418 research outputs found
Arbitrary qubit transformations on tuneable Rashba rings
An exact solution is presented for the time-dependent wave function of an initial ground-state Kramers-doublet qubit that is driven around a quantum ring. We show that the initial qubit may be transformed to an arbitrary point on the Bloch sphere for an integral number of revolutions around the ring. Full coverage of the Bloch sphere is achieved by dividing the total rotation into segments, changing the rotation axis after each segment by an adiabatic shift in the Rashba spin-orbit interaction. Prospects and challenges for possible realizations are discussed for which rings based on InAs quantum wires are promising candidates
Parent-progeny relationships and genotype X environment effects for factors associated with grass tetany and forage quality in Russian Wildrye
Grass tetany (hypomagnesemia) has caused severe economic losses
in ruminant animals grazing cool-season grasses, including Russian
wildrye [Psathyrostachys juncea (Fisch.) Nevski]. The malady has
been associated with deficiencies in Mg, Ca, and carbohydrates, and
high levels of K. The K/(Ca + Mg) ratio (KRAT), expressed as moles
of charge, is often used to express the grass tetany potential of forage.
Development and use of new cultivars with an improved balance of
the associated minerals would be an economical approach to reduce
the incidence of grass tetany. Objectives of this study were to characterize
the genetic variability, genotype by environment interactions,
and intercharacter relationships for P, K, Ca, Mg, KRAT, crude protein
(CP), neutral detergent fiber (NDF), and in vitro dry matter
digestibility (IVDMD), among 21 clonal lines of Russian wildrye and
their polycross progenies. Evaluations were made for 2 yr at three
diverse locations in the USA and Canada. The clonal lines were
derived from cultivars and plant introductions. Although the clone x
location interaction was usually significant, differences among the
clonal lines were significant for K, Ca, Mg, and KRAT, and three
forage quality estimates of CP, NDF, and true IVDMD. Although
the magnitude of the genetic variability among the progenies was
substantially less than that found among the clonal lines, we conclude
that the grass tetany potential, CP, NDF, IVDMD, and P concentration
of this breeding population can be altered through breeding.
Opportunities for genetic improvement in forage quality were particularly
favorable for CP. Genetic correlations among the clonal lines
suggested that selection for higher levels of CP would be accompanied
by increased K, Ca, Mg, and IVDMD and reduced KR AT and NDF
Data Descriptor : Collocated observations of cloud condensation nuclei, particle size distributions, and chemical composition
Cloud condensation nuclei (CCN) number concentrations alongside with submicrometer particle number size distributions and particle chemical composition have been measured at atmospheric observatories of the Aerosols, Clouds, and Trace gases Research InfraStructure (ACTRIS) as well as other international sites over multiple years. Here, harmonized data records from 11 observatories are summarized, spanning 98,677 instrument hours for CCN data, 157,880 for particle number size distributions, and 70,817 for chemical composition data. The observatories represent nine different environments, e.g., Arctic, Atlantic, Pacific and Mediterranean maritime, boreal forest, or high alpine atmospheric conditions. This is a unique collection of aerosol particle properties most relevant for studying aerosol-cloud interactions which constitute the largest uncertainty in anthropogenic radiative forcing of the climate. The dataset is appropriate for comprehensive aerosol characterization (e.g., closure studies of CCN), model-measurement intercomparison and satellite retrieval method evaluation, among others. Data have been acquired and processed following international recommendations for quality assurance and have undergone multiple stages of quality assessment.Peer reviewe
Comment letters to the National Commission on Commission on Fraudulent Financial Reporting, 1987 (Treadway Commission) Vol. 1
https://egrove.olemiss.edu/aicpa_sop/1661/thumbnail.jp
AI is a viable alternative to high throughput screening: a 318-target study
: High throughput screening (HTS) is routinely used to identify bioactive small molecules. This requires physical compounds, which limits coverage of accessible chemical space. Computational approaches combined with vast on-demand chemical libraries can access far greater chemical space, provided that the predictive accuracy is sufficient to identify useful molecules. Through the largest and most diverse virtual HTS campaign reported to date, comprising 318 individual projects, we demonstrate that our AtomNet® convolutional neural network successfully finds novel hits across every major therapeutic area and protein class. We address historical limitations of computational screening by demonstrating success for target proteins without known binders, high-quality X-ray crystal structures, or manual cherry-picking of compounds. We show that the molecules selected by the AtomNet® model are novel drug-like scaffolds rather than minor modifications to known bioactive compounds. Our empirical results suggest that computational methods can substantially replace HTS as the first step of small-molecule drug discovery
Azimuthal anisotropy of charged jet production in root s(NN)=2.76 TeV Pb-Pb collisions
We present measurements of the azimuthal dependence of charged jet production in central and semi-central root s(NN) = 2.76 TeV Pb-Pb collisions with respect to the second harmonic event plane, quantified as nu(ch)(2) (jet). Jet finding is performed employing the anti-k(T) algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero nu(ch)(2) (jet) is observed in semi-central collisions (30-50% centrality) for 20 <p(T)(ch) (jet) <90 GeV/c. The azimuthal dependence of the charged jet production is similar to the dependence observed for jets comprising both charged and neutral fragments, and compatible with measurements of the nu(2) of single charged particles at high p(T). Good agreement between the data and predictions from JEWEL, an event generator simulating parton shower evolution in the presence of a dense QCD medium, is found in semi-central collisions. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).Peer reviewe
Forward-central two-particle correlations in p-Pb collisions at root s(NN)=5.02 TeV
Two-particle angular correlations between trigger particles in the forward pseudorapidity range (2.5 2GeV/c. (C) 2015 CERN for the benefit of the ALICE Collaboration. Published by Elsevier B. V.Peer reviewe
Event-shape engineering for inclusive spectra and elliptic flow in Pb-Pb collisions at root(NN)-N-S=2.76 TeV
Peer reviewe
Addressing the climate challenge
In 2021, colleagues from across the University of Birmingham community were invited to write articles about topics relevant to the COP26 climate change summit.
In this series of articles, experts from across many different disciplines provide new insight and evidence on how we might all understand and tackle climate change
- …