14 research outputs found
Iron Behaving Badly: Inappropriate Iron Chelation as a Major Contributor to the Aetiology of Vascular and Other Progressive Inflammatory and Degenerative Diseases
- Author
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- The Long-Term Intervention with Pravastatin in Ischaemic Disease (LIPID) Study Group
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- Publication venue
- Publication date
- 09/08/2008
- Field of study
The production of peroxide and superoxide is an inevitable consequence of
aerobic metabolism, and while these particular "reactive oxygen species" (ROSs)
can exhibit a number of biological effects, they are not of themselves
excessively reactive and thus they are not especially damaging at physiological
concentrations. However, their reactions with poorly liganded iron species can
lead to the catalytic production of the very reactive and dangerous hydroxyl
radical, which is exceptionally damaging, and a major cause of chronic
inflammation. We review the considerable and wide-ranging evidence for the
involvement of this combination of (su)peroxide and poorly liganded iron in a
large number of physiological and indeed pathological processes and
inflammatory disorders, especially those involving the progressive degradation
of cellular and organismal performance. These diseases share a great many
similarities and thus might be considered to have a common cause (i.e.
iron-catalysed free radical and especially hydroxyl radical generation). The
studies reviewed include those focused on a series of cardiovascular, metabolic
and neurological diseases, where iron can be found at the sites of plaques and
lesions, as well as studies showing the significance of iron to aging and
longevity. The effective chelation of iron by natural or synthetic ligands is
thus of major physiological (and potentially therapeutic) importance. As
systems properties, we need to recognise that physiological observables have
multiple molecular causes, and studying them in isolation leads to inconsistent
patterns of apparent causality when it is the simultaneous combination of
multiple factors that is responsible. This explains, for instance, the
decidedly mixed effects of antioxidants that have been observed, etc...Comment: 159 pages, including 9 Figs and 2184 reference
The associations of perceived neighborhood disorder and physical activity with obesity among African American adolescents
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- A Carver
- A Nilsson
- AD Keita
- AD Keita
- AE Mark
- Akilah Dulin-Keita
- AM Burdette
- AS Richardson
- AT Weston
- BE Molnar
- CC Voorhees
- CE Ross
- CL Ogden
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- HA Raynor
- Herpreet Kaur Thind
- HG Lawman
- HL Burdette
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- JE Gomez
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- KJ Preacher
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- KR Evenson
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- L Franzini
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- LM Powell
- LV Moore
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- MC Nelson
- MH Shishehbor
- Monica L Baskin
- MP Galvez
- NI Larson
- Olivia Affuso
- P Gordon-Larsen
- P Veugelers
- R Ewing
- RA Zwaan
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- RR Pate
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- S Adkins
- SG Trost
- SJ Slater
- SL Handy
- SM Dovey
- SY Kimm
- T Rahman
- TJ Cole
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Time with friends and physical activity as mechanisms linking obesity and television viewing among youth
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- A PĂ©rez
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- AC Huston
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- AF Roche
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- EA Vandewater
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- Elizabeth A Vandewater
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Family health climate scale (FHC-scale): development and validation
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- A Lohaus
- Alexander Woll
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- C Gauze
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- Christina Niermann
- CP Boyd
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- CS Anderson
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- Fabian Krapf
- FF Chen
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- G Ekvall
- HC Kraemer
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- HT Reis
- I Ferreira
- I Ornelas
- J Pugliese
- JA Fredricks
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- JM Berge
- JP Moreno
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- KM Ribisl
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- LA Kurdek
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- M Golan
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- MD Resnick
- MG Patterson
- Miriam Reiner
- MJ Cox
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- MR DiMatteo
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The role of nuclear technologies in the diagnosis and control of livestock diseasesâa review
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- A Loukas
- A MĂŒllbacher
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- Antony G. Luckins
- AP Nordena
- AP Phillips
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- AR Bahaman
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- BD Millar
- C Gauci
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- CA Schuntner
- CC Voigt
- CE Yunker
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- CM Monahan
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- D Levieux
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- DO Odongo
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- EH Barnes
- EH Venter
- EJ Patzer
- EM Moeller
- ER James
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- F Motamedi-Sedeh
- FR Rurangirwa
- G Giuolo Di
- G Spira
- GB Cleland
- GE PĂ©rez
- Gerrit J. Viljoen
- GH Palmer
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- GJ Viljoen
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- GP Dillon
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- H Agadira
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- IE Aradaib
- IG Wright
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- J Creaney
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- J Hayes
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- JA House
- JA MacAskill
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- JM Haresnape
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- JP Bishop
- JR Crowther
- JR Georgi
- JT Paweska
- JT Paweska
- JY Takekawa
- K Amemiya
- KA Hobson
- KA Hobson
- KA Hobson
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- KD Reed
- KJH Robson
- KM Esser
- L Rodak
- LA Dauphin
- LP Kahl
- LW Anderson
- M Alsharifi
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- M Dietrich
- MC Jenkins
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- MG Taylor
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- MJP Lawman
- MP Reichel
- MW Lightowlers
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- NE Collins
- NJ Campbell
- NO Christensen
- P Loi
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- P Nansen
- P Stapp
- PB Cabrera
- PR Boag
- QD Bickle
- R Aboytes-Torres
- R Aloni-Grinstein
- R Bishop
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- R Kaplan
- R Swanepoel
- RA Dalloul
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- RB Williams
- RC Wardley
- RE Duxbury
- RE Purnell
- RE Purnell
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- RG McFarlane
- RJ Chappel
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- RT Fujiwara
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- S Ramamoorthy
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- WC Brown
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- WFH Jarrett
- WI Morrison
- WI Morrison
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- 'Springer Science and Business Media LLC'
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- Field of study
Title: efficacy of a food parenting intervention for mothers with low income to reduce preschoolerâs solid fat and added sugar intakes: a randomized controlled trial
- Author
- Adam Davey
- AE Vaughn
- AF Subar
- Alexandria Kachurak
- AN Herman
- Anna Martin
- AZ Yee
- CD Rehm
- Chantelle N. Hart
- D Feskanich
- D Haire-Joshu
- DC Castro
- DR Keast
- Elena L. Serrano
- ES Powell
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- Gary D. Foster
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- H Skouteris
- Hannah G. Lawman
- Heather M. Polonsky
- HG Lawman
- J Reedy
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- JO Fisher
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- K Malhotra
- Karen J. Ruth
- KI DiSantis
- L Monasta
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- Lisa Harnack
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- MD Hingle
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- SE Barlow
- SF Schakel
- SJ Tucker
- T Ash
- TA Nicklas
- TA Willis
- TG Lohman
- TN Robinson
- YA Sievert
- Yasmeen P. Bruton
- YC Wang
- Z Cui
- Z Yin
- Publication venue
- 'Springer Science and Business Media LLC'
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- Field of study
Parental Perception of Child Bodyweight and Health Among Mexican-American Children with Acanthosis Nigricans
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- A Chiolero
- AE Baughcum
- Athena Ramos
- C Abraham
- C Mendelson
- CA Stuart
- CH Browner
- CL Ogden
- CL Ward
- Dejun Su
- Drissa Toure
- FB Leclere
- GK Singh
- HG Lawman
- Hongmei Wang
- JB Kirby
- JP Elder
- KC Eckstein
- KE Rhee
- L Killion
- LL Birch
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- MA Alexander
- MS Kramer
- N Cossrow
- PB Crawford
- Renaisa Anthony
- RM Andersen
- RS Garcia
- S Caprio
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- S Myers
- SE Barlow
- SS Rich
- T Guran
- T Peak
- Terry T.-K. Huang
- WG Smith
- Y Wang
- Publication venue
- 'Springer Science and Business Media LLC'
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- Field of study
Nondestructive Material Testing Using OCT
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- A Dubois
- A Nemeth
- A Rodriguez
- A Szkulmowska
- B Heise
- B Heise
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- C Fan
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- GM Guss
- GS Kino
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- IB Couceiro
- IS Chronakis
- IV Meglinski
- J Choi
- J Czajkowski
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- J Jasapara
- J Kunicki-Goldfinger
- J Reyes-Esqueda
- J Schwider
- J Veilleux
- JC Clements
- JG Sun
- JL Johnson
- JM Schmitt
- JMA Mauritz
- JP Dunkers
- JP Dunkers
- JP Dunkers
- JP Dunkers
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- K Wiesauer
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- K Wiesauer
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- MM Amaral
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- NH Cho
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2015
- Field of study
Low muscle quality in Japanese type 2 diabetic patients with visceral fat accumulation
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- A Hirata
- AJ Cruz-Jentoft
- AJ Cruz-Jentoft
- Akihito Otsuka
- AM Abbatecola
- AP Rossi
- B Falck
- CA Celis-Morales
- CK Jablecki
- CM Kusminski
- D Yoshida
- DP Leong
- DR Taaffe
- E Han
- ER Mohler 3rd
- Examination Committee of Criteria for âObesity Diseaseâ in Japan
- H Andersen
- H Yamanaka
- HG Lawman
- Hidetoshi Tada
- Hirofumi Nagao
- Hitoshi Nishizawa
- Iichiro Shimomura
- Japanese Society of Nephrology
- JC Chan
- JE Shaw
- JP Després
- Jun Murai
- K Matsuda
- KH Yoon
- KI Tanaka
- LK Chen
- M Leenders
- M Malavolti
- M Ryo
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- Masahide Suzuki
- Mayumi Doi
- N Katakami
- N Maeda
- N Yoshimura
- Norikazu Maeda
- R Bouchi
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- R Huxley
- S Ali
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- S Tuzun
- Shinji Yokota
- Shiro Fukuda
- Shunbun Kita
- SW Park
- SW Park
- SW Park
- T Wang
- Tadashi Nakamura
- Tohru Funahashi
- VP Anbalagan
- World Health Organization
- WR Hiatt
- Y Arita
- Y Matsuzawa
- Y Obata
- Y Okauchi
- Yasuna Sakai
- YC Hwang
- Yoshimitsu Tanaka
- Yuya Fujishima
- Publication venue
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- Field of study
Infectious Bovine Rhinotracheitis / Vulvovaginitis (BHV1)
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- A Aguilar-Setién
- A Aguilar-Setién
- A Aguilar-Setién
- A Aguilar-Setién
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- A Schwers
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- A Wiseman
- A Zuffa
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- AE Metzler
- AE Metzler
- AJ Davison
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- AJ Tousimis
- AJF Schwartz
- AK Eugster
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- BD Hill
- BE Beck
- BE Sheffy
- BJ Carrillo
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- C Onyekaba
- C Riggenbach
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- C Terpstra
- CA Riegel
- CA Whetstone
- CE Bush
- CJ Kucera
- CJ York
- CL Kelling
- CN Hebert
- CO Darcel le
- CO Darcel le
- CP Bowling
- CP Peter
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- DC Bolton
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- DE Reed
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- DG McKercher
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- DL Rock
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- S Kit
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- TJ Hill
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- V Bitsch
- V Bitsch
- V Bitsch
- V Bitsch
- V Bitsch
- V Misra
- V Misra
- V Misra
- W Hammerschmidt
- W Hammerschmidt
- W Zwick
- WC Lawrence
- WC Rebhun
- WDG Yates
- WDG Yates
- WTK Hall
- Y Gilbert
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/1989
- Field of study