185 research outputs found

    Acute pouchitis: the condition that time forgot about

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    The ileoanal pouch offers patients with medically refractory ulcerative colitis the opportunity to avoid a permanent ostomy and utilize their own bowel as a reservoir allowing a more ‘natural defaecation’. However, medical complications from inflammatory (pouchitis, pre-pouch ileitis and cuffitis) and non-inflammatory (irritable pouch syndrome) are common and negatively impact the quality of life (QoL)

    On operad structures of moduli spaces and string theory

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    Recent algebraic structures of string theory, including homotopy Lie algebras, gravity algebras and Batalin-Vilkovisky algebras, are deduced from the topology of the moduli spaces of punctured Riemann spheres. The principal reason for these structures to appear is as simple as the following. A conformal field theory is an algebra over the operad of punctured Riemann surfaces, this operad gives rise to certain standard operads governing the three kinds of algebras, and that yields the structures of such algebras on the (physical) state space naturally.Comment: 33 pages (An elaboration of minimal area metrics and new references are added

    Translation to practice: a randomised controlled study of an evidenced based booklet targeted at breast care nurses in the United Kingdom

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    BACKGROUND: In the United Kingdom (UK), it was documented that a problem of knowledge transfer existed within the speciality of breast-cancer care, thus depriving patients of receiving optimal care. Despite increasingly robust research evidence indicating recommendation of whole body exercise for people affected by breast cancer, commensurate changes to practice were not noted amongst breast-care nurses (BCNs). AIM: To evaluate the effect of a targeted booklet, Exercise and Breast Cancer: A Booklet for Breast-Care Nurses, on changes in knowledge, reported practice, and attitudes of BCNs in the UK. METHOD: A prospective, experimental approach was used for designing a pre- and post-test randomised controlled study. Comparisons of knowledge, reported practice, and attitudes based on responses to a questionnaire were made at two time-points in two groups of BCNs (control and experimental). The unit of randomisation and analysis was hospital clusters of BCNs. The sample comprised 92 nurses from 62 hospitals. Analysis consisted of descriptive statistics and clustered regression techniques: clustered logistic regression for knowledge items, clustered linear regression for knowledge scores, ologit for attitude and reported practice items, and clustered multiple regression for paired and multiple variable analysis. RESULTS: A statistically significant increase in knowledge and changes in reported practice and attitudes were found. Robust variables affecting knowledge acquisition were: promotion of health, promotion of exercise, and understanding how exercise can reduce cancer-related fatigue. DISCUSSION: The study has shown that evidence-based printed material, such as an information booklet, can be used as an effective research dissemination method when developed for needs, values, and context of a target audience. CONCLUSIONS: This practical approach to research dissemination could be replicated and applied to other groups of nurses.</p

    Current-Induced Effects in Nanoscale Conductors

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    We present an overview of current-induced effects in nanoscale conductors with emphasis on their description at the atomic level. In particular, we discuss steady-state current fluctuations, current-induced forces, inelastic scattering and local heating. All of these properties are calculated in terms of single-particle wavefunctions computed using a scattering approach within the static density-functional theory of many-electron systems. Examples of current-induced effects in atomic and molecular wires will be given and comparison with experimental results will be provided when available.Comment: revtex, 10 pages, 8 figure

    On Global Aspects Of Gauged Wess-Zumino-Witten Model

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    This is a thesis for Rigaku-Hakushi(\simeq Ph. D.). It clarifies the geometric meaning and field theoretical consequences of the spectral flows acting on the space of states of the `G/HG/H coset model'. As suggested by Moore and Seiberg, the spectral flow is realized as the response of states to certain change of background gauge field together with the gauge transformation on a circle. Applied to the boundary circle of a disc with field insertion, such a realization leads to a certain relation among correlators of the gauged WZW model for various principal HH-bundles. In the course of derivation, we find an expression of a (dressed) gauge invariant field as an integral over the flag manifold of HH and an expression of a correlator as an integral over a certain moduli space of holomorphic HCH_{\bf C}-bundles with quasi-flag structure at the insertion point. We also find that the gauge transformation on the circle corresponding to the spectral flow determines a bijection of the set of isomorphism classes of holomorphic HCH_{\bf C}-bundles with quasi-flag structure of one topological type to that of another. As an application, it is pointed out that problems arising from the field identification fixed points may be resolved by taking into account of all principal HH-bundles.Comment: (Thesis) 125 pages, UT-Komaba/94-3 (Latex errors are corrected

    Hamstring muscles: Architecture and innervation

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    Knowledge of the anatomical organization of the hamstring muscles is necessary to understand their functions, and to assist in the development of accurate clinical and biomechanical models. The hamstring muscles were examined by dissection in six embalmed human lower limbs with the purpose of clarifying their gross morphology. In addition to obtaining evidence for or against anatomical partitioning ( as based on muscle architecture and pattern of innervation), data pertaining to architectural parameters such as fascicular length, volume, physiological cross-sectional area, and tendon length were collected. For each muscle, relatively consistent patterns of innervation were identified between specimens, and each was unique with respect to anatomical organization. On the basis of muscle architecture, three regions were identified within semimembranosus. However, this was not completely congruent with the pattern of innervation, as a primary nerve branch supplied only two regions, with the third region receiving a secondary branch. Semitendinosus comprised two distinct partitions arranged in series that were divided by a tendinous inscription. A singular muscle nerve or a primary nerve branch innervated each partition. In the biceps femoris long head the two regions were supplied via a primary nerve branch which divided into two primary branches or split into a series of branches. Being the only muscle to cross a single joint, biceps femoris short head consisted of two distinct regions demarcated by fiber direction, with each innervated by a separate muscle nerve. Architecturally, each muscle differed with respect to parameters such as physiological cross-sectional area, fascicular length and volume, but generally all partitions within an individual muscle were similar in fascicular length. The long proximal and distal tendons of these muscles extended into the muscle bellies thereby forming elongated musculotendinous junctions. Copyright (C) 2005 S. Karger AG, Basel
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