48 research outputs found
Theory of a Scanning Tunneling Microscope with a Two-Protrusion Tip
We consider a scanning tunneling microscope (STM) such that tunneling occurs
through two atomically sharp protrusions on its tip. When the two protrusions
are separated by at least several atomic spacings, the differential conductance
of this STM depends on the electronic transport in the sample between the
protrusions. Furthermore two-protrusion tips commonly occur during STM tip
preparation. We explore possible applications to probing dynamical impurity
potentials on a metallic surface and local transport in an anisotropic
superconductor.Comment: revtex, 11 pages, 6 figures upon reques
Quantitative LSPR Imaging for Biosensing with Single Nanostructure Resolution
AbstractLocalized surface plasmon resonance (LSPR) imaging has the potential to map complex spatio-temporal variations in analyte concentration, such as those produced by protein secretions from live cells. A fundamental roadblock to the realization of such applications is the challenge of calibrating a nanoscale sensor for quantitative analysis. Here, we introduce a new, to our knowledge, LSPR imaging and analysis technique that enables the calibration of hundreds of individual gold nanostructures in parallel. The calibration allowed us to map the fractional occupancy of surface-bound receptors at individual nanostructures with nanomolar sensitivity and a temporal resolution of 225 ms. As a demonstration of the technique’s applicability to molecular and cell biology, the calibrated array was used for the quantitative LSPR imaging of anti-c-myc antibodies harvested from a cultured 9E10 hybridoma cell line without the need for further purification or processing
Local Electronic Structure of a Single Magnetic Impurity in a Superconductor
The electronic structure near a single classical magnetic impurity in a
superconductor is determined using a fully self-consistent Koster-Slater
algorithm. Localized excited states are found within the energy gap which are
half electron and half hole. Within a jellium model we find the new result that
the spatial structure of the positive-frequency (electron-like) spectral weight
(or local density of states), can differ strongly from that of the negative
frequency (hole-like) spectral weight. The effect of the impurity on the
continuum states above the energy gap is calculated with good spectral
resolution for the first time. This is also the first three-dimensional
self-consistent calculation for a strong magnetic impurity potential.Comment: 13 pages, RevTex, change in heuristic picture, no change in numerical
result
Koinonia
Best Practices FeaturesStudents of Concern Committee: Coordinating Care, Connie Horton and Mark Davis
Want to Change Student Culture on Your Campus? Do the CORE!, Eric Lowdermilk
Spotlight FeaturesYou Only Get 1 Up, Justin Heth and Caleb Farmer
The Season, Sharon Virkler
Book ReviewsThe Future of Christian Learning: An Evangelical and Catholic Dialogue (by Mark Noll and James Turner), reviewed by Philip D. Byers
Restoring Rebecca: A Story of Traumatic Stress, Caregiving and the Unmasking of a Superhero (by Christopher Marchand), reviewed by David M. Johnstone
A Review of Culture Making: Recovering our Creative Calling (by Andy Crouch), reviewed by Jeff Rioux
Revisiting How Minority Students Experience College: Implications for Planning and Policy (by LKemuel Watson, Melvin Terrell, Doris Wright, Fred Bonner II, Michael Cuyjet, James Gold, Donna Rudy and Dawn Person), reviewed by Joshua Canada
Excerpts from Breathe: Finding Freedom to Thrive in Relationships after Childhood Sexual Abuse, Nicole Braddock Bromley
ReflectionsMy Journey into Student Affairs, Kim Stave
FeaturesThe President\u27s Corner
Editor\u27s Deskhttps://pillars.taylor.edu/acsd_koinonia/1079/thumbnail.jp
Spin diffusion in doped semiconductors
The behavior of spin diffusion in doped semiconductors is shown to be
qualitatively different than in undoped (intrinsic) ones. Whereas a spin packet
in an intrinsic semiconductor must be a multiple-band disturbance, involving
inhomogeneous distributions of both electrons and holes, in a doped
semiconductor a single-band disturbance is possible. For n-doped nonmagnetic
semiconductors the enhancement of diffusion due to a degenerate electron sea in
the conduction band is much larger for these single-band spin packets than for
charge packets, and can exceed an order of magnitude at low temperatures even
for equilibrium dopings as small as 10^16 cm^-3. In n-doped ferromagnetic and
semimagnetic semiconductors the motion of spin packets polarized antiparallel
to the equilibrium carrier spin polarization is predicted to be an order of
magnitude faster than for parallel polarized spin packets. These results are
reversed for p-doped semiconductors.Comment: 8 pages, 4 figure
Local Electronic Structure of Defects in Superconductors
The electronic structure near defects (such as impurities) in superconductors
is explored using a new, fully self-consistent technique. This technique
exploits the short-range nature of the impurity potential and the induced
change in the superconducting order parameter to calculate features in the
electronic structure down to the atomic scale with unprecedented spectral
resolution. Magnetic and non-magnetic static impurity potentials are
considered, as well as local alterations in the pairing interaction. Extensions
to strong-coupling superconductors and superconductors with anisotropic order
parameters are formulated.Comment: RevTex source, 20 pages including 22 figures in text with eps
Clinical Sequencing Exploratory Research Consortium: Accelerating Evidence-Based Practice of Genomic Medicine
Despite rapid technical progress and demonstrable effectiveness for some types of diagnosis and therapy, much remains to be learned about clinical genome and exome sequencing (CGES) and its role within the practice of medicine. The Clinical Sequencing Exploratory Research (CSER) consortium includes 18 extramural research projects, one National Human Genome Research Institute (NHGRI) intramural project, and a coordinating center funded by the NHGRI and National Cancer Institute. The consortium is exploring analytic and clinical validity and utility, as well as the ethical, legal, and social implications of sequencing via multidisciplinary approaches; it has thus far recruited 5,577 participants across a spectrum of symptomatic and healthy children and adults by utilizing both germline and cancer sequencing. The CSER consortium is analyzing data and creating publically available procedures and tools related to participant preferences and consent, variant classification, disclosure and management of primary and secondary findings, health outcomes, and integration with electronic health records. Future research directions will refine measures of clinical utility of CGES in both germline and somatic testing, evaluate the use of CGES for screening in healthy individuals, explore the penetrance of pathogenic variants through extensive phenotyping, reduce discordances in public databases of genes and variants, examine social and ethnic disparities in the provision of genomics services, explore regulatory issues, and estimate the value and downstream costs of sequencing. The CSER consortium has established a shared community of research sites by using diverse approaches to pursue the evidence-based development of best practices in genomic medicine