9 research outputs found

    Interactions between currents and the spatial structure of aquatic vegetation

    Get PDF
    Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Civil and Environmental Engineering, 2009.Includes bibliographical references (p. 79-85).Vegetation is present in nearly all aquatic environments, ranging from meandering streams to constructed channels and rivers, as well as in lakes and coastal zones. This vegetation grows in a wide range of flow environments as well, from stagnant water to highly turbulent flows dominated by waves and currents. Feedbacks between the dominant currents and the vegetation not only significantly alter the velocity structure of the flow, but play a large role in determining the spatial structure of the vegetation as well. This thesis examines these interactions through field experiments, review of existing literature and theoretical and analytical models. The first study describes a set of experiments in which vegetation was added to the point bar of a stream meander during base flow. During the next flood event, this vegetation proved to be destabilizing as a portion of the vegetation scoured away and the cross section of the open channel showed clear patterns of erosion. The secondary circulation present in the meander was significantly altered as well. In the second study, the relationship between tidal currents and the spatial distribution of seagrass meadows is examined. Seagrass beds range in their coverage from continuous meadows, to spotty swaths dominated by discrete patches. The relationship between this area coverage and tidal currents, explained by the principles of percolation theory, helps describe why certain distributions of seagrass within a meadow are more stable than others.(cont.) Drawing on the principles and examples established in the first two sections, the final section describes an analytical model for predicting vegetation coverage in a rectangular open channel. The model can allow for fixed banks, such as those in a concrete-lined channel, or can allow erosion of the boundaries, as is possible in natural streams. These two versions of the model show notably different results. Ultimately, this thesis presents multiple cases of the interactions between currents and aquatic vegetation and showcases an important example of a multi-disciplinary research approach in fluid mechanics.by Jeffrey T. Rominger.S.M

    Effects of Added Vegetation on Sand Bar Stability and Stream Hydrodynamics

    Get PDF
    Vegetation was added to a fully developed sandy point bar in the meander of a constructed stream. Significant changes in the flow structure and bed topography were observed. As expected, the addition of vegetative resistance decreased the depth-averaged streamwise velocity over the bar and increased it in the open region. In addition, the secondary circulation increased in strength but became confined to the deepest section of the channel. Over the point bar, the secondary flow was entirely outward, i.e., toward the outer bank. The changes in flow led to changes in bar shape. Although the region of the bar closest to the inner bank accumulated sediment, erosion of the bar and the removal of plants by scouring were observed at the interface between the planted bar and the open channel.National Science Foundation (U.S.) (Grant No. EAR 0738352

    Predicting Hemolytic Uremic Syndrome and Renal Replacement Therapy in Shiga Toxin-producing Escherichia coli-infected Children.

    Get PDF
    BACKGROUND: Shiga toxin-producing Escherichia coli (STEC) infections are leading causes of pediatric acute renal failure. Identifying hemolytic uremic syndrome (HUS) risk factors is needed to guide care. METHODS: We conducted a multicenter, historical cohort study to identify features associated with development of HUS (primary outcome) and need for renal replacement therapy (RRT) (secondary outcome) in STEC-infected children without HUS at initial presentation. Children agedeligible. RESULTS: Of 927 STEC-infected children, 41 (4.4%) had HUS at presentation; of the remaining 886, 126 (14.2%) developed HUS. Predictors (all shown as odds ratio [OR] with 95% confidence interval [CI]) of HUS included younger age (0.77 [.69-.85] per year), leukocyte count ≥13.0 × 103/μL (2.54 [1.42-4.54]), higher hematocrit (1.83 [1.21-2.77] per 5% increase) and serum creatinine (10.82 [1.49-78.69] per 1 mg/dL increase), platelet count \u3c250 \u3e× 103/μL (1.92 [1.02-3.60]), lower serum sodium (1.12 [1.02-1.23 per 1 mmol/L decrease), and intravenous fluid administration initiated ≥4 days following diarrhea onset (2.50 [1.14-5.46]). A longer interval from diarrhea onset to index visit was associated with reduced HUS risk (OR, 0.70 [95% CI, .54-.90]). RRT predictors (all shown as OR [95% CI]) included female sex (2.27 [1.14-4.50]), younger age (0.83 [.74-.92] per year), lower serum sodium (1.15 [1.04-1.27] per mmol/L decrease), higher leukocyte count ≥13.0 × 103/μL (2.35 [1.17-4.72]) and creatinine (7.75 [1.20-50.16] per 1 mg/dL increase) concentrations, and initial intravenous fluid administration ≥4 days following diarrhea onset (2.71 [1.18-6.21]). CONCLUSIONS: The complex nature of STEC infection renders predicting its course a challenge. Risk factors we identified highlight the importance of avoiding dehydration and performing close clinical and laboratory monitoring

    Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

    Get PDF
    Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

    Hydrodynamic and transport phenomena at the interface between flow and aquatic vegetation : from the forest to the blade scale

    No full text
    Thesis: Ph. D. in Environmental Fluid Mechanics, Massachusetts Institute of Technology, Department of Civil and Environmental Engineering, 2014.116Cataloged from PDF version of thesis.Includes bibliographical references (pages 227-235).From the canopy scale to the blade scale, interactions between fluid motion and kelp produce a wide array of hydrodynamic and scalar transport phenomena. At the kilometer scale of the kelp forest, coastal currents transport nutrients, microorganisms and spores. But, kelp forests exert a drag force on currents, causing the flow to decelerate and divert as it encounters the canopy, affecting the fate of species transported by the current. We identify a dimensionless flow-blockage parameter, based on canopy width and density, that controls both the length of the flow deceleration region and the total flow in the canopy. We further find that shear layers at the canopy edges can interact across the canopy, providing additional exchange between the canopy and the surrounding water. At the sub-meter scale, kelp blades are the photosynthetic engines of kelp forests, but are also responsible for the majority of the fluid drag force on the plants and for acquiring nutrients directly from the surrounding water. These blades are highly flexible structures which move in response to the local fluid forcing. Recent studies documenting changes in blade flexural rigidity in response to changes in flow demonstrate a need for understanding the role blade flexural rigidity plays in setting both drag forces, and nutrient flux at the blade surface. We create a model physical system in which we investigate the role of blade rigidity in setting blade forces and rates of scalar exchange in a vortex street. Using a combination of experimental and theoretical investigations, we find that, broadly, forces are higher for more flexible blades, countering the adage that "going with the flow" is beneficial. Below a critical value of the dimensionless blade rigidity, inertial forces from the rapidly deforming blade become significant, increasing the likelihood of blade failure. Nutrient transport is also affected by blade rigidity. As blades deform, they alter the relative fluid motion at the blade surface, affecting nutrient fluxes. We develop a novel experimental method that simulates nutrient uptake to a blade using the transport of a tracer into polyethylene. Through these experiments and modeling, we demonstrate that increased blade flexibility leads to increased scalar transport. Ultimately, blade flexural rigidity affects both mass and momentum flux.by Jeffrey Tsaros Rominger.Ph. D. in Environmental Fluid Mechanic

    International Impact of COVID-19 on the Diagnosis of Heart Disease

    No full text
    Background: The coronavirus disease 2019 (COVID-19) pandemic has adversely affected diagnosis and treatment of noncommunicable diseases. Its effects on delivery of diagnostic care for cardiovascular disease, which remains the leading cause of death worldwide, have not been quantified. Objectives: The study sought to assess COVID-19's impact on global cardiovascular diagnostic procedural volumes and safety practices. Methods: The International Atomic Energy Agency conducted a worldwide survey assessing alterations in cardiovascular procedure volumes and safety practices resulting from COVID-19. Noninvasive and invasive cardiac testing volumes were obtained from participating sites for March and April 2020 and compared with those from March 2019. Availability of personal protective equipment and pandemic-related testing practice changes were ascertained. Results: Surveys were submitted from 909 inpatient and outpatient centers performing cardiac diagnostic procedures, in 108 countries. Procedure volumes decreased 42% from March 2019 to March 2020, and 64% from March 2019 to April 2020. Transthoracic echocardiography decreased by 59%, transesophageal echocardiography 76%, and stress tests 78%, which varied between stress modalities. Coronary angiography (invasive or computed tomography) decreased 55% (p &lt; 0.001 for each procedure). In multivariable regression, significantly greater reduction in procedures occurred for centers in countries with lower gross domestic product. Location in a low-income and lower–middle-income country was associated with an additional 22% reduction in cardiac procedures and less availability of personal protective equipment and telehealth. Conclusions: COVID-19 was associated with a significant and abrupt reduction in cardiovascular diagnostic testing across the globe, especially affecting the world's economically challenged. Further study of cardiovascular outcomes and COVID-19–related changes in care delivery is warranted

    Reduction of cardiac imaging tests during the COVID-19 pandemic: The case of Italy. Findings from the IAEA Non-invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)

    No full text
    Background: In early 2020, COVID-19 massively hit Italy, earlier and harder than any other European country. This caused a series of strict containment measures, aimed at blocking the spread of the pandemic. Healthcare delivery was also affected when resources were diverted towards care of COVID-19 patients, including intensive care wards. Aim of the study: The aim is assessing the impact of COVID-19 on cardiac imaging in Italy, compare to the Rest of Europe (RoE) and the World (RoW). Methods: A global survey was conducted in May–June 2020 worldwide, through a questionnaire distributed online. The survey covered three periods: March and April 2020, and March 2019. Data from 52 Italian centres, a subset of the 909 participating centres from 108 countries, were analyzed. Results: In Italy, volumes decreased by 67% in March 2020, compared to March 2019, as opposed to a significantly lower decrease (p &lt; 0.001) in RoE and RoW (41% and 40%, respectively). A further decrease from March 2020 to April 2020 summed up to 76% for the North, 77% for the Centre and 86% for the South. When compared to the RoE and RoW, this further decrease from March 2020 to April 2020 in Italy was significantly less (p = 0.005), most likely reflecting the earlier effects of the containment measures in Italy, taken earlier than anywhere else in the West. Conclusions: The COVID-19 pandemic massively hit Italy and caused a disruption of healthcare services, including cardiac imaging studies. This raises concern about the medium- and long-term consequences for the high number of patients who were denied timely diagnoses and the subsequent lifesaving therapies and procedures

    Impact of COVID-19 on Diagnostic Cardiac Procedural Volume in Oceania: The IAEA Non-Invasive Cardiology Protocol Survey on COVID-19 (INCAPS COVID)

    No full text
    Objectives: The INCAPS COVID Oceania study aimed to assess the impact caused by the COVID-19 pandemic on cardiac procedure volume provided in the Oceania region. Methods: A retrospective survey was performed comparing procedure volumes within March 2019 (pre-COVID-19) with April 2020 (during first wave of COVID-19 pandemic). Sixty-three (63) health care facilities within Oceania that perform cardiac diagnostic procedures were surveyed, including a mixture of metropolitan and regional, hospital and outpatient, public and private sites, and 846 facilities outside of Oceania. The percentage change in procedure volume was measured between March 2019 and April 2020, compared by test type and by facility. Results: In Oceania, the total cardiac diagnostic procedure volume was reduced by 52.2% from March 2019 to April 2020, compared to a reduction of 75.9% seen in the rest of the world (p&lt;0.001). Within Oceania sites, this reduction varied significantly between procedure types, but not between types of health care facility. All procedure types (other than stress cardiac magnetic resonance [CMR] and positron emission tomography [PET]) saw significant reductions in volume over this time period (p&lt;0.001). In Oceania, transthoracic echocardiography (TTE) decreased by 51.6%, transoesophageal echocardiography (TOE) by 74.0%, and stress tests by 65% overall, which was more pronounced for stress electrocardiograph (ECG) (81.8%) and stress echocardiography (76.7%) compared to stress single-photon emission computerised tomography (SPECT) (44.3%). Invasive coronary angiography decreased by 36.7% in Oceania. Conclusion: A significant reduction in cardiac diagnostic procedure volume was seen across all facility types in Oceania and was likely a function of recommendations from cardiac societies and directives from government to minimise spread of COVID-19 amongst patients and staff. Longer term evaluation is important to assess for negative patient outcomes which may relate to deferral of usual models of care within cardiology
    corecore