Prediction of protein coding regions in unannotated DNA sequences using an inhomogeneous Markov model of genetic information encoding

Ph.D.Mark Borodovsk

RNAi-mediated rheostat for dynamic control of AAV-delivered transgenes

Here the authors propose an RNA interference-based switch for dynamic control of AAV transgene expression. In this approach, transgene expression may be silenced by RNAi and subsequently recovered using REVERSIR oligonucleotides