(A) The association signal between total serum ALP and the ABO blood locus. (B): The association of lead SNPs at the ABO locus with serum ALP and their relation with ABO tag SNPs (rs8176746, rs8176704, rs505922); A significant drop in association effect in lead SNPs after controlling for ABO-tag SNPs are shown (red and black dots represent before and after conditional analyses respectively).

<p>(A) The association signal between total serum ALP and the ABO blood locus. (B): The association of lead SNPs at the ABO locus with serum ALP and their relation with ABO tag SNPs (rs8176746, rs8176704, rs505922); A significant drop in association effect in lead SNPs after controlling for ABO-tag SNPs are shown (red and black dots represent before and after conditional analyses respectively).</p

Quantitative and case-control association result of top SNPs in UGT1A1 for total serum bilirubin levels in pediatric and adult subgroups.

<p>*Map Position: NCBI build 37.</p><p>†linear regression association test.</p><p>‡Chi-square test.</p><p>Quantitative and case-control association result of top SNPs in UGT1A1 for total serum bilirubin levels in pediatric and adult subgroups.</p

(A and B) Manhattan plot and Q–Q plot of genome-wide markers for total serum bilirubin in 3294 European samples respectively.

<p>(A and B) Manhattan plot and Q–Q plot of genome-wide markers for total serum bilirubin in 3294 European samples respectively.</p

A schematic representation of association map at UGT1A region for total serum bilirubin.

<p>The TA repeat location is shown with vertical line.</p

A GWAS Study on Liver Function Test Using eMERGE Network Participants - Table 4

<p>A GWAS Study on Liver Function Test Using eMERGE Network Participants - Table 4 </p

The LD structure between markers in peak association signals.

<p>r2 = correlation coefficient as a measure of linkage disequilibrium.</p