47 research outputs found
On the ternary complex analysis and its applications
Previouly a possible extension of the complex number, together with its
connected trigonometry was introduced. In this paper we focuss on the simplest
case of ternary complex numbers. Then, some types of holomorphicity adapted to
the ternary complex numbers and the corresponding results upon integration of
differential forms are given. Several physical applications are given, and in
particuler one type of holomorphic function gives rise to a new form of
stationary magnetic field. The movement of a monopole type object in this field
is then studied and shown to be integrable. The monopole scattering in the
ternary field is finally studied.Comment: LaTeX 28 page
Two images of Nantes as a ‘Green Model’ of Urban Planning and Governance: The ‘Collaborative City’ Versus the ‘Slow City’
This article examines how the city of Nantes, European Green Capital in 2013, came to promote plans for a new international airport at Notre-Dame-des-Landes. Deploying poststructuralist discourse theory, it analyses how the highly politicised struggle against the airport reveals the limits of the Nantes model of urban sustainability and collaboration, giving rise to a counter model, which we provisionally characterise as the ‘slow city’. While the struggle against the airport can be understood as a rural social movement, we show how its ideals and logics have been progressively displaced to Nantes itself, disclosing new images and possibilities of urban governance
PLS3 Missense Variants Affecting the Actin-Binding Domains Cause X-Linked Congenital Diaphragmatic Hernia and Body-Wall Defects
Congenital diaphragmatic hernia (CDH) is a relatively common and genetically heterogeneous structural birth defect associated with high mortality and morbidity. We describe eight unrelated families with an X-linked condition characterized by diaphragm defects, variable anterior body-wall anomalies, and/or facial dysmorphism. Using linkage analysis and exome or genome sequencing, we found that missense variants in plastin 3 (PLS3), a gene encoding an actin bundling protein, co-segregate with disease in all families. Loss-of-function variants in PLS3 have been previously associated with X-linked osteoporosis (MIM: 300910), so we used in silico protein modeling and a mouse model to address these seemingly disparate clinical phenotypes. The missense variants in individuals with CDH are located within the actin-binding domains of the protein but are not predicted to affect protein structure, whereas the variants in individuals with osteoporosis are predicted to result in loss of function. A mouse knockin model of a variant identified in one of the CDH-affected families, c.1497G\u3eC (p.Trp499Cys), shows partial perinatal lethality and recapitulates the key findings of the human phenotype, including diaphragm and abdominal-wall defects. Both the mouse model and one adult human male with a CDH-associated PLS3 variant were observed to have increased rather than decreased bone mineral density. Together, these clinical and functional data in humans and mice reveal that specific missense variants affecting the actin-binding domains of PLS3 might have a gain-of-function effect and cause a Mendelian congenital disorder
Kinetics of the Reaction of Methyl Iodide with Hydroxylamine in an Aqueous Solution within the Framework of Nuclear Spent Fuel Reprocessing
International audienc
Caractérisation de films PVDF par spectroscopie Raman : une étude off-line vers une étude on-line
National audienc