The Institutional Framework of Ethnic Inclusion and Exclusion: A Cross-National Analysis of the Earnings of Foreigners in Germany and Immigrants in Canada

The European social-welfare model differs from the North American individualistic model in the patterns, more than the overall extent, of ethnic inclusion and exclusion. Focussing on foreigners in Germany and immigrants in Canada as illustrative cases, conventional earnings decomposition analysis is extended cross-nationally to highlight institutional effects, using the German Socio-Economic Panel (GSOEP) first wave for 1984, and the 1986 Canadian Census. German education and labor market institutions benefit low-skill migrants, but generate less earnings assimilation. Such assimilation in Canada is greater but varies more by ethnic and racial origins. Institutional frameworks may generate social imperatives shaping patterns of ethnic inclusion and exclusion, quite apart from national policies of citizenship or culture.

Policy Brief No. 14 - The Underutilization of Immigrant Skills: Trends and Policy Issues

Since 1996, the problem of underutilization of immigrant skills in Canada has grown significantly. University-educated immigrants are more numerous, yet our census analysis shows that their access to skilled occupations in the professions and management declined between 1996 and 2006. In these years, the value of work lost to the Canadian economy from immigrant skill underutilization grew from about $4.80 billion to$11.37 billion, annually. Given the significance of immigration for economic development, the evaluation of current policies and consideration of future directions seem urgent

Research Brief No. 9 - Racial Minority Immigrant Offspring Successes in the United States, Canada, and Australia

How well-off are second-generation immigrants in the US, Canada, and Australia? In this study, we examine the successes of immigrant offspring as compared to the respective mainstream populations (third- and higher-generation whites). We also ask whether cross-national differences in the successes of immigrants carry over to their children. We discover that the educational, occupational, and income achievements of second-generation immigrants are very similar for several ethnic groups across these countries. Each country shows common patterns of high achievement for the Chinese and South Asian second generation, less for those of other Asian origins, and still less for Afro-Caribbean blacks

The institutional framework of ethnic inclusion and exclusion: A cross-national analysis of the earnings of foreigners in Germany and immigrants in Canada

The European social-welfare model differs from the North American individualistic model in the patterns, more than the overall extent, of ethnic inclusion and exclusion. Focussing on foreigners in Germany and immigrants in Canada as illustrative cases, conventional earnings decomposition analysis is extended cross-nationally to highlight institutional effects, using the German Socio-Economic Panel (GSOEP) first wave for 1984, and the 1986 Canadian Census. German education and labor market institutions benefit low-skill migrants, but generate less earnings assimilation. Such assimilation in Canada is greater but varies more by ethnic and racial origins. Institutional frameworks may generate social imperatives shaping patterns of ethnic inclusion and exclusion, quite apart from national policies of citizenship or culture

New Directions in Immigration Policy: Canada's Evolving Approach to the Selection of Economic Immigrants

Canada's immigration system is currently undergoing significant change driven by several goals that include (1) a desire to improve the economic outcomes of entering immigrants; (2) an attempt to better respond to short-term regional labor market shortages often associated with commodity booms, and (3) a desire to shift immigration away from the three largest cities to other regions of the country. These goals reflect the implementation of new immigration programs in the 2000s. The paper discusses the recent changes to Canadian immigration policy, examines preliminary evaluations of the new programs and discusses potential future issues emanating from the changes

Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR, and SPINK1 variants were associated with pancreatitis risk. We now report two significant genome-wide associations identified and replicated at PRSS1-PRSS2 (1×10-12) and x-linked CLDN2 (p < 1×10-21) through a two-stage genome-wide study (Stage 1, 676 cases and 4507 controls; Stage 2, 910 cases and 4170 controls). The PRSS1 variant affects susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous (or hemizygous male) CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men – male hemizygous frequency is 0.26, female homozygote is 0.07

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

We identified rare coding variants associated with Alzheimer’s disease (AD) in a 3-stage case-control study of 85,133 subjects. In stage 1, 34,174 samples were genotyped using a whole-exome microarray. In stage 2, we tested associated variants (P<1×10-4) in 35,962 independent samples using de novo genotyping and imputed genotypes. In stage 3, an additional 14,997 samples were used to test the most significant stage 2 associations (P<5×10-8) using imputed genotypes. We observed 3 novel genome-wide significant (GWS) AD associated non-synonymous variants; a protective variant in PLCG2 (rs72824905/p.P522R, P=5.38×10-10, OR=0.68, MAFcases=0.0059, MAFcontrols=0.0093), a risk variant in ABI3 (rs616338/p.S209F, P=4.56×10-10, OR=1.43, MAFcases=0.011, MAFcontrols=0.008), and a novel GWS variant in TREM2 (rs143332484/p.R62H, P=1.55×10-14, OR=1.67, MAFcases=0.0143, MAFcontrols=0.0089), a known AD susceptibility gene. These protein-coding changes are in genes highly expressed in microglia and highlight an immune-related protein-protein interaction network enriched for previously identified AD risk genes. These genetic findings provide additional evidence that the microglia-mediated innate immune response contributes directly to AD development

Non-Standard Errors

In statistics, samples are drawn from a population in a data-generating process (DGP). Standard errors measure the uncertainty in estimates of population parameters. In science, evidence is generated to test hypotheses in an evidence-generating process (EGP). We claim that EGP variation across researchers adds uncertainty: Non-standard errors (NSEs). We study NSEs by letting 164 teams test the same hypotheses on the same data. NSEs turn out to be sizable, but smaller for better reproducible or higher rated research. Adding peer-review stages reduces NSEs. We further find that this type of uncertainty is underestimated by participants