659 research outputs found
Self-adaptation and viscous selection in concentrated two-dimensional vortex dipoles
International audienceIn this Letter we deal with 2D direct numerical simulations of concentrated vortex dipoles. We show that various initial dipolar vorticity distributions evolve towards a specific family of dipoles parametrized by the dipole aspect ratio a/b, where a is the radius of the vortices based on the vorticity polar moment in half a plane and b is the separation between the vortex centroids. This convergence is achieved through viscous effects. The considered Reynolds numbers Re= G/v are Re= 3000 and Re= 15000. Moreover, all the dipoles of this family are quasi-steady solutions of the Euler equations. Their scatter plots and drift velocities are given for a/b<03. © 2000 American Institute of Physics
Spatio-temporal development of the long and short-wave vortex-pair instabilities
International audienceWe consider the spatio-temporal development of the long-wave and short-wave instabilities in a pair of counter-rotating vortices in the presence of a uniform axial advection velocity. The stability properties depend upon the aspect ratio a/b of the vortex pair, where a is the core radius of the vortices and b their separation, and upon W0/U0 the ratio between the self-induced velocity of the pair and the axial advection velocity. For sufficiently small W0/U0, the instabilities are convective, but an increase of W0/U0 may lead to an absolute instability. Near the absolute instability threshold, spatial growth rates are larger than those predicted by temporal stability theory. Considering aeronautical applications, it is shown that instabilities of the type considered in this communication cannot become absolute in farfield wakes of high aspect ratio wings. © 2000 American Institute of Physics
Can the jamming transition be described using equilibrium statistical mechanics?
When materials such as foams or emulsions are compressed, they display solid
behaviour above the so-called `jamming' transition. Because compression is done
out-of-equilibrium in the absence of thermal fluctuations, jamming appears as a
new kind of a nonequilibrium phase transition. In this proceeding paper, we
suggest that tools from equilibrium statistical mechanics can in fact be used
to describe many specific features of the jamming transition. Our strategy is
to introduce thermal fluctuations and use statistical mechanics to describe the
complex phase behaviour of systems of soft repulsive particles, before sending
temperature to zero at the end of the calculation. We show that currently
available implementations of standard tools such as integral equations,
mode-coupling theory, or replica calculations all break down at low temperature
and large density, but we suggest that new analytical schemes can be developed
to provide a fully microscopic, quantitative description of the jamming
transition.Comment: 8 pages, 6 figs. Talk presented at Statphys24 (July 2010, Cairns,
Australia
Inducible Control of Subcellular RNA Localization Using a Synthetic Protein-RNA Aptamer Interaction
Evidence is accumulating in support of the functional importance of subcellular RNA localization in diverse biological contexts. In different cell types, distinct RNA localization patterns are frequently observed, and the available data indicate that this is achieved through a series of highly coordinated events. Classically, cis–elements within the RNA to be localized are recognized by RNA-binding proteins (RBPs), which then direct specific localization of a target RNA. Until now, the precise control of the spatiotemporal parameters inherent to regulating RNA localization has not been experimentally possible. Here, we demonstrate the development and use of a chemically–inducible RNA–protein interaction to regulate subcellular RNA localization. Our system is composed primarily of two parts: (i) the Tet Repressor protein (TetR) genetically fused to proteins natively involved in localizing endogenous transcripts; and (ii) a target transcript containing genetically encoded TetR–binding RNA aptamers. TetR–fusion protein binding to the target RNA and subsequent localization of the latter are directly regulated by doxycycline. Using this platform, we demonstrate that enhanced and controlled subcellular localization of engineered transcripts are achievable. We also analyze rules for forward engineering this RNA localization system in an effort to facilitate its straightforward application to studying RNA localization more generally.National Institutes of Health (U.S.) (Director’s New Innovator Award Program (grant number 1DP2OD007124 )
Amplifier and resonator dynamics of a low-Reynolds-number recirculation bubble in a global framework
International audienceThe stability behaviour of a low-Reynolds-number recirculation flow developing in a curved channel is investigated using a global formulation of hydrodynamic stability theory. Both the resonator and amplifier dynamics are investigated. The resonator dynamics, which results from the ability of the flow to self-sustain perturbations, is studied through a modal stability analysis. In agreement with the literature, the flow becomes globally unstable via a three-dimensional stationary mode. The amplifier dynamics, which is characterized by the ability of the flow to exhibit large transient amplifications of initial perturbations, is studied by looking for the two- and three-dimensional initial perturbations that maximize the energy gain over a given time horizon. The optimal initial two-dimensional perturbations have the form of wave packets localized in the upstream part of the recirculation bubble. It is shown that they are first amplified while travelling downstream along the shear layer of the recirculation bubble and then decay when leaving the recirculation bubble. Maximal energy gain is thus achieved for a time horizon approximately corresponding to the propagation of the wave packet along the whole recirculation bubble. The resonator and amplifier dynamics are associated with different types of structures in the flow: three-dimensional steady structures for the resonator dynamics and nearly two-dimensional unsteady structures for the amplifier dynamics. A comparison of the strength of the two dynamics is proposed. The transient energetic growth of the two-dimensional unsteady perturbations is large at moderate time, compared to the very weak exponential growth of the three-dimensional stationary mode. This suggests that, as soon as there is noise in the system, the amplifier dynamics dominates the resonator dynamics, thus explaining the appearance of unsteadiness rather than the emergence of stationary structures in similar experimental flows. © 2008 Cambridge University Press
Analyse 3d de la marche en pratique clinique après ligamentoplastie du genou par DIDT : utilisation du système KNEE KG
Direct and adjoint global modes of a recirculation bubble: Lift-up and convective non-normalities
International audienceThe stability of the recirculation bubble behind a smoothed backward-facing step is numerically computed. Destabilization occurs first through a stationary three-dimensional mode. Analysis of the direct global mode shows that the instability corresponds to a deformation of the recirculation bubble in which streamwise vortices induce low- and high-speed streaks as in the classical lift-up mechanism. Formulation of the adjoint problem and computation of the adjoint global mode show that both the lift-up mechanism associated with the transport of the base flow by the perturbation and the convective non-normality associated with the transport of the perturbation by the base flow explain the properties of the flow. The lift-up non-normality differentiates the direct and adjoint modes by their component: the direct is dominated by the streamwise component and the adjoint by the cross-stream component. The convective non-normality results in a different localization of the direct and adjoint global modes, respectively downstream and upstream. The implications of these properties for the control problem are considered. Passive control, to be most efficient, should modify the flow inside the recirculation bubble where direct and adjoint global modes overlap, whereas active control, by for example blowing and suction at the wall, should be placed just upstream of the separation point where the pressure of the adjoint global mode is maximum. © 2009 Cambridge University Press
Anisotropy in Homogeneous Rotating Turbulence
The effective stress tensor of a homogeneous turbulent rotating fluid is
anisotropic. This leads us to consider the most general axisymmetric four-rank
``viscosity tensor'' for a Newtonian fluid and the new terms in the turbulent
effective force on large scales that arise from it, in addition to the
microscopic viscous force. Some of these terms involve couplings to vorticity
and others are angular momentum non conserving (in the rotating frame).
Furthermore, we explore the constraints on the response function and the
two-point velocity correlation due to axisymmetry. Finally, we compare our
viscosity tensor with other four-rank tensors defined in current approaches to
non-rotating anisotropic turbulence.Comment: 14 pages, RevTe
A statistical approach for predicting grassland degradation in disturbance-driven landscapes
Maintaining a land base that supports safe and realistic training operations is a significant challenge for military land managers which can be informed by frequent monitoring of land condition in relation to management practices. This study explores the relationship between fire and trends in tallgrass prairie vegetation at military and non -military sites in the Kansas Flint Hills. The response variable was the longterm linear trend (2001-2010) of surface greenness measured by MODIS NDVI using BFAST time series trend analysis. Explanatory variables included fire regime (frequency and seasonality) and spatial strata based on existing management unit boundaries. Several non-spatial generalized linear models (GLM) were computed to explain trends by fire regime and/or stratification. Spatialized versions of the GLMs were also constructed. For non-spatial models at the military site, fire regime explained little (4%) of the observed surface greenness trend compared to strata alone (7% - 26%). The non-spatial and spatial models for the non -military site performed better for each explanatory variable and combination tested with fire regime. Existing stratifications contained much of the spatial structure in model residuals. Fire had only a marginal effect on surface greenness trends at the military site despite the use of burning as a grassland management tool. Interestingly, fire explained more of the trend at the nonmilitary site and models including strata improved explanatory power. Analysis of spatial model predictors based on management unit stratification suggested ways to reduce the number of strata while achieving similar performance and may benefit managers of other public areas lacking sound data regarding land usage
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