have implemented our algorithm as an online service called SubIdent (http://bioinfo.ncu.edu.cn/services.aspx)