53 research outputs found
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Climate Change Science Compendium 2009
This document was compiled as an annual snapshot of peer-reviewed research about climate change
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Climate Change: Science Compendium 2009
This Climate Change Science Compendium, based on the wealth of peer-reviewed research published by researchers and institutions since 2006, has been compiled by UNEP in response to that request. The findings indicate that ever more rapid environmental change is underway with the pace and the scale of climate change accelerating, along with the confidence among researchers in their forecasts. The Compendium will provide important insights into the rapidly developing and fast moving realm of climate science so that the choices made by leaders in Copenhagen in December are informed by the best and the latest research available to the international community
Integrating Voice-Based Machine Learning Technology into Complex Home Environments
To demonstrate the value of machine learning based smart health technologies,
researchers have to deploy their solutions into complex real-world environments
with real participants. This gives rise to many, oftentimes unexpected,
challenges for creating technology in a lab environment that will work when
deployed in real home environments. In other words, like more mature
disciplines, we need solutions for what can be done at development time to
increase success at deployment time. To illustrate an approach and solutions,
we use an example of an ongoing project that is a pipeline of voice based
machine learning solutions that detects the anger and verbal conflicts of the
participants. For anonymity, we call it the XYZ system. XYZ is a smart health
technology because by notifying the participants of their anger, it encourages
the participants to better manage their emotions. This is important because
being able to recognize one's emotions is the first step to better managing
one's anger. XYZ was deployed in 6 homes for 4 months each and monitors the
emotion of the caregiver of a dementia patient. In this paper we demonstrate
some of the necessary steps to be accomplished during the development stage to
increase deployment time success, and show where continued work is still
necessary. Note that the complex environments arise both from the physical
world and from complex human behavior
RobotPerf: An Open-Source, Vendor-Agnostic, Benchmarking Suite for Evaluating Robotics Computing System Performance
We introduce RobotPerf, a vendor-agnostic benchmarking suite designed to
evaluate robotics computing performance across a diverse range of hardware
platforms using ROS 2 as its common baseline. The suite encompasses ROS 2
packages covering the full robotics pipeline and integrates two distinct
benchmarking approaches: black-box testing, which measures performance by
eliminating upper layers and replacing them with a test application, and
grey-box testing, an application-specific measure that observes internal system
states with minimal interference. Our benchmarking framework provides
ready-to-use tools and is easily adaptable for the assessment of custom ROS 2
computational graphs. Drawing from the knowledge of leading robot architects
and system architecture experts, RobotPerf establishes a standardized approach
to robotics benchmarking. As an open-source initiative, RobotPerf remains
committed to evolving with community input to advance the future of
hardware-accelerated robotics
Seminal Plasma Enhances Cervical Adenocarcinoma Cell Proliferation and Tumour Growth In Vivo
Cervical cancer is one of the leading causes of cancer-related death in women in sub-Saharan Africa. Extensive evidence has shown that cervical cancer and its precursor lesions are caused by Human papillomavirus (HPV) infection. Although the vast majority of HPV infections are naturally resolved, failure to eradicate infected cells has been shown to promote viral persistence and tumorigenesis. Furthermore, following neoplastic transformation, exposure of cervical epithelial cells to inflammatory mediators either directly or via the systemic circulation may enhance progression of the disease. It is well recognised that seminal plasma contains an abundance of inflammatory mediators, which are identified as regulators of tumour growth. Here we investigated the role of seminal plasma in regulating neoplastic cervical epithelial cell growth and tumorigenesis. Using HeLa cervical adenocarcinoma cells, we found that seminal plasma (SP) induced the expression of the inflammatory enzymes, prostaglandin endoperoxide synthase (PTGS1 and PTGS2), cytokines interleukin (IL) -6, and -11 and vascular endothelial growth factor-A(VEGF-A). To investigate the role of SP on tumour cell growth in vivo, we xenografted HeLa cells subcutaneously into the dorsal flank of nude mice. Intra-peritoneal administration of SP rapidly and significantly enhanced the tumour growth rate and size of HeLa cell xenografts in nude mice. As observed in vitro, we found that SP induced expression of inflammatory PTGS enzymes, cytokines and VEGF-A in vivo. Furthermore we found that SP enhances blood vessel size in HeLa cell xenografts. Finally we show that SP-induced cytokine production, VEGF-A expression and cell proliferation are mediated via the induction of the inflammatory PTGS pathway
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Advancing a toolkit of diverse futures approaches for global environmental assessments
Global Environmental Assessments (GEAs) are in a unique position to influence environmental decision-making in the context of sustainability challenges. To do this effectively, however, new methods are needed to respond to the needs of decision-makers for a more integrated, contextualized and goal-seeking evaluation of different policies, geared for action from global to local. While scenarios are an important tool for GEAs to link short-term decisions and medium and long-term consequences, these current information needs cannot be met only through deductive approaches focused on the global level. In this paper, we argue that a more diverse set of futures tools operating at multiple scales are needed to improve GEA scenario development and analysis to meet the information needs of policymakers and other stakeholders better. Based on the literature, we highlight four challenges that GEAs need to be able to address in order to contribute to global environmental decision-making about the future: 1. anticipate unpredictable future conditions; 2. be relevant at multiple scales, 3. include diverse actors, perspectives and contexts; and 4. leverage the imagination to inspire action. We present a toolbox of future-oriented approaches and methods that can be used to effectively address the four challenges currently faced by GEAs
Labile Carbon and Other Soil Quality Indicators in Two Tillage Systems during Transition to Organic Agriculture
Weed management is one of the primary challenges for producers transitioning from conventional to organic agriculture. Tillage and the use of cover crops are two weed control tactics available to farmers transitioning to organic management, but little is known about their interactive effects on soil quality during the transition period. We investigated the response of soils to tillage and initial cover crop during the 3-year transition to organic in a cover crop-soybean (Glycine max)-maize (Zea mays) rotation in the Mid-Atlantic region of the USA. The tillage treatment contrasted full, inversion tillage with moldboard plowing (FT) versus reduced tillage with chisel plowing (RT). The cover crop treatment contrasted annual versus mostly perennial species during the first year of the rotation. The experiment was initiated twice (Start 1 and Start 2), in consecutive years in adjacent fields. By the end of the experiment, labile carbon, electrical conductivity, pH and soil moisture were all greater under RT than under FT in both starts. Soil organic matter and several other soil attributes were greater under RT than under FT in Start 1, but not in Start 2, perhaps owing to differences between starts in initial field conditions and realized weather. Soil attributes did not differ between the two cover crop treatments. Combining our soils results with agronomic and economic analyses on these plots suggests that using RT during the organic transition can increase soil quality without compromising yield and profitability
The development of the PARENTS: a tool for parents to assess residents’ non-technical skills in pediatric emergency departments
Abstract Background Parents can assess residents’ non-technical skills (NTS) in pediatric emergency departments (EDs). There are no assessment tools, with validity evidence, for parental use in pediatric EDs. The purpose of this study was to develop the Parents’ Assessment of Residents Enacting Non-Technical Skills (PARENTS) educational assessment tool and collect three sources of validity evidence (i.e., content, response process, internal structure) for it. Methods We established content evidence for the PARENTS through interviews with physician-educators and residents, focus groups with parents, a literature review, and a modified nominal group technique with experts. We collected response process evidence through cognitive interviews with parents. To examine the internal structure evidence, we administered the PARENTS and performed exploratory factor analysis. Results Initially, a 20-item PARENTS was developed. Cognitive interviews led to the removal of one closed-ended item, the addition of resident photographs, and wording/formatting changes. Thirty-seven residents and 434 parents participated in the administration of the resulting 19-item PARENTS. Following factor analysis, a one-factor model prevailed. Conclusions The study presents initial validity evidence for the PARENTS. It also highlights strategies for potentially: (a) involving parents in the assessment of residents, (b) improving the assessment of NTS in pediatric EDs, and (c) capturing parents’ perspectives to improve the preparation of future physicians
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