President-Elect's Message: Internationalization of the International Association for Dental Research

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Greetings and Opening Remarks

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A Phenomenon in the Trigeminal System

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Ultrastructure of Odontoblasts in Dentinal Tubules of Mice

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Microradiographic and microhardness studies of developing enamel

This study was undertaken on human and Rhesus monkey enamel using three methods of analysis to gain information concerning the pattern of enamel calcification: (1) microhardness pattern of enamel mineralization; (2) microradiography; and (3) plastic substitution studies. Halves of teeth were selected and tested on a Tukon Microhardness Tester with a Knoop Diamond Indentor. The other half of each tooth was further sectioned. Several sections from each tooth were ground to less than 150 [mu] in thickness and microradiographs were taken; the remainder were used for the substitution studies. All organic tissue and water were removed from the sections and replaced with plastic. Decalcification of these sections revealed areas of low and high organic and water content. It was found that mineralization of the enamel matrix begins at the dentino-enamel junction and proceeds peripherally, thus following the incremental pattern of formation of the enamel matrix. Final calcification is completed after the matrix is completely deposited and follows this same pattern from the dentino-enamel junction peripherally. The enamel rod matrix becomes calcified before the interrod substance, the latter thus presenting pathways for diffusion of tissue fluid containing calcium and phosphate ions, during the mineralization process. The interrod substance is the first area of enamel to be altered in dental caries. Thus the steps in enamel destruction are in reverse order to those in enamel formation.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/32334/1/0000404.pd

Demonstration of Multiple Esterases of the Human Dental Pulp After Electrophoresis in Starch and Acrylamide Gels

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Ultrastructure of Capillaries in the Odontoblastic Layer

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Ultrastructure of a Presumptive Golgi-Mazzoni Receptor in the Periodontal Ligament in Mice

A variety of encapsulated and free periodontal nerve endings have been described in extracted human teeth (Griffin and Harris, Australian DJ, 19:255-59, 1974; Harris and Griffin, Australian DJ, 19:174-81, 326-37, 1974), and in mouse molars with intact surrounding periodontium (Corpron et al., J Dent Res, 53-75, 1974; Avery et al., J Dent Res, 54:92, 1975; Corpron et at. J Dent Res, 57:B224, 1977).Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/68300/2/10.1177_00220345800590020501.pd

Ultrastructure of Capillaries in Mouse Periodontium

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Histopathologic evaluation of the effects of four calcium hydroxide liners on monkey pulps

Pulpal response of four calcium hydroxide liners, MPC 10®, MPC 12®, Dycal® and Pulpdent® were tested on primary and permanent teeth with zinc oxide and eugenol (ZOE) and silicate as controls. Responses of the pulps were evaluated in Rhesus monkeys, utilizing Class V cavity preparations at 3 days, 5 and 8 weeks. An equivalent number of anterior and posterior teeth were studied for all compounds. The Ca(OH) 2 liners, zinc oxide and eugenol (ZOE) and silicate controls were placed in 80 primary and 80 permanent teeth. Following perfusions the teeth were prepared utilizing routine histological procedures. The 3 day response of the calcium hydroxides was moderate with some disruption in the odontoblasts, vacuolization and mild inflammation underlying the cavity except Pulpdent which was more severe. At 5 weeks a decrease in inflammatory response and the formation of reparative dentin was similar for all calcium hydroxides tested at this time period. At 8 weeks more reparative dentin was noted with slight to moderate pulpal responses. At all time periods ZOE produced the least pulpal response while silicate produced the most severe response at 5 and 8 weeks. This study reports the biological responses of four calcium hydroxide compounds used as cavity liners in non-exposures in a series of primary and permanent teeth of monkeys using ZOE and silicate as controls. Responses to the four Ca(OH) 2 compounds were moderate for all the experimental compounds except Pulpdent which was more severe at the early time period tested. ZOE produced a milder and silicate a severe response at all periods. All of these compounds were placed by random selection in anterior and posterior teeth of both arches and five teeth were evaluated in both primary and permanent teeth at 3 days, 5 and 8 weeks.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74743/1/j.1600-0714.1976.tb01759.x.pd