Mast Cell Tumour in a Dog and Its Surgical Management

Abstract An 8-year-old male Labrador dog was presented with a history of inappetence, occasional bloody diarrhoea and two ulcerated pea-nut sized swelling in the groin region. On the basis of complete blood cell count and cytological examination of the tumour aspirate it was diagnosed as a case of mast cell tumour. Under general anaesthesia the tumour nodules were excised and three doses of vincrystine sulphate were given at recommended dose with dextrose normal saline. Post-operatively antibiotics, analgesics and supportive therapy were followed and the dog recovered well without any recurrence

ANALYSIS OF MINERAL COMPOSITION OF CANINE UROLITHS - A RETROSPECTIVE STUDY

Twenty six cases were studied for analysis of uroliths surgically retrieved from canine of different age, sex, body weight, geographical location and nutritional status. The uroliths were quantitatively analyzed by atomic absorption spectrophotometric analysis (AAS), Flame photometry and calcium and phosphorus estimation. The struvite stones were found to be more predominant in number, than other type of uroliths

SURGICAL MANAGEMENT OF NECK TUMOURS IN DOGS: CASE REPORTS

The present study was conducted on two dogs, one pug and one mongrel presented with the history of swelling at the base of neck. In one of the cases there was ulceration of the skin around the enlarged mass and in the second case there was gradual increase in size of the mass along with bending of neck to one side and reduced appetite. Further, the physical and radiographical examinations were conducted that confirmed the occurrence of tumour in both the cases. Under physical restraint and general anaesthesia the excision of the tumour mass was done along with the proper control of haemorrhage. Both the cases recovered well without any critical symptoms there of up to one year after surgery

Autologous stem cell therapy to treat chronic ulcer in heifer- A case study

Aim: The study was conducted to reveal the efficacy of Bone marrow derived mesenchymal stem cells (BM-MSCs) based therapy in healing of chronic non-healing and ulcerative wound in bovine species. Materials and Methods: One 2 years old Jersey heifer affected with chronic ulcerative wound involving full thickness skin and under lying muscle at dorsal side of lumbar region since four months at the time of presentation. Bone marrow was collected from tibia, cultured and grown and after achievement of optimum confluence it was applied at the site. Different parameters of clinical, physiological, haematological, biochemical, histochemical, histological, tensile strength and photographic evaluations were done during the study period. Results: The estimated values of above mentioned parameters on zero day and after healing (18 days) showed significant difference (P<0.05) in relation to collagen content, tensile strength and physical characteristics of wound like extent of wound, size of wound, type of exudates and photography. But clinical, haematological and biochemical data showed no significant difference. Conclusion: The BM-MSCs were the main pioneers to bring the chronic ulcerative wound towards healing. The procedure is simple, safe and effective in bringing out healing without showing any adverse effect on host. [Vet World 2012; 5(12.000): 771-774

Clinical evaluation of total intravenous anaesthesia using xylazine or dexmedetomidine with propofol in surgical management of canine patients

Aim: The aim was to evaluate and compare the clinico-physiological, hemodynamic and hematobiochemical effects in response to different total intravenous anaesthesia techniques using xylazine or dexmedetomidine with propofol in canine patients. Materials and Methods: Under a prospective randomized blinded clinical study, 12 apparently healthy adult dogs (14.27±3.2 kg) divided into two groups (n=6). Animals were administered with xylazine (0.5 mg/kg body weight IV) in X group or, dexmedetomidine (10 μg/kg body weight IV) in D group and propofol (as IV bolus till the induction and continuous IV infusion for maintenance). Clinical reflexes, physiological, hemodynamic parameters, were recorded at 5-min intervals. Blood was collected at zero, 30 and 60 min after initial injection for hematobiochemical evaluation. Statistical analysis was performed using analysis of variance, Duncan’s multiple range tests, paired - t-test and Kruskal–Wallis one-way test. Results: Animals showed quicker attenuation of all clinical reflexes in group D. Induction doses of propofol were 3.17±0.21 and 2.72±0.15 mg/kg and rate of infusion of propofol for maintenance of anaesthesia were 0.33±0.02 mg/kg/min and 0.35±0.02 mg/kg/min respectively in group X and D. Recovery was quicker in group D. There were no significant statistical differences in physiological, hemodynamic and hematobiochemical parameters in both the groups. There were no adverse effects after recovery. Conclusion: Both anesthetic protocols provided satisfactory immobilization, but dexmedetomidine-propofol combination may be preferred owing to slightly better degree of basal anaesthesia, lesser doses of propofol required for induction and maintenance of anaesthesia along with a lesser degree of respiratory depression. However, there was no clear preference for either of the protocol, and both appear suitable for canines

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Not AvailableIndia has the largest burden of drug‑resistant organisms compared with other countries around the world, including multiresistant and extremely drug‑resistant tuberculosis and resistant Gram‑negative and Gram‑positive bacteria. Antibiotic resistant bacteria are found in all living hosts and in the environment and move between hosts and ecosystems. An intricate interplay of infections, exposure to antibiotics, and disinfectants at individual and community levels among humans, animals, birds, and fishes triggers evolution and spread of resistance. The One Health framework proposes addressing antibiotic resistance as a complex multidisciplinary problem. However, the evidence base in the Indian context is limited.Not Availabl