The effect of work pace on workload, motor variability and fatigue during simulated light assembly work

This study investigated the effect of work pace on workload, motor variability and fatigue during light assembly work. Upper extremity kinematics and electromyography (EMG) were obtained on a cycle-to-cycle basis for eight participants during two conditions, corresponding to "normal" and "high" work pace according to a predetermined time system for engineering. Indicators of fatigue, pain sensitivity and performance were recorded before, during and after the task. The level and variability of muscle activity did not differ according to work pace, and manifestations of muscle fatigue or changed pain sensitivity were not observed. In the high work pace, however, participants moved more efficiently, they showed more variability in wrist speed and acceleration, but they also made more errors. These results suggest that an increased work pace, within the range addressed here, will not have any substantial adverse effects on acute motor performance and fatigue in light, cyclic assembly work. © 2011 Taylor & Francis

EUSO-SPB2 Telescope Optics and Testing

The Extreme Universe Space Observatory - Super Pressure Balloon (EUSO-SPB2) mission will fly two custom telescopes that feature Schmidt optics to measure Cherenkov- and fluorescence emission of extensive air showers from cosmic rays at the PeV and EeV-scale, and search for τ-neutrinos. Both telescopes have 1-meter diameter apertures and UV/UV-visible sensitivity. The Cherenkov telescope uses a bifocal mirror segment alignment, to distinguish between a direct cosmic ray that hits the camera versus the Cherenkov light from outside the telescope. Telescope integration and laboratory calibration will be performed in Colorado. To estimate the point spread function and efficiency of the integrated telescopes, a test beam system that delivers a 1-meter diameter parallel beam of light is being fabricated. End-to-end tests of the fully integrated instruments will be carried out in a field campaign at dark sites in the Utah desert using cosmic rays, stars, and artificial light sources. Laser tracks have long been used to characterize the performance of fluorescence detectors in the field. For EUSO-SPB2 an improvement in the method that includes a correction for aerosol attenuation is anticipated by using a bi-dynamic Lidar configuration in which both the laser and the telescope are steerable. We plan to conduct these field tests in Fall 2021 and Spring 2022 to accommodate the scheduled launch of EUSO-SPB2 in 2023 from Wanaka, New Zealand

Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: 5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. INTERPRETATION: International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems

Exploring interactive systems using peripheral sounds

Our everyday interaction in and with the physical world, has facilitated the development of auditory perception skills that enable us to selectively place one auditory channel in the center of our attention and simultaneously monitor others in the periphery. We search for ways to leverage these auditory perception skills in interactive systems. In this paper, we present three working demonstrators that use sound to subtly convey information to users in an open office. To qualitatively evaluate these demonstrators, each of them has been implemented in an office for three weeks. We have seen that such a period of time, sounds can start shifting from the center to the periphery of the attention. Furthermore, we found several issues to be addressed when designing such systems, which can inform future work in this area

The Extended Continental Crust West of Islas Marías (Mexico)

The crustal structure around the Islas Marías Archipelago has been debated for a long time. An important unresolved question is where the Rivera-North American plate subduction ends and the Tamayo fracture zone begins, from SE to NW. Results from the TsuJal project have shed light on the northwesternmost part of the Jalisco block structure. It is now clear that Sierra de Cleofas and the Islas Marías Escarpment comprise the northwestern continuation of the Middle America trench. However, other questions remain. In this paper, we present the structure of the shallow and deep crust and the upper mantle of the Islas Marías western region through the integration of multichannel seismic reflection, wide-angle seismic bathymetric and seismicity data, including records of an amphibious seismic network, OBS, and portable seismic stations, purposely deployed for this project, providing an onshore-offshore transect of 310 km length. Our findings disclose new evidence of the complex structure of the Rivera plate that dips 8°–9° underneath the NW Jalisco block as revealed by two seismic profiles parallel to the Islas Marías Escarpment. Moreover, we find five sedimentary basins and active normal faults at the edges of tectonic structures of the E-W oriented West Ranges and the N-S trending Sierra de Cleofas. Furthermore, the Sierra de Cleofas is the beginning of the active subduction of the Rivera plate beneath North America. The oceanic crust thickens and submerges towards the south while is coupled with the continental crust, from 6 km at the northern ends of the seismic profiles to 15 km in the contact region and 24 km at the coast and southern ends of them. The continental Moho was not fully characterized because of the geometry of the seismic transects, but a low-velocity layer associated with Rivera Plate subduction was observed beneath the Jalisco Block. Our results constrain the complexity of the area and reveal new structural features from the oceanic to continental crust and will be pivotal to assess geohazards in this area.</jats:p

Does solar exposure, as indicated by the non-melanoma skin cancers, protect from solid cancers: Vitamin D as a possible explanation

10.1016/j.ejca.2007.04.018European Journal of Cancer43111701-1712EJCA

Associations between ocular melanoma and other primary cancers: An international population-based study

10.1002/ijc.22159International Journal of Cancer1201152-159IJCN

A pooled analysis of second primary pancreatic cancer

10.1093/aje/kwj073American Journal of Epidemiology1636502-511AJEP