2,840 research outputs found
Potential of optimized NOvA for large theta(13) & combined performance with a LArTPC & T2K
NOvA experiment has reoptimized its event selection criteria in light of the
recently measured moderately large value of theta(13). We study the improvement
in the sensitivity to the neutrino mass hierarchy and to leptonic CP violation
due to these new features. For favourable values of deltacp, NOvA sensitivity
to mass hierarchy and leptonic CP violation is increased by 20%. Addition of 5
years of neutrino data from T2K to NOvA more than doubles the range of deltacp
for which the leptonic CP violation can be discovered, compared to stand alone
NOvA. But for unfavourable values of deltacp, the combination of NOvA and T2K
are not enough to provide even a 90% C.L. hint of hierarchy discovery.
Therefore, we further explore the improvement in the hierarchy and CP violation
sensitivities due to the addition of a 10 kt liquid argon detector placed close
to NOvA site. The capabilities of such a detector are equivalent to those of
NOvA in all respects. We find that combined data from 10 kt liquid argon
detector (3 years of nu + 3 years of nubar run), NOvA (6 years of nu + 6 years
of nubar run) and T2K (5 years of nu run) can give a close to 2 sigma hint of
hierarchy discovery for all values of deltacp. With this combined data, we can
achieve CP violation discovery at 95% C.L. for roughly 60% values of deltacp.Comment: 22 pages, 24 pdf figures, 5 tables. In the appendix, new results are
presented with conservative choices of central values of oscillation
parameters. New references are added. Accepted in JHE
Two- and three-point functions in two-dimensional Landau-gauge Yang-Mills theory: Continuum results
We investigate the Dyson-Schwinger equations for the gluon and ghost
propagators and the ghost-gluon vertex of Landau-gauge gluodynamics in two
dimensions. While this simplifies some aspects of the calculations as compared
to three and four dimensions, new complications arise due to a mixing of
different momentum regimes. As a result, the solutions for the propagators are
more sensitive to changes in the three-point functions and the ansaetze used
for them at the leading order in a vertex a expansion. Here, we therefore go
beyond this common truncation by including the ghost-gluon vertex
self-consistently for the first time, while using a model for the three-gluon
vertex which reproduces the known infrared asymptotics and the zeros at
intermediate momenta as observed on the lattice. A separate computation of the
three-gluon vertex from the results is used to confirm the stability of this
behavior a posteriori. We also present further arguments for the absence of the
decoupling solution in two dimensions. Finally, we show how in general the
infrared exponent kappa of the scaling solutions in two, three and four
dimensions can be changed by allowing an angle dependence and thus an essential
singularity of the ghost-gluon vertex in the infrared.Comment: 24 pages; added references, improved choices of parameters for vertex
models; identical to version published in JHE
Differential expression analysis for sequence count data
*Motivation:* High-throughput nucleotide sequencing provides quantitative readouts in assays for RNA expression (RNA-Seq), protein-DNA binding (ChIP-Seq) or cell counting (barcode sequencing). Statistical inference of differential signal in such data requires estimation of their variability throughout the dynamic range. When the number of replicates is small, error modelling is needed to achieve statistical power.

*Results:* We propose an error model that uses the negative binomial distribution, with variance and mean linked by local regression, to model the null distribution of the count data. The method controls type-I error and provides good detection power. 

*Availability:* A free open-source R software package, _DESeq_, is available from the Bioconductor project and from "http://www-huber.embl.de/users/anders/DESeq":http://www-huber.embl.de/users/anders/DESeq
A systematic review of biomarkers for disease progression in Parkinson's disease
Peer reviewedPublisher PD
Exploring New Physics in the C7-C7' plane
The Wilson coefficient C7 governing the radiative electromagnetic decays of B
meson has been calculated to a very high accuracy in the Standard Model, but
experimental bounds on either the magnitude or the sign of C7 are often
model-dependent. In the present paper, we attempt at constraining both the
magnitude and sign of C7 using a systematic approach. We consider already
measured observables like the branching ratios of B \rightarrow Xs mu+ mu- and
B \rightarrow Xs gamma, the isospin and CP asymmetries in B \rightarrow K*
gamma, as well as AFB and FL in B \rightarrow K*l+l-. We also discuss the
transverse observable AT2 which, once measured, may help to disentangle some of
the scenarios considered. We explore the constraints on C7, C9, C10 as well as
their chirality-flipped counterparts. Within our framework, we find that we
need to extend the constraints up to 1.6 sigma to allow for the "flipped-sign
solution" of C7. The SM solution for C7 exhibits a very mild tension if New
Physics is allowed in dipole operators only. We provide semi-numerical
expressions for all these observables as functions of the relevant Wilson
coefficients at the low scale.Comment: 54 pages, 16 figures, 15 tables. Normalization factor introduced for
the integrated AFB and FL in Sec.2.5 (Eq.2.35-2.38). Conclusions unchanged.
Not updated in JHE
Floral temperature and optimal foraging: is heat a feasible floral reward for pollinators?
As well as nutritional rewards, some plants also reward ectothermic pollinators with warmth. Bumble bees have some control over their temperature, but have been shown to forage at warmer flowers when given a choice, suggesting that there is some advantage to them of foraging at warm flowers (such as reducing the energy required to raise their body to flight temperature before leaving the flower). We describe a model that considers how a heat reward affects the foraging behaviour in a thermogenic central-place forager (such as a bumble bee). We show that although the pollinator should spend a longer time on individual flowers if they are warm, the increase in total visit time is likely to be small. The pollinator's net rate of energy gain will be increased by landing on warmer flowers. Therefore, if a plant provides a heat reward, it could reduce the amount of nectar it produces, whilst still providing its pollinator with the same net rate of gain. We suggest how heat rewards may link with plant life history strategies
The Relationship Between HR Practices and Firm Performance: Examining Causal Order
Significant research attention has been devoted to examining the relationship between HR practices and firm performance, and the research support has assumed HR as the causal variable. Using data from 45 business units (with 62 data points), this study examines how measures of HR practices correlate with past, concurrent, and future operational performance measures. The results indicate that correlations with performance measures at all three times are both high and invariant, and that controlling for past or concurrent performance virtually eliminates the correlation of HR with future performance. Implications are discussed
How many general and inflammatory variables need to be fulfilled when defining sepsis due to the 2003 SCCM/ESICM/ACCP/ATS/SIS definitions in critically ill surgical patients: a retrospective observational study
Endothelio-hematopoietic relationship: getting closer to the beginnings
The close association between hematopoietic and endothelial cells during embryonic development led to the proposal that they may originate from a common ancestor - the hemangioblast. Due to a lack of unique specific markers for in vivo cell fate tracking studies, evidence supporting this theory derives mainly from in vitro differentiation studies. Teixeira and colleagues describe a novel enhancer that drives specific eGFP expression in blood islands of the electroporated chick embryo, thereby presenting a tool potentially suitable for analysis of hemangioblast differentiation and development of blood islands
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