999 research outputs found
PCN117 COST-UTILITY MODEL TO EVALUATE ADJUVANT CHEMOTHERAPY FOR EARLY BREAST CANCER IN THE USA
A Composite Trust Model for Secure Routing in Mobile Ad-Hoc Networks
It is imperative to address the issue of secure routing in mobile ad-hoc networks (MANETs) where the nodes seek for cooperative and trusted behaviour from the peer nodes in the absence of well-established infrastructure and centralized authority. Due to the inherent absence of security considerations in the traditional ad-hoc routing protocols, providing security and reliability in the routing of data packets is a major challenge. This work addresses this issue by proposing a composite trust metric based on the concept of social trust and quality-of-service (QoS) trust. Extended from the ad-hoc on-demand distance vector (AODV) routing protocol, we propose an enhanced trust-based model integrated with an attack-pattern discovery mechanism, which attempts to mitigate the adversaries craving to carry out distinct types of packet-forwarding misbehaviours. We present the detailed mode of operations of three distinct adversary models against which the proposed scheme is evaluated. Simulation results under different network conditions depict that the combination of social and QoS trust components provides significant improvement in packet delivery ratio, routing overhead, and energy consumption compared to an existing trust-based scheme
Predictors of oral bisphosphonate prescriptions in post-menopausal women with osteoporosis in a real-world setting in the USA
PDB16 GLYCEMIC CONTROL WITH INSULIN GLARGINE PLUS GLULISINE VERSUS PREMIX IN REALWORLD PRACTICES—A RANDOMIZED, PROSPECTIVE, OBSERVATIONAL STUDY
Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19
© 2020 National Kidney Foundation, Inc. Acute kidney injury (AKI) is common among hospitalized patients with Coronavirus Infectious Disease 2019 (COVID-19), with the occurrence of AKI ranging from 0.5% to 80%. The variability in the occurrence of AKI has been attributed to the difference in geographic locations, race/ethnicity, and severity of illness. AKI among hospitalized patients is associated with increased length of stay and in-hospital deaths. Even patients with AKI who survive to hospital discharge are at risk of developing chronic kidney disease or end-stage kidney disease. An improved knowledge of the pathophysiology of AKI in COVID-19 is crucial to mitigate and manage AKI and to improve the survival of patients who developed AKI during COVID-19. The goal of this article is to provide our current understanding of the etiology and the pathophysiology of AKI in the setting of COVID-19
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