Wavelet Inverse Neutron Scattering Study of Layered Metallic NiC-Ti Composites

Composites are prevalent in high technology devices such as aircraft, computers, automobiles and communications systems. They improve brittleness and provide a lower density which enhances mechanical strength. Electron and light manipulating composites will be used more and more in the future. It is necessary to have a capability of inspecting composites, both to assure production quality and as a baseline for later NDE. In this paper, we present a study using wavelet, inverse neutron optics and the grazing angle neutron spectrometer, GANS, at the Missouri University Research Reactor, MURR

Enantioselective, intermolecular benzylic C–H amination catalysed by an engineered iron-haem enzyme

C–H bonds are ubiquitous structural units of organic molecules. Although these bonds are generally considered to be chemically inert, the recent emergence of methods for C–H functionalization promises to transform the way synthetic chemistry is performed. The intermolecular amination of C–H bonds represents a particularly desirable and challenging transformation for which no efficient, highly selective, and renewable catalysts exist. Here we report the directed evolution of an iron-containing enzymatic catalyst—based on a cytochrome P450 monooxygenase—for the highly enantioselective intermolecular amination of benzylic C–H bonds. The biocatalyst is capable of up to 1,300 turnovers, exhibits excellent enantioselectivities, and provides access to valuable benzylic amines. Iron complexes are generally poor catalysts for C–H amination: in this catalyst, the enzyme's protein framework confers activity on an otherwise unreactive iron-haem cofactor