11 research outputs found
The bc 1 complexes of Rhodobacter sphaeroides and Rhodobacter capsulatus
Photosynthetic bacteria offer excellent experimental opportunities to explore both the structure and function of the ubiquinol-cytochrome c oxidoreductase ( bc 1 complex). In both Rhodobacter sphaeroides and Rhodobacter capsulatus , the bc 1 complex functions in both the aerobic respiratory chain and as an essential component of the photosynthetic electron transport chain. Because the bc 1 complex in these organisms can be functionally coupled to the photosynthetic reaction center, flash photolysis can be used to study electron flow through the enzyme and to examine the effects of various amino acid substitutions. During the past several years, numerous mutations have been generated in the cytochrome b subunit, in the Rieske iron-sulfur subunit, and in the cytochrome c 1 subunit. Both site-directed and random mutagenesis procedures have been utilized. Studies of these mutations have identified amino acid residues that are metal ligands, as well as those residues that are at or near either the quinol oxidase (Q o ) site or the quinol reductase (Q i ) site. The postulate that these two Q-sites are located on opposite sides of the membrane is supported by these studies. Current research is directed at exploring the details of the catalytic mechanism, the nature of the subunit interactions, and the assembly of this enzyme.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/44795/1/10863_2004_Article_BF00762582.pd
Topographical organization of cytochrome b6 in the thylakoid membrane of spinach chloroplasts determined by fluorescence studies with N-cyclohexyl-N'-[4-(dimethylamino)naphthyl]carbodiimide
Characterisation of binding of the methoxyacrylate inhibitors to mitochondrial cytochrome c reductase
Assessment of Sensitivities to Anilinopyrimidine- and Strobilurin-fungicides in Populations of the Apple Scab Fungus Venturia inaequalis
Transcriptional analysis of the Staphylococcus aureus plasmid pI258 mercury resistance determinant
The unusual reversion properties of a mitochondrial mutation in the structural gene of subunit I of cytochrome oxidase of Saccharomyces cerevisiae reveal a probable histidine ligand of the redox center
An Erg-driven transcriptional program controls B cell lymphopoiesis
B cell development is tightly regulated in a stepwise manner to ensure proper generation of repertoire diversity via somatic gene rearrangements. Here, the authors show that a transcription factor, Erg, functions at the earliest stage to critically control two downstream factors, Ebf1 and Pax5, for modulating this gene rearrangement process
Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia
ISSN:1934-5909ISSN:1875-977