13,646 research outputs found

    Bridging the Gap between Probabilistic and Deterministic Models: A Simulation Study on a Variational Bayes Predictive Coding Recurrent Neural Network Model

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    The current paper proposes a novel variational Bayes predictive coding RNN model, which can learn to generate fluctuated temporal patterns from exemplars. The model learns to maximize the lower bound of the weighted sum of the regularization and reconstruction error terms. We examined how this weighting can affect development of different types of information processing while learning fluctuated temporal patterns. Simulation results show that strong weighting of the reconstruction term causes the development of deterministic chaos for imitating the randomness observed in target sequences, while strong weighting of the regularization term causes the development of stochastic dynamics imitating probabilistic processes observed in targets. Moreover, results indicate that the most generalized learning emerges between these two extremes. The paper concludes with implications in terms of the underlying neuronal mechanisms for autism spectrum disorder and for free action.Comment: This paper is accepted the 24th International Conference On Neural Information Processing (ICONIP 2017). The previous submission to arXiv is replaced by this version because there was an error in Equation

    New Measurement of the Relative Scintillation Efficiency of Xenon Nuclear Recoils Below 10 keV

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    Liquid xenon is an important detection medium in direct dark matter experiments, which search for low-energy nuclear recoils produced by the elastic scattering of WIMPs with quarks. The two existing measurements of the relative scintillation efficiency of nuclear recoils below 20 keV lead to inconsistent extrapolations at lower energies. This results in a different energy scale and thus sensitivity reach of liquid xenon dark matter detectors. We report a new measurement of the relative scintillation efficiency below 10 keV performed with a liquid xenon scintillation detector, optimized for maximum light collection. Greater than 95% of the interior surface of this detector was instrumented with photomultiplier tubes, giving a scintillation yield of 19.6 photoelectrons/keV electron equivalent for 122 keV gamma rays. We find that the relative scintillation efficiency for nuclear recoils of 5 keV is 0.14, staying constant around this value up to 10 keV. For higher energy recoils we measure a value around 20%, consistent with previously reported data. In light of this new measurement, the XENON10 experiment's results on spin-independent WIMP-nucleon cross section, which were calculated assuming a constant 0.19 relative scintillation efficiency, change from 8.8×10−448.8\times10^{-44} cm2^2 to 9.9×10−449.9\times10^{-44} cm2^2 for WIMPs of mass 100 GeV/c2^2, and from 4.4×10−444.4\times10^{-44} cm2^2 to 5.6×10−445.6\times10^{-44} cm2^2 for WIMPs of mass 30 GeV/c2^2.Comment: 8 pages, 8 figure

    Stabilization of the number of Bose-Einstein condensed atoms in evaporative cooling via three-body recombination loss

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    The dynamics of evaporative cooling of magnetically trapped 87^{87}Rb atoms is studied on the basis of the quantum kinetic theory of a Bose gas. We carried out the quantitative calculations of the time evolution of conventional evaporative cooling where the frequency of the radio-frequency magnetic field is swept exponentially. This "exponential-sweep cooling" is known to become inefficient at the final stage of the cooling process due to a serious three-body recombination loss. We precisely examine how the growth of a Bose-Einstein condensate depends on the experimental parameters of evaporative cooling, such as the initial number of trapped atoms, the initial temperature, and the bias field of a magnetic trap. It is shown that three-body recombination drastically depletes the trapped 87^{87}Rb atoms as the system approaches the quantum degenerate region and the number of condensed atoms finally becomes insensitive to these experimental parameters. This result indicates that the final number of condensed atoms is well stabilized by a large nonlinear three-body loss against the fluctuations of experimental conditions in evaporative cooling.Comment: 7 pages, REVTeX4, 8 eps figures, Phys. Rev A in pres

    Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking

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    We have previously reported that galectin-4, a tandem repeat-type galectin, regulates the raft-dependent delivery of glycoproteins to the apical brush border membrane of enterocyte-like HT-29 cells. N-Acetyllactosamine-containing glycans, known as galectin ligands, were found enriched in detergent-resistant membranes. Here, we analyzed the potential contribution of N-and/ or O-glycans in this mechanism. Structural studies were carried out on the brush border membrane-enriched fraction using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and nano-ESI-QTOF-MS/MS. The pattern of N-glycans was very heterogeneous, with the presence of high mannose- and hybrid-type glycans as well as a multitude of complex-type glycans. In contrast, the pattern of O-glycans was very simple with the presence of two major core type 1 O-glycans, sialylated and bisialylated T-antigen structures {[}Neu5Ac alpha 2-3Gal beta 1-3GalNAc-ol and Neu5Ac alpha 2-3Gal beta 1 -3(Neu5Ac alpha 2-6)GalNAc-ol]. Thus, N-glycans rather than O-glycans contain the N-acetyllactosamine recognition signals for the lipid raft-based galectin-4-dependent apical delivery. In the presence of 1-deoxymannojirimycin, a drug which inhibits the generation of hybrid-type or complex type N-glycans, the extensively O-glycosylated mucin-like MUC1 glycoprotein was not delivered to the apical brush border but accumulated inside the cells. Altogether, our data demonstrate the crucial role of complex N-glycans in the galectin-4-dependent delivery of glycoproteins to the apical brush border membrane of enterocytic HT-29 cells

    Parity-broken ground state for the spin-1 pyrochlore antiferromagnet

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    The ground-state properties of the spin-1 pyrochlore antiferromagnet are studied by applying the VBS-like tetrahedron-unit decomposition to the original spin system. The symmetrization required on every vertex is taken into account by introducing a ferromagnetic coupling. The pairwise effective Hamiltonian between the adjacent tetrahedrons is obtained by considering the next nearest neighbor and the third neighbor exchange interactions. We find that the transverse component of the spin chirality exhibits a long-range order, breaking the parity symmetry of the tetrahedral group, while the chirality itself is not broken.Comment: 4 pages, 3 figures, REVTeX(ver.3.1
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