2,862 research outputs found
Communication and Posttraumatic Growth: The Power of Positive Declarations
Research has explored the relationship between posttraumatic growth (PTG) and communication trends. Yet, there is a gap in research regarding how positive declarations of desired outcomes can influence PTG and be applied in a therapeutic context. The purpose of this quantitative study was to examine if positive declarations of psychological growth facilitate PTG after trauma and impact levels of hope, anxiety, or depression. A small pilot study was conducted through six counseling sessions with participants (N = 16) divided into either the control (n = 8) or experimental group (n = 8). A novel Positive Communication Approach (PCA), distinguished by linguistic psychoeducation and use of positive declarations, was only implemented with the experimental group. Pretest-posttest data was collected using the SRGS-R, AHS, GAD-7, and PHQ-9 and analyzed by an analysis of covariance (ANCOVA). ANCOVA results indicated no significant difference between group level for each research question. However, cumulative scores on all four questionnaires were higher for the experimental group than the control group, with a more substantial change noted for PTG and hope. The differences between clinical and statistical findings may be attributed to the study’s small sample size. Findings support existing literature regarding communication and PTG while providing an empirical source of support for scripture. Furthermore, PCA may be an effective therapeutic intervention for facilitating PTG by cultivating hope and expectation
Taking care of Tootsie: Making a place for nurses.
Theresa “Tootsie” Smoder, better known as my grandma, always seemed larger than life. She bore eight children in nine years (The “Crazy Eights”), raised them almost single-handedly when her husband died and managed a 160 acre farm. Doing whatever it took to create security and stability for her family, Tootsie worked multiple jobs to feed her brood. She was a social butterfly who always tended to others and modeled the value of caring throughout her life
THE WESTERN HIGH GATE OF MEDINET HABU: PHOTOGRAMMETRIC 3D MODELLING & DOCUMENTATION
[EN] This paper discusses the 3D photogrammetric modelling and documentation of the Western High Gate at Medinet Habu
by the University of Chicago’s Oriental Institute, Epigraphic Survey Project. It provides an overview of technique and
approach, along with a discussion of measurement methods and accuracy.[ES] Este artículo discute el modelado 3D y la documentación fotogramétrica de la alta puerta occidental en Medinet Habu
por el Instituto Oriental del Universidad de Chicago, Proyecto Levantamiento Epigráfico. Proporciona una visión general
de la técnica y el enfoque, junto con una discusión de los métodos de medición y precisión.Murray, O.; Mcdonald, H.; Kimpton, JL. (2016). THE WESTERN HIGH GATE OF MEDINET HABU: PHOTOGRAMMETRIC 3D MODELLING & DOCUMENTATION. En 8th International congress on archaeology, computer graphics, cultural heritage and innovation. Editorial Universitat Politècnica de València. 520-523. https://doi.org/10.4995/arqueologica8.2015.4199OCS52052
Runner Identity and Sponsorship: Evaluating the Rock ‘n’ Roll Marathon
The economic value of participation sport has been reported to eclipse spectator sport significantly. However, scholars have acknowledged the relative lack of research on this important segment of the sport market. The purpose of this study was to analyze the relationship between runner identity and race sponsor effectiveness. Surveys were sent to participants in the Las Vegas Rock ‘n’ Roll Marathon. The survey was constructed to measure runner identity, and sponsor effectiveness as interpreted through rates of recognition, recall and purchase intention. Runners were divided into three groups based on their runner identity score. Of the predictive variables, only runner identity was a significant predictor of sponsor recognition and recall and one of two significant variables for purchase intention. The current study established runner identity as a unique construct and shows how runner identity is tied to measures that can be used by race organizers to attract or retain sponsors
Promising Practices in E-Supervision: Exploring Graduate Speech-Language Pathology Interns’ Perceptions
E-supervision has a potential role in addressing speech-language personnel shortages in rural and difficult to staff school districts. The purposes of this article are twofold: to determine how e-supervision might support graduate speech-language pathologist (SLP) interns placed in rural, remote, and difficult to staff public school districts; and, to investigate interns’ perceptions of in-person supervision compared to e-supervision. The study used a mixed methodology approach and collected data from surveys, supervision documents and records, and interviews. The results showed the use of e-supervision allowed graduate SLP interns to be adequately supervised across a variety of clients and professional activities in a manner that was similar to in-person supervision. Further, e-supervision was perceived as a more convenient and less stressful supervision format when compared to in-person supervision. Other findings are discussed and implications and limitations provided
Swapping in lattice-based cell migration models
Cell migration is frequently modeled using on-lattice agent-based models (ABMs) that employ the excluded volume interaction. However, cells are also capable of exhibiting more complex cell-cell interactions, such as adhesion, repulsion, pulling, pushing, and swapping. Although the first four of these have already been incorporated into mathematical models for cell migration, swapping has not been well studied in this context. In this paper, we develop an ABM for cell movement in which an active agent can "swap" its position with another agent in its neighborhood with a given swapping probability. We consider a two-species system for which we derive the corresponding macroscopic model and compare it with the average behavior of the ABM. We see good agreement between the ABM and the macroscopic density. We also analyze the movement of agents at an individual level in the single-species as well as two-species scenarios to quantify the effects of swapping on an agent's motility
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Bullous dermatoses secondary to anti-PD-L1 agents: a case report and review of the literature
Immune checkpoint inhibitors are used to treat numerous malignancies but may be associated with severe adverse events. Bullous dermatoses, chiefly bullous pemphigoid (BP), are potentially progressive adverse events that cause blistering skin lesions and may involve a significant body surface area. Herein, we report an 87-year-old man with urothelial cell carcinoma undergoing atezolizumab treatment who presented with an acute-onset blistering eruption. Biopsy revealed a subepidermal bulla, direct immunofluorescence revealed linear IgG and C3 deposits at the dermal-epidermal junction, and serum studies revealed elevated levels of antibodies to BP180 and BP230. Anti-PD-L1-induced BP was diagnosed, immunotherapy was withheld, and he was treated with oral doxycycline with niacinamide and clobetasol ointment. He restarted atezolizumab and has successfully received four cycles (every 3 weeks) while continuing this BP treatment regimen. A literature review revealed eight other cases of anti-PD-L1-induced bullous disorders. The incidence of bullous dermatoses with anti-PD-1/anti-PD-L1 agents combined is 1%, whereas the reported incidence for anti-PD-L1 agents alone ranges from 1.3-5%, raising concerns for a higher overall risk. In addition to our case, only one other case reported successful resumption of immunotherapy. Early control and management of immunotherapy-induced BP may reduce complications and prevent treatment discontinuation
Direct genetic demonstration of Gα13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement
G2A is an orphan G protein-coupled receptor (GPCR), expressed predominantly in T and B cells and homologous to a small group of GPCRs of unknown function expressed in lymphoid tissues. G2A is transcriptionally induced in response to diverse stimuli, and its ectopic expression suppresses transformation of B lymphoid precursors by BCR-ABL. G2A induces morphological transformation of NIH 3T3 fibroblasts. Microinjection of constructs encoding G2A into Swiss 3T3 fibroblasts induces actin reorganization into stress fibers that depends on RhoA, but not CDC42 or RAC. G2A elicits RhoA-dependent transcriptional activation of serum response factor. Direct evaluation of RhoA activity demonstrates elevated levels of RhoA-GTP in G2A-expressing cells. Microinjection of embryonic fibroblasts derived from various Galpha knockout mice establishes a requirement for Galpha 13 but not Galpha 12 or Galpha q/11 in G2A-induced actin rearrangement. In conclusion, G2A represents a family of GPCRs expressed in lymphocytes that may link diverse stimuli to cytoskeletal reorganization and transcriptional activation through a pathway involving Galpha 13 and RhoA
Swapping in lattice-based cell migration models
Cell migration is frequently modelled using on-lattice agent-based models (ABMs) that employ the excluded volume interaction. However, cells are also capable of exhibiting more complex cell-cell interactions, such as adhesion, repulsion, pulling, pushing and swapping. Although the first four of these have already been incorporated into mathematical models for cell migration, swapping has not been well studied in this context. In this paper, we develop an ABM for cell movement in which an active agent can `swap' its position with another agent in its neighbourhood with a given swapping probability. We consider a two-species system for which we derive the corresponding macroscopic model and compare it with the average behaviour of the ABM. We see good agreement between the ABM and the macroscopic density. We also analyse the movement of agents at an individual level in the single-species as well as two-species scenarios to quantify the effects of swapping on an agent's motility.<br/
Swapping in lattice-based cell migration models
Cell migration is frequently modelled using on-lattice agent-based models
(ABMs) that employ the excluded volume interaction. However, cells are also
capable of exhibiting more complex cell-cell interactions, such as adhesion,
repulsion, pulling, pushing and swapping. Although the first four of these have
already been incorporated into mathematical models for cell migration, swapping
is an interaction that has not been well studied in this context. In this
paper, we develop an ABM to describe cell movement where an active agent can
`swap' its position with another agent in its neighbourhood with a given
swapping probability. We consider single-species and two-species systems. In
both cases, we derive the corresponding macroscopic model and compare it with
the average behaviour of the ABM. We see good agreement between the ABM and the
macroscopic density. We also derive an expression for the cell-level diffusion
coefficient in terms of the swapping probability and cell density. We conclude
by showing applications of swapping by using the ABM to represent cell movement
with proliferation and cell-cell adhesion.Comment: 32 pages, 12 figures, articl
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