6 research outputs found
Additional Records of Tripletail Lobotes surinamensis (Bloch, 1790), from the Eastern Mediterranean
Origin of Agouti-Melanistic Polymorphism in Wild Black Rats (Rattus rattus) Inferred from Mc1r Gene Sequences
Incipient road to extinction of a keystone herbivore in south-eastern Europe: Harting’s vole (Microtus hartingi) under climate change
Mitochondrial channels: ion fluxes and more.
The field of mitochondrial ion channels has recently seen substantial progress, including the molecular identification of some of the channels. An integrative approach using genetics, electrophysiology, pharmacology, and cell biology to clarify the roles of these channels has thus become possible. It is by now clear that many of these channels are important for energy supply by the mitochondria and have a major impact on the fate of the entire cell as well. The purpose of this review is to provide an up-to-date overview of the electrophysiological properties, molecular identity, and pathophysiological functions of the mitochondrial ion channels studied so far and to highlight possible therapeutic perspectives based on current information