Additional file 1: Figure S1. of miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies

BCL-XL mRNA structure. (A) The 3’-UTR mRNA of BCL-XL contains two predicted miR-377 binding sites. (B) The contextual/local secondary structures around the predicted miRNA target site in the short and full length 3’-UTR of Bcl-xL transcript as predicted by mFold and Nupack RNA folding algorithms. (JPEG 446 kb