318 research outputs found

    On the Erasure and Regeneration of the Primordial Baryon Asymmetry by Sphalerons

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    We show that a cosmological baryon asymmetry generated at the GUT scale, which would be destroyed at lower temperatures by sphalerons and possible new B- or L-violating effects, can naturally be preserved by an asymmetry in the number of right-handed electrons. This results in a significant softening of previously derived baryogenesis-based constraints on the strength of exotic B- or L-violating interactions.Comment: 10 pp. LaTex (2 figures, included) UMN-TH-1201/9

    Association and interaction analyses of eight genes under asthma linkage peaks

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    Background: Linkage studies have implicated the 2q33, 9p21, 11q13 and 20q13 regions in the regulation of allergic disease. The aim of this study was to test genetic variants in candidate genes from these regions for association with specific asthma traits. Methods: Ninety-five single nucleotide polymorphisms (SNP) located in eight genes (CD28, CTLA4, ICOS, ADAM23, ADAMTSL1, MS4A2, CDH26 and HRH3) were genotyped in >5000 individuals from Australian (n = 1162), Dutch (n = 99) and Danish (n = 303) families. Traits tested included doctor-diagnosed asthma, atopy, airway obstruction, total serum immunoglobulin (Ig) E levels and eosinophilia. Association was tested using both multivariate and univariate methods, with gene-wide thresholds for significance determined through simulation. Gene-by-gene and gene-by-environment analyses were also performed. Results: There was no overall evidence for association with seven of the eight genes tested when considering all genetic variation assayed in each gene. The exception was MS4A2 on chromosome 11q13, which showed weak evidence for association with IgE (gene-wide P < 0.05, rs502581). There were no significant gene-by-gene or gene-by-environment interaction effects after accounting for the number of tests performed. Conclusions: The individual variants genotyped in the 2q33, 9p21 and 20q13 regions do not explain a large fraction of the variation in the quantitative traits tested or have a major impact on asthma or atopy risk. Our results are consistent with a weak effect of MS4A2 polymorphisms on the variation of total IgE levels. © 2009 John Wiley & Sons A/S

    Mapping shallow urban groundwater temperatures, a case study from Cardiff, UK

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    Low-enthalpy ground source heating systems can help to reduce our dependence on fossil fuels, in turn reducing greenhouse gas emissions and increasing energy security. To de-risk and support the sustainable development, regulation and management of ground source heating systems in urban areas, detailed baseline mapping of groundwater temperatures is required. Groundwater temperatures were measured in 168 monitoring boreholes primarily within a Quaternary sand and gravel aquifer in the city of Cardiff, UK. The data have been used to create the first city-wide map of shallow groundwater temperatures in the UK. This map can be used both to support development of ground source heating and to act as a detailed baseline from which to measure change. Shallow groundwater temperatures under the city were found to be 2°C warmer than the UK average groundwater temperature and this additional heat is attributed to the urban heat island. The zone of seasonal fluctuation varies from 7.1 and 15.5 m below ground level (mbgl) within the shallow Quaternary aquifer, averaging 9.5 mbgl. Deeper groundwater temperature profiles incorporating both the Quaternary and bedrock aquifers suggest that a ‘zone of anthropogenic influence’ exists down to about 70 mbgl. Around a third of the UK's greenhouse gas emissions are produced by space heating, and the UK Government recognizes the need to change the way heat is produced and consumed so as to reduce the impacts of climate change and improve energy security (DECC 2013). In response to this driver the UK Government has established targets in the legally binding Climate Change Act 2008 to reduce greenhouse gas emissions by 80% from the 1990 baseline by 2050. In Wales the Well-being of Future Generations (Wales) Act 2015 requires public bodies to take action to undertake sustainable development to drive social, economic and environmental benefits, both now and into the future. Low-enthalpy ground source heating systems, when deployed in a sustainable manner, can provide a low-cost, low-carbon and secure form of heating (e.g. Allen et al. 2003). Ground source heat pumps can broadly be classified as either ‘open-loop’ or ‘closed-loop’ systems. Open-loop systems require the abstraction of groundwater, which is passed through a heat exchanger before being returned to the aquifer. Open-loop systems can have a higher coefficient of performance (COP) and require fewer boreholes where shallow groundwater is available. Open-loop systems may not be suitable if water cannot be successfully recharged to the same aquifer and there are also requirements for abstraction licences and discharge permits or exemptions. The closed-loop system uses a sealed pipe that can be either laid flat or installed vertically into a borehole. These systems often require a greater number of boreholes, increasing cost; however, in the UK they do not require licensing and this can reduce costs. Sustainable development of ground source heat pump (GSHP) systems for both heating and cooling requires characterization of baseline groundwater temperatures. Knowledge of baseline conditions is important to support the design and regulation of GSHP. Baseline temperature data are required to assess the potential impacts of multiple ground source heating and cooling systems so as to avoid interactions between neighbouring systems (Fry 2009; Headon et al. 2009). It is anticipated that if negative interactions between ground source heating and cooling systems continue, some aquifers, mainly in densely populated cities, will need to be managed in terms of heat as well as groundwater resources (Banks et al. 2009). Regulators need legal, policy and scientific tools to support risk-based management of the subsurface, and one such tool is baseline temperature data and mapping of groundwater heat resources. The shallow gravel aquifer in Cardiff is a favourable geological setting in which to develop open-loop ground source heating systems. To support the sustainable development of this technology we have produced the first city-wide baseline map of groundwater temperatures and better defined the depth of the zone of seasonal fluctuation. The data and supporting map outputs will provide an independent source of information for system designers and installers, housing developers, space planners and regulators that is intended to help inform planning decisions and optimize design of GSHP schemes. Additionally, we describe observed seasonal groundwater temperature variation and define the base of the ‘zone of seasonal fluctuation’, which will allow developers to locate abstraction boreholes at depths unaffected by seasonal temperature changes. An initial estimate of available thermal energy that could be transferred from existing dewatering abstractions is made as an illustration of the city-wide potential

    Establishing an urban geo-observatory to support sustainable development of shallow subsurface heat recovery and storage

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    Low-enthalpy ground source heating and cooling is recognised as one strategy that can contribute towards reducing reliance on traditional, increasingly insecure, CO2-intense thermal power generation, as well as helping to address fuel poverty. Development of this technology is applicable in urban areas where high housing density often coincides with the presence of shallow aquifers. In urban areas groundwater temperatures can be elevated due to the subsurface Urban Heat Island effect. Uptake and development of this technology is often limited by initial investment costs, however, baseline temperature monitoring and characterisation of urban aquifers, conducted in partnership with local authorities, can provide a greater degree of certainty around resource and sustainability that can facilitate better planning, regulation and management of subsurface heat. We present a novel high-density, city-scale groundwater temperature observatory and introduce a 3D geological model aimed at addressing the needs of developers, planners, regulators and policy makers. The Cardiff Geo-Observatory measures temperature in a Quaternary aged sand and gravel aquifer in 61 boreholes and at a pilot shallow open-loop ground source heating system. We show that repurposing existing infrastructure can provide a cost effective method of developing monitoring networks, and make recommendations on establishing similar geo-observatories

    Higgs boson mass limits in perturbative unification theories

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    Motivated in part by recent demonstrations that electroweak unification into a simple group may occur at a low scale, we detail the requirements on the Higgs mass if the unification is to be perturbative. We do this for the Standard Model effective theory, minimal supersymmetry, and next-to-minimal supersymmetry with an additional singlet field. Within the Standard Model framework, we find that perturbative unification with sin2(thetaW)=1/4 occurs at Lambda=3.8 TeV and requires mh<460 GeV, whereas perturbative unification with sin2(thetaW)=3/8 requires mh<200 GeV. In supersymmetry, the presentation of the Higgs mass predictions can be significantly simplified, yet remain meaningful, by using a single supersymmetry breaking parameter Delta_S. We present Higgs mass limits in terms of Delta_S for the minimal supersymmetric model and the next-to-minimal supersymmetric model. We show that in next-to-minimal supersymmetry, the Higgs mass upper limit can be as large as 500 GeV even for moderate supersymmetry masses if the perturbative unification scale is low (e.g., Lambda=10 TeV).Comment: 20 pages, latex, 6 figures, references adde

    The status of GEO 600

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    The GEO 600 laser interferometer with 600m armlength is part of a worldwide network of gravitational wave detectors. GEO 600 is unique in having advanced multiple pendulum suspensions with a monolithic last stage and in employing a signal recycled optical design. This paper describes the recent commissioning of the interferometer and its operation in signal recycled mode

    Search for Higgs Bosons in e+e- Collisions at 183 GeV

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    The data collected by the OPAL experiment at sqrts=183 GeV were used to search for Higgs bosons which are predicted by the Standard Model and various extensions, such as general models with two Higgs field doublets and the Minimal Supersymmetric Standard Model (MSSM). The data correspond to an integrated luminosity of approximately 54pb-1. None of the searches for neutral and charged Higgs bosons have revealed an excess of events beyond the expected background. This negative outcome, in combination with similar results from searches at lower energies, leads to new limits for the Higgs boson masses and other model parameters. In particular, the 95% confidence level lower limit for the mass of the Standard Model Higgs boson is 88.3 GeV. Charged Higgs bosons can be excluded for masses up to 59.5 GeV. In the MSSM, mh > 70.5 GeV and mA > 72.0 GeV are obtained for tan{beta}>1, no and maximal scalar top mixing and soft SUSY-breaking masses of 1 TeV. The range 0.8 < tanb < 1.9 is excluded for minimal scalar top mixing and m{top} < 175 GeV. More general scans of the MSSM parameter space are also considered.Comment: 49 pages. LaTeX, including 33 eps figures, submitted to European Physical Journal

    A Measurement of the Product Branching Ratio f(b->Lambda_b).BR(Lambda_b->Lambda X) in Z0 Decays

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    The product branching ratio, f(b->Lambda_b).BR(Lambda_b->Lambda X), where Lambda_b denotes any weakly-decaying b-baryon, has been measured using the OPAL detector at LEP. Lambda_b are selected by the presence of energetic Lambda particles in bottom events tagged by the presence of displaced secondary vertices. A fit to the momenta of the Lambda particles separates signal from B meson and fragmentation backgrounds. The measured product branching ratio is f(b->Lambda_b).BR(Lambda_b->Lambda X) = (2.67+-0.38(stat)+0.67-0.60(sys))% Combined with a previous OPAL measurement, one obtains f(b->Lambda_b).BR(Lambda_b->Lambda X) = (3.50+-0.32(stat)+-0.35(sys))%.Comment: 16 pages, LaTeX, 3 eps figs included, submitted to the European Physical Journal

    Measurement of the Michel Parameters in Leptonic Tau Decays

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    The Michel parameters of the leptonic tau decays are measured using the OPAL detector at LEP. The Michel parameters are extracted from the energy spectra of the charged decay leptons and from their energy-energy correlations. A new method involving a global likelihood fit of Monte Carlo generated events with complete detector simulation and background treatment has been applied to the data recorded at center-of-mass energies close to sqrt(s) = M(Z) corresponding to an integrated luminosity of 155 pb-1 during the years 1990 to 1995. If e-mu universality is assumed and inferring the tau polarization from neutral current data, the measured Michel parameters are extracted. Limits on non-standard coupling constants and on the masses of new gauge bosons are obtained. The results are in agreement with the V-A prediction of the Standard Model.Comment: 32 pages, LaTeX, 9 eps figures included, submitted to the European Physical Journal

    Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo

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    Major depressive disorder (MDD) is a common complex trait with enormous public health significance. As part of the Genetic Association Information Network initiative of the US Foundation for the National Institutes of Health, we conducted a genome-wide association study of 435 291 single nucleotide polymorphisms (SNPs) genotyped in 1738 MDD cases and 1802 controls selected to be at low liability for MDD. Of the top 200, 11 signals localized to a 167 kb region overlapping the gene piccolo (PCLO, whose protein product localizes to the cytomatrix of the presynaptic active zone and is important in monoaminergic neurotransmission in the brain) with P-values of 7.7 × 1
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