Additional file 2: of Validation and psychometric analysis of the Internet Addiction Test in Spanish among college students

Spanish version of IAT. (PDF 7 kb

Characteristics of the mothers and their newborn, depending on their country of origin.

<p>^a Standard Deviation.</p><p>^b % Valid when missing.</p><p>^c Insufficient Oral Spanish language skill.</p><p>^d Insufficient Reading Spanish skills.</p><p>^e Insufficient Writing Spanish skills.</p><p>^f Referral to social worker because of Social Risk factor detection.</p><p>^g Prenatal care as assessed by KI: Adequate: first consultation before week 14 and at least 9 consultations during gestation. Inadequate: start of care after week 28, or less than 4 consultations during gestation. Intermediate: the other combinations.</p><p>^h Prenatal care as assessed by OI: Adequate: all 7 indicators of the Spanish Health Service pregnancy care protocol met. Inadequate: ≥4 indicators unmet. Intermediate: 1–3 indicators unmet.</p><p>*p ≥ 0.01 - < 0.05</p><p>** p ≥ 0.001 - < 0.01</p><p>*** p < 0.001</p><p>Cantabria (Spain): African immigrants and Spanish women 2007–2010.</p

Crude and adjusted associations between the immigrant status, other predefined variables (social risk factors and compliance with prenatal care), and the risk of neonatal morbidity (low weight).

<p>^a Newborn less than 2,500 grams at birth</p><p>^b Odds Ratio and 95% Confidence Intervals. ORc denotes “crude Odds ratio” = the basic regression model adding only the frequency matching variable: Primary Health Center (PHC).</p><p>^c ORa1 denotes “adjusted” OR adding to the basic model: immigrant status and social risk factors.</p><p>^d ORa2 denotes “adjusted” OR adding to the basic model: immigrant status and prenatal care.</p><p>^e ORa3 denotes “adjusted” OR adding to the basic model: immigrant status, social risk factors, and prenatal care.</p><p>^f ORa4 denotes “adjusted” OR adding to the basic model: immigrant status, social risk factors, prenatal care, maternal age at delivery (continuous), and number of previous pregnancies (continuous).</p><p>^g African immigran women (Sub-Saharan and North-African combined)</p><p>^h Referral to a social worker because of social risk factor detection.</p><p>ⁱ Prenatal care as assessed by KI: Adequate: first consultation before week 14 and at least 9 consultations during gestation. Inadequate: start of care after week 28, or less than 4 consultations during gestation. Intermediate: the other combinations.</p><p>^j Prenatal care as assessed by OI: Adequate: all 7 indicators of the Spanish Health Service pregnancy care protocol met. Inadequate: ≥4 indicators unmet. Intermediate: 1–3 indicators unmet.</p><p>Cantabria (Spain): African immigrants and Spanish women 2007–2010.</p

Comparison of carotid artery intima media thickness (IMT) according to <i>IFNG</i> rs2430561 variant.

<p>Comparison of carotid artery intima media thickness (IMT) according to <i>IFNG</i> rs2430561 variant.</p

IFN-γ serum levels (pg/ml) in a subsample of patients (n = 153) with RA stratified according to the presence or absence of CV events.

*<p>Analyses adjusted for gender, age at RA diagnosis, follow-up time from the disease diagnosis, presence or absence of shared epitope, and classic cardiovascular risk factors.</p

Differences in genotype and allele frequencies of <i>IFNG</i> rs2430561 functional gene variant between RA patients with CV events <i>versus</i> patients without CV events.

<p>CV: Cardiovascular. Except for OR, values are number (%). OR [95% CI]: Odds Ratio with 95% Confidence Interval.</p

IFN-γ levels (pg/ml) in patients without CV events (left) or with CV events (right) according to genotypes and allele distribution of rs3430561 polymorphism.

<p>IFN-γ levels (pg/ml) in patients without CV events (left) or with CV events (right) according to genotypes and allele distribution of rs3430561 polymorphism.</p

Comparison of carotid intima-media thickness (cIMT) according to <i>CD40</i> rs1883832, rs4810485 and rs1535045 alleles in an adjusted ANCOVA model.

*<p>Analyses adjusted for sex, age at rheumatoid arthritis diagnosis, follow-up time, and traditional cardiovascular risk factors.</p>**<p>Conditional analysis of the rs1883832 and rs1535045 <i>CD40</i> gene variants.</p>†<p>Analyses adjusted for sex, age at rheumatoid arthritis diagnosis, follow-up time, traditional cardiovascular risk factors and anti-CCP status: <i>p</i> = 0.82 and 0.0047 for rs1883832 and rs1535045, respectively.</p

Comparison of IFN-γ levels in patients with or without CV events according to <i>IFNG</i> rs2430561 alleles in an adjusted ANCOVA model.

*<p>Analyses adjusted for gender, age at rheumatoid arthritis diagnosis, follow-up time from disease diagnosis, and classic cardiovascular risk factors: hypertension, diabetes mellitus, dyslipidemia, obesity and smoking habit.</p

Clinical and demographic characteristics of rheumatoid arthritis (RA) patients included in the study, stratified by gender or by Cardiovascular events.

<p>Except where indicated otherwise, values are n (%). IQR: Interquartile Range. Anti-CCP: anti-Cyclic Citrullinated Peptide antibodies.</p>*<p>A patient was considered to have a cerebrovascular accident when he/she had a stroke and/or transient ischemic attacks (TIAs). Strokes were classified according to their clinical features and they were confirmed by computed tomography and/or magnetic resonance imaging. TIAs were diagnosed if the symptoms were self-limited in less than 24 hours, without residual neurological damage <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0049214#pone.0049214-GonzlezGay2" target="_blank">[41]</a>.</p>**<p>Smoking habit encompassed to those patients who smoked at the time of disease diagnosis, during the follow-up or who had smoked within the 10 years before the onset of RA symptoms or the disease diagnosis.</p