396 research outputs found
Aggressive Encounters & White Fragility: Deconstructing the Trope of the Angry Black Woman
Black women in the United States are the frequent targets of bias-filled interactions in which aggressors: (1) denigrate Black women; and (2) blame those women who elect to challenge the aggressor’s acts and the bias that fuels them. This Article seeks to raise awareness of these “aggressive encounters” and to challenge a prevailing narrative about Black women and anger. It examines the myriad circumstances (both professional and social) in which aggressive encounters occur and the ways in which these encounters expose gender and racial hierarchies. It then explores how the intersectional nature of Black women’s identities triggers a particularized stereotype or trope of the “Angry Black Woman” and explains how this trope is often invoked in aggressive encounters to deflect attention from the aggressor and to project blame onto the target. After discussing the harmful effects of aggressive encounters and the absence of effective legal mechanisms to address them, the Article sets forth tangible steps that individuals can take to minimize their incidence
Does Being Greek Work?: An Analysis of the Effect of Greek Affiliation on Grade Point Average and Retention
The purpose of this study was to investigate if affiliated students are more academically successful and better retained compared to their nonaffiliated counterparts. Utilizing data given to me by the Committee on Retention Efforts (CORE), I found that affiliated students were more academically successfully and better retained than their nonaffiliated counterparts. Additionally, I found that affiliated women were more academically successful and better retained than their affiliated male and nonaffiliated counterparts. The title of my thesis is Does Being Greek Work?, and my findings indicate that being Greek does in fact work
Does Being Greek Work?: An Analysis of the Effect of Greek Affiliation on Grade Point Average and Retention
The purpose of this study was to investigate if affiliated students are more academically successful and better retained compared to their nonaffiliated counterparts. Utilizing data given to me by the Committee on Retention Efforts (CORE), I found that affiliated students were more academically successfully and better retained than their nonaffiliated counterparts. Additionally, I found that affiliated women were more academically successful and better retained than their affiliated male and nonaffiliated counterparts. The title of my thesis is Does Being Greek Work?, and my findings indicate that being Greek does in fact work
Contested cultures of care: research with and for the plus one community on the plus one experience - evaluation report
Derbyshire and Nottinghamshire Collaborative Outreach Projec
Reconciling care and justice in contesting social harm through performance and arts practice with looked after children and care leavers
The proportion of young people taken into the care of the state has increased recently and there is evidence that this social group suffer negative long-term outcomes that might be conceptualised by the emergent criminological category of ‘social harm’. This discussion is then related to debates on social work which have juxtaposed an ethics of care and justice. This paper reports findings from an innovative arts-based intervention with Looked After Children and Young People and concludes that holding these competing value sets in creative tension is central to the success of the programme in helping young people to cope with and contest social harm
GWAS study of color and texture on natto soybeans
Soybeans are an essential component to the contemporary Japanese diet. Natto is a Japanese dish made by fermenting soybeans, and the physical properties of the unprocessed soybeans will affect the natto produced. Pale yellow soybeans that are slightly firm in texture are preferred. The genetic improvement of these qualities is achieved through breeding. A genome-wide association study (GWAS) is an important tool for soybean breeding and can be used to associate genomes with a certain genotype. Color and texture are the selected phenotypes in this study and a GWAS program was ran to associate the genotype markers with the phenotypes. None of the markers in the study reached the threshold of significance and therefore are not considered to be associated with one of the phenotypes. Further research is necessary.Oklahoma Louis Stokes Alliance for Minority Participation ProgramNational Science Foundation (U.S.). Research Experience for UndergraduatesCrop, Soil and Environmental Science
Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R
This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Material from this article can be used in other publications provided that the correct acknowledgement is given with the reproduced material.The interaction of IGF-II with the insulin receptor (IR) and type 1 insulin-like growth factor receptor (IGF-1R) has recently been identified as potential therapeutic target for the treatment of cancer. Understanding the interactions of IGF-II with these receptors is required for the development of potential anticancer therapeutics. This work describes an efficient convergent synthesis of native IGF-II and two nonnative IGF-II analogues with coumarin fluorescent probes incorporated at residues 19 and 28. These fluorescent analogues bind with nanomolar affinities to the IGF-1R and are suitable for use in fluorescence resonance energy transfer (FRET) studies. From these studies the F19Cou IGF-II and F28Cou IGF-II proteins were identified as good probes for investigating the binding interactions of IGF-II with the IGF-1R and its other high affinity binding partners
High Nasopharyngeal Carriage of Non-Vaccine Serotypes in Western Australian Aboriginal People Following 10 Years of Pneumococcal Conjugate Vaccination
BackgroundInvasive pneumococcal disease (IPD) continues to occur at high rates among Australian Aboriginal people. The seven-valent pneumococcal conjugate vaccine (7vPCV) was given in a 2-4-6-month schedule from 2001, with a 23-valent pneumococcal polysaccharide vaccine (23vPPV) booster at 18 months, and replaced with 13vPCV in July 2011. Since carriage surveillance can supplement IPD surveillance, we have monitored pneumococcal carriage in western Australia (WA) since 2008 to assess the impact of the 10-year 7vPCV program. MethodsWe collected 1,500 nasopharyngeal specimens from Aboriginal people living in varied regions of WA from August 2008 until June 2011. Specimens were cultured on selective media. Pneumococcal isolates were serotyped by the quellung reaction. ResultsStreptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis were carried by 71.9%, 63.2% and 63.3% respectively of children <5 years of age, and 34.6%, 22.4% and 27.2% of people ≥5 years. Of 43 pneumococcal serotypes identified, the most common were 19A, 16F and 6C in children <5 years, and 15B, 34 and 22F in older people. 7vPCV serotypes accounted for 14.5% of all serotypeable isolates, 13vPCV for 32.4% and 23vPPV for 49.9%, with little variation across all age groups. Serotypes 1 and 12F were rarely identified, despite causing recent IPD outbreaks in WA. Complete penicillin resistance (MIC ≥2µg/ml) was found in 1.6% of serotype 19A (5.2%), 19F (4.9%) and 16F (3.2%) isolates and reduced penicillin susceptibility (MIC ≥0.125µg/ml) in 24.9% of isolates, particularly 19F (92.7%), 19A (41.3%), 16F (29.0%). Multi-resistance to cotrimoxazole, tetracycline and erythromycin was found in 83.0% of 23F isolates. Among non-serotypeable isolates 76.0% had reduced susceptibility and 4.0% showed complete resistance to penicillin.ConclusionsTen years after introduction of 7vPCV for Aboriginal Australian children, 7vPCV serotypes account for a small proportion of carried pneumococci. A large proportion of circulating serotypes are not covered by any currently licensed vaccine
The cost of providing care by family and friends (informal care) in the last year of life: A population observational study
Introduction: Little is known about replacement costs of care provided by informal carers during the last year of life for people dying of cancer and non-cancer diseases. Aim: To estimate informal caregiving costs and explore the relationship with carer and decedent characteristics. Design: National observational study of bereaved carers. Questions included informal end-of-life caregiving into the 2017 Health Survey for England including estimated recalled frequency, duration and intensity of care provision. We estimated replacement costs for a decedent’s last year of life valuing time at the price of a substitutable activity. Spearman rank correlations and multivariable linear regression were used to explore relationships with last year of life costs. Setting/participants: Adult national survey respondents – England. Results: A total of 7997 adults were interviewed from 5767/9612 (60%) of invited households. Estimated replacement costs of personal care and other help were £27,072 and £13,697 per carer and a national cost of £13.2 billion and £15.5 billion respectively. Longer care duration and intensity, older age, death at home (lived together), non-cancer cause of death and greater deprivation were associated with increased costs. Female sex, and not accessing ‘other care services’ were related to higher costs for other help only. Conclusion: We provide a first adult general population estimate for replacement informal care costs in the last year of life of £41,000 per carer per decedent and highlight characteristics associated with greater costs. This presents a major challenge for future universal care coverage as the pool of people providing informal care diminish with an ageing population
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