22 research outputs found

    On the IC architecture and design of a 2 µm CMOS 8 MIPS digital signal processor with parallel processing capability: The PCB5010/5011

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    \u3cp\u3eA 2- mu m CMOS digital signal processor (PCB5010/PCB5011), capable of eight million instructions per second (8 MIPS) and up to six concurrent operations in each instruction is described. This high throughput results from a highly parallel architecture with high-speed data-handling capability. The processor contains two 16-b data buses, two primary execution units, five I/O interfaces, a data ROM, two data RAMs, and flexible addressing of on- and off-chip memory using three address computation units. Benchmarks show a two to six times improvement in overall performance over its predecessors.\u3c/p\u3

    PREDICTION OF RESIDUAL RETROPERITONEAL MASS HISTOLOGY AFTER CHEMOTHERAPY FOR METASTATIC NONSEMINOMATOUS GERM-CELL TUMOR - MULTIVARIATE-ANALYSIS OF INDIVIDUAL PATIENT DATA FROM 6 STUDY-GROUPS

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    Purpose: To develop a statistical model that predicts the histology (necrosis, mature teratoma, or cancer) after chemotherapy for metastatic nonseminomatous germ cell tumor (NSGCT). Patients and Methods: An international data was collected comprising individual patient data from six study groups. Logistic regression analysis was used to estimate the probability of necrosis and the ratio of cancer and mature teratoma. Results: Of 556 patients, 250 (45%) had necrosis at resection, 236 (42%) had mature teratoma, and 70 (13%) had cancer. Predictors of necrosis were the absence fo teratoma elements in the primary tumor, prechemotherapy normal alfa-fetoprotein (AFP), normal human chorionic gonadotropin (HCG), and elevated lactate dehydrogenase (LDH) levels, a small prechemotherapy or postchemotherapy mass, and a large shrinkage of the mass during chemotherapy. Multivariate combination of predictors yielded reliable models (goodness-of-fit tests, P > .20), which discriminated necrosis well from other histologies (area under the receiver operating characteristics (ROC) curve, .84), but which discriminated cancer only reasonably from mature teratoma (area, .66). Internal and external validation confirmed these findings. Conclusion: The validated models estimated with high accuracy the histology at resection, especially necrosis, based on well-known and readily available predictors. The predicted probabilities may help to chose between immediate resection of a residual mass or follow-up, taking into account the expected benefits and risks of resection, feasibility of frequent follow-up, the follow-up, the financial costs, and the patient's individual preferences

    Model driven architecture engineered land administration in conformance with international standards: illustrated with the Hellenic Cadastre

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    Background: Over the last years, the new role of Land Administration in realising the Information Infrastructure and the need to address spatial and non- spatial land related data exchange between countries emerged and since then, standard models were created and put into use. Two examples of these standards are the Land Administration Domain Model and INSPIRE's Cadastral Parcels. The former is an official international standard with a great deal of prospects; it is based on the 'people - land' relationship and has many applications apart from storingdata about properties. The latter is part of a specification framework (set of rules) describing how cadastral parcels can serve as reference for creating a European Spatial Data Infrastructure, enabling cross border dissemination ofdata. Methods: This paper provides the design of a conceptual model in conformance with both standards. Within this context a Land Administration Domain Model - compliant country profile and the INSPIRE model for Cadastral Parcels are proposed based on characteristic cases from the Hellenic Cadastre. Applying LADM brings along the collective international expertise on various aspects, which are analysed and applied for Greece: including administrative and spatial sources, supporting historical data (versioning), integration of legal (rights) and spatial data (cadastral map), including different register types (Archaeological, Urban, Rural, Forest), and allowing for an integrated 3D registration.Results: This research results in a model that can be used as a transition from the current cadastral system to a fully LADM- compliant one, taking also into account the INSPIRE directive. The paper further investigates how thedeveloped conceptual model, may be automatically converted to a technical model using Model Driven Architecture. Problematic issues and constraints are highlighted when applying the Model Driven Architecture approach and suggestions for resolving these issues are described.Conclusions: It is feasible to develop a conceptual model (country profile) which is in conformance with multiple standards, LADM and INSPIRE, because these are well aligned. Cross-boundary land administration is more than ever a very important requirement in todays’ global and European community. This is where the adoption of standards comes to play in realising the Information infrastructure.OLD Department of GIS Technolog
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