12,278 research outputs found
Significance Analysis for Pairwise Variable Selection in Classification
The goal of this article is to select important variables that can
distinguish one class of data from another. A marginal variable selection
method ranks the marginal effects for classification of individual variables,
and is a useful and efficient approach for variable selection. Our focus here
is to consider the bivariate effect, in addition to the marginal effect. In
particular, we are interested in those pairs of variables that can lead to
accurate classification predictions when they are viewed jointly. To accomplish
this, we propose a permutation test called Significance test of Joint Effect
(SigJEff). In the absence of joint effect in the data, SigJEff is similar or
equivalent to many marginal methods. However, when joint effects exist, our
method can significantly boost the performance of variable selection. Such
joint effects can help to provide additional, and sometimes dominating,
advantage for classification. We illustrate and validate our approach using
both simulated example and a real glioblastoma multiforme data set, which
provide promising results.Comment: 28 pages, 7 figure
Interaction between a fast rotating sunspot and ephemeral regions as the origin of the major solar event on 2006 December 13
The major solar event on 2006 December 13 is characterized by the
approximately simultaneous occurrence of a heap of hot ejecta, a great
two-ribbon flare and an extended Earth-directed coronal mass ejection. We
examine the magnetic field and sunspot evolution in active region NOAA AR
10930, the source region of the event, while it transited the solar disk centre
from Dec. 10 to Dec. 13. We find that the obvious changes in the active region
associated with the event are the development of magnetic shear, the appearance
of ephemeral regions and fast rotation of a smaller sunspot. Around the area of
the magnetic neutral line of the active region, interaction between the fast
rotating sunspot and the ephemeral regions triggers continual brightening and
finally the major flare. It is indicative that only after the sunspot rotates
up to 200 does the major event take place. The sunspot rotates at
least 240 about its centre, the largest sunspot rotation angle which
has been reported.Comment: 4 pages, 6 figures, ApJ Letters inpres
Two-stage clustering in genotype-by-environment analyses with missing data
Cluster analysis has been commonly used in genotype-by-environment (G x E) analyses, but current methods are inadequate when the data matrix is incomplete. This paper proposes a new method, referred to as two-stage clustering, which relies on a partitioning of squared Euclidean distance into
two independent components, the G x E interaction and the genotype main effect. These components are used in the first and second stages of clustering respectively. Two-stage clustering forms the basis for imputing missing values in the G x E matrix so that a more complete data array is available for other GxE analyses. Imputation for a given genotype uses information from genotypes with similar interaction profiles. This imputation method is shown to improve on an existing nearest cluster method that confounds the G x E interaction and the genotype main effect
Effect of myocardial preservation of early goal-directed therapy on severe sepsis/septic shock patients in the ICU
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