39 research outputs found

    The "Hurried" Child: Myth vs. Reality

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    Based on a national survey and a qualitative study, examines the view that children are overscheduled with activities to the point of stress. Looks at how busy children are, how social class affects participation, and which children show stress symptoms

    Recruitment of Dental Hygiene Students from Underrepresented Minority Groups: A National Survey of U.S. Dental Hygiene Programs

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153698/1/jddj0022033720157910tb06010x.pd

    Interprofessional Education in U.S. Dental Hygiene Programs: A National Survey

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153608/1/jddj0022033720157911tb06024x.pd

    LGBT Coverage in U.S. Dental Schools and Dental Hygiene Programs: Results of a National Survey

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153556/1/jddj0022033720168012tb06231x.pd

    Effects of triclosan on host response and microbial biomarkers during experimental gingivitis

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    AimThis exploratory randomized, controlled clinical trial sought to evaluate anti‐inflammatory and ‐microbial effects of triclosan during experimental gingivitis as assessed by host response biomarkers and biofilm microbial pathogens.Materials and MethodsThirty participants were randomized to triclosan or control dentifrice groups who ceased homecare for 21 days in an experimental gingivitis (EG) protocol. Plaque and gingival indices and saliva, plaque, and gingival crevicular fluid (GCF) were assessed/collected at days 0, 14, 21 and 35. Levels and proportions of 40 bacterial species from plaque samples were determined using checkerboard DNA‐DNA hybridization. Ten biomarkers associated with inflammation, matrix degradation, and host protection were measured from GCF and saliva and analysed using a multiplex array. Participants were stratified as “high” or “low” responders based on gingival index and GCF biomarkers and bacterial biofilm were combined to generate receiver operating characteristic curves and predict gingivitis susceptibility.ResultsNo differences in mean PI and GI values were observed between groups and non‐significant trends of reduction of host response biomarkers with triclosan treatment. Triclosan significantly reduced levels of A. actinomycetemcomitans and P. gingivalis during induction of gingivitis.ConclusionsTriclosan reduced microbial levels during gingivitis development (ClinicalTrials.gov NCT01799226).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/134115/1/jcpe12519.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/134115/2/jcpe12519_am.pd

    Clinical, microbiological, and salivary biomarker profiles of dental implant patients with type 2 diabetes

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    Objective Regulators of peri‐implant bone loss in patients with diabetes appear to involve multiple risk factors that have not been clearly elucidated. This study was conducted to explore putative local etiologic factors on implant bone loss in relation to type 2 diabetes mellitus, including clinical, microbial, salivary biomarker, and psychosocial factors. Materials and methods Thirty‐two subjects (divided into type 2 diabetes mellitus and non‐diabetic controls), having at least one functional implant and six teeth, were enrolled in a 1‐year longitudinal investigation. Analyses of clinical measurements and standardized intra‐oral radiographs, saliva and serum biomarkers (via protein arrays for 20 selected markers), and plaque biofilm (via q PCR for eight periodontal pathogens) were performed at baseline and 1 year. In addition, the subjects were asked to respond to questionnaires to assess behavioral and psychosocial variables. Results There was a significant increase from baseline to 1 year in the probing depth of implants in the diabetes group (1.95 mm to 2.35 mm, P  = 0.015). The average radiographic bone loss during the study period marginally increased at dental implants compared to natural teeth over the study period (0.08 mm vs. 0.05 mm; P  = 0.043). The control group harbored higher levels of T reponema denticola at their teeth at baseline ( P  = 0.046), and the levels of the pathogen increased significantly over time around the implants of the same group ( P  = 0.003). Salivary osteoprotegerin ( OPG ) levels were higher in the diabetes group than the control group at baseline only; in addition, the salivary levels of IL ‐4, IL ‐10, and OPG associated with host defense were significantly reduced in the diabetes group ( P  = 0.010, P  = 0.019, and P  = 0.024), while controls showed an increase in the salivary OPG levels ( P  = 0.005). For psychosocial factors, there were not many significant changes over the observation period, except for some findings related to coping behaviors at baseline. Conclusions The study suggests that the clinical, microbiological, salivary biomarker, and psychosocial profiles of dental implant patients with type 2 diabetes who are under good metabolic control and regular maintenance care are very similar to those of non‐diabetic individuals. Future studies are warranted to validate the findings in longer‐term and larger clinical trials ( ClinicalTrials.gov # NCT00933491).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/107497/1/clr12139.pd

    Bacterial and Salivary Biomarkers Predict the Gingival Inflammatory Profile

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141936/1/jper0632-sup-0001.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141936/2/jper0632-sup-0002.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141936/3/jper0079.pd
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