DYNAMICS OF RODENT ASSEMBLAGES INHABITING ABANDONED PETROLEUM LANDFARMS IN OKLAHOMA

Studies on the effects of anthropogenic contamination on wildlife have largely been focused at the individual level. Biomarkers have been used to monitor changes in the health of individuals exposed to contaminants; however, little attention has been given to the effects of chronic exposure at the population or community levels. We studied rodent assemblages from uncontaminated (reference) sites (n 5 5) and abandoned petrochemical landfarms (n 5 5) in Oklahoma to investigate potential alterations in community structure and composition. Rodent assemblages inhabiting landfarms had lower species diversity, lower richness, and a more even distribution of individuals across species. Reference sites showed typical rodent assemblage structure dominated by hispid cotton rats (Sigmodon hispidus) and fulvous harvest mice (Reithrodontomys fulvescens). Assemblages inhabiting landfarms also were dominated by cotton rats; however, harvest mice were replaced by deer mice (Peromyscus maniculatus) on two landfarms. Contaminated sites also were characterized by an increase in house mice (Mus musculus) and an absence of voles (Microtus spp.). Although landfarms tended to have lower cotton rat densities, we could not separate the effects of contamination from increased bare ground associated with landfarms. The results of this study suggest that rodent assemblages were different on landfarms, when compared with reference sites. However, no direct link between site contamination and rodent community structure could be established

An energy-momentum consistent time integration scheme based on a mixed framework for non-linear electro-elastodynamics

The objective of the present work is the introduction of new mixed variational principles for EM time integrators in electromechanics, hence bridging the gap between the previous work presented by the authors in References [11] and [1], opening up the possibility to a variety of new Finite Element implementations

Decay of an active GPCR: Conformational dynamics govern agonist rebinding and persistence of an active, yet empty, receptor state

G protein-coupled receptors (GPCRs) represent a major pharmaceutical drug target. However, one exception has been the visual photoreceptor rhodopsin, long considered “different” due to its covalently bound, light-sensitive retinal ligands. Here we demonstrate that, in contrast to prior assumptions, release of the agonist all-trans retinal (ATR) is not an irreversible process. Instead, during decay of the active species, ATR can rebind any rhodopsin remaining in an active-like conformation, and this active-like state can transiently persist even after agonist dissociation. These insights demonstrate rhodopsin behaves like other diffusible ligand-binding GPCRs and raise the possibility of treating rhodopsin by pharmaceutical agents