Phenolic Glycosides from the Twigs of <i>Salix glandulosa</i>

As a part of an ongoing search for bioactive constituents from Korean medicinal plants, the phytochemical investigations of the twigs of <i>Salix glandulosa</i> afforded 12 new phenolic glycosides (<b>1</b>–<b>12</b>) and a known analogue (<b>13</b>). The structures of <b>1</b>–<b>13</b> were characterized by a combination of NMR methods (¹H and ¹³C NMR, ¹H–¹H COSY, HMQC, and HMBC), chemical hydrolysis, and GC/MS. The absolute configuration of <b>13</b> [(1<i>R</i>,2<i>S</i>)-2-hydroxycyclohexyl-2′-<i>O</i>-<i>trans</i>-<i>p</i>-coumaroyl-β-d-glucopyranoside] was determined for the first time. Compounds <b>1</b>–<b>3</b>, <b>6</b>, and <b>7</b> exhibited inhibitory effects on nitric oxide production in lipopolysaccharide-activated murine microglial cells (IC₅₀ values in the range 6.6–20.5 μM)

High-Performing Thin-Film Transistors in Large Spherulites of Conjugated Polymer Formed by Epitaxial Growth on Removable Organic Crystalline Templates

Diketopyrrolopyrrole (DPP)-based conjugated polymer <b>PDTDPPQT</b> was synthesized and was used to perform epitaxial polymer crystal growth on removable 1,3,5-trichlorobenzene crystallite templates. A thin-film transistor (TFT) was successfully fabricated in well-grown large spherulites of <b>PDTDPPQT</b>. The charge carrier mobility along the radial direction of the spherulites was measured to be 5.46–12.04 cm² V^–1 s^–1, which is significantly higher than that in the direction perpendicular to the radial direction. The dynamic response of charge transport was also investigated by applying a pulsed bias to TFTs loaded with a resistor (∼20 MΩ). The charge-transport behaviors along the radial direction and perpendicular to the radial direction were investigated by static and dynamic experiments through a resistor-loaded (RL) inverter. The RL inverter made of <b>PDTDPPQT</b>-based TFT operates well, maintaining a fairly high switching voltage ratio (<i>V</i>_out^ON/<i>V</i>_out^OFF) at a relatively high frequency when the source-drain electrodes are aligned parallel to the radial direction