18 research outputs found
A RAPID, REVERSED PHASE LIQUID CHROMATOGRAPHIC TECHNIQUE FOR THE SIMULTANEOUS DETERMINATION OF CARBAMAZEPINE AND ITS 10, 11-EPOXIDE
Full text linkTricyclic drugs: potent mutagenicity of traces of a nitroarene formed in the reaction of opipramol with nitrite
Full text linkInfluence of Concurrent Administration of Sodium Valproate on the Plasma Concentrations of Carbamazepine and Its Epoxide and Diol Metabolites
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Synthesis and crystal structure of 5-allyl 5Hdibenzo [b,f]azepine
Full text linkThe crystals 5H-dibenzo[b,f]azepine 2 and 5-allyl-5H-dibenzo[b,f]azepine 3 were synthesized and characterized by X-ray crystallography. The compound 3 is a novel synthon for the construction of unusual isoxazoli(ne)dine rings bearing at the 5th position of dibenzo[b,f]azepine moiety. The compound 2 (C14H11N) crystallizes in the orthorhombic space group P212121 with the parameters a = 6.036(1) Å, b = 8.250(7) Å, c = 20.528(4) Å, Z = 4 and the final R factor is R1 = 0.0544. The compound 3 (C17H15N) crystallizes in the Hexagonal space group P61 with the parameters a = 11.043(9) Å, c = 18.575 Å, Z = 6 and the final R factor is R1 = 0.0373
Comparative oxidative metabolic profiles of clomipramine in cats, rats and dogs: preliminary results from an in vitro study
Full text linkPlasma concentration, mammary excretion and side-effects of phenylbutazone after repeated oral administration in healthy cows
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