138 research outputs found
Child witchcraft confessions as an idiom of distress in Sierra Leone; results of a rapid qualitative inquiry and recommendations for mental health interventions
Phenotypic effects of calving ease on the subsequent fertility and milk production of dam and calf in UK Holstein-Friesian heifers
The bowfin genome illuminates the developmental evolution of ray-finned fishes.
The bowfin (Amia calva) is a ray-finned fish that possesses a unique suite of ancestral and derived phenotypes, which are key to understanding vertebrate evolution. The phylogenetic position of bowfin as a representative of neopterygian fishes, its archetypical body plan and its unduplicated and slowly evolving genome make bowfin a central species for the genomic exploration of ray-finned fishes. Here we present a chromosome-level genome assembly for bowfin that enables gene-order analyses, settling long-debated neopterygian phylogenetic relationships. We examine chromatin accessibility and gene expression through bowfin development to investigate the evolution of immune, scale, respiratory and fin skeletal systems and identify hundreds of gene-regulatory loci conserved across vertebrates. These resources connect developmental evolution among bony fishes, further highlighting the bowfin's importance for illuminating vertebrate biology and diversity in the genomic era
Epigenetic control of nuclear architecture
The cell nucleus is a highly structured compartment where nuclear components are thought to localize in non-random positions. Correct positioning of large chromatin domains may have a direct impact on the localization of other nuclear components, and can therefore influence the global functionality of the nuclear compartment. DNA methylation of cytosine residues in CpG dinucleotides is a prominent epigenetic modification of the chromatin fiber. DNA methylation, in conjunction with the biochemical modification pattern of histone tails, is known to lock chromatin in a close and transcriptionally inactive conformation. The relationship between DNA methylation and large-scale organization of nuclear architecture, however, is poorly understood. Here we briefly summarize present concepts of nuclear architecture and current data supporting a link between DNA methylation and the maintenance of large-scale nuclear organization
Thermal Evolution and Magnetic Field Generation in Terrestrial Planets and Satellites
RelaçÔes entre tamanho de sedimentos erodidos, velocidade da enxurrada, rugosidade superficial criada pelo preparo e tamanho de agregados em solo submetido a diferentes manejos
Redução da poda hibernal e aumento da produção de pereiras 'Hosui' pelo uso de prohexadiona cålcio
Atividade residual de herbicidas usados na soja sobre o girassol cultivado em sucessĂŁo
Estrutura e armazenamento de ĂĄgua em um Argissolo sob pastagem cultivada, floresta nativa e povoamento de eucalipto no Rio Grande do Sul
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