845 research outputs found

    Coagulation and fragmentation processes with evolving size and shape profiles : a semigroup approach

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    We investigate a class of bivariate coagulation-fragmentation equations. These equations describe the evolution of a system of particles that are characterised not only by a discrete size variable but also by a shape variable which can be either discrete or continuous. Existence and uniqueness of strong solutions to the associated abstract Cauchy problems are established by using the theory of substochastic semigroups of operators

    Helium, Oxygen, Proton, and Electron (HOPE) Mass Spectrometer for the Radiation Belt Storm Probes Mission

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    The HOPE mass spectrometer of the Radiation Belt Storm Probes (RBSP) mission (renamed the Van Allen Probes) is designed to measure the in situ plasma ion and electron fluxes over 4π sr at each RBSP spacecraft within the terrestrial radiation belts. The scientific goal is to understand the underlying physical processes that govern the radiation belt structure and dynamics. Spectral measurements for both ions and electrons are acquired over 1 eV to 50 keV in 36 log-spaced steps at an energy resolution ΔE FWHM/E≈15 %. The dominant ion species (H+, He+, and O+) of the magnetosphere are identified using foil-based time-of-flight (TOF) mass spectrometry with channel electron multiplier (CEM) detectors. Angular measurements are derived using five polar pixels coplanar with the spacecraft spin axis, and up to 16 azimuthal bins are acquired for each polar pixel over time as the spacecraft spins. Ion and electron measurements are acquired on alternate spacecraft spins. HOPE incorporates several new methods to minimize and monitor the background induced by penetrating particles in the harsh environment of the radiation belts. The absolute efficiencies of detection are continuously monitored, enabling precise, quantitative measurements of electron and ion fluxes and ion species abundances throughout the mission. We describe the engineering approaches for plasma measurements in the radiation belts and present summaries of HOPE measurement strategy and performance

    Borderline Aggregation Kinetics in ``Dry'' and ``Wet'' Environments

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    We investigate the kinetics of constant-kernel aggregation which is augmented by either: (a) evaporation of monomers from finite-mass clusters, or (b) continuous cluster growth -- \ie, condensation. The rate equations for these two processes are analyzed using both exact and asymptotic methods. In aggregation-evaporation, if the evaporation is mass conserving, \ie, the monomers which evaporate remain in the system and continue to be reactive, the competition between evaporation and aggregation leads to several asymptotic outcomes. For weak evaporation, the kinetics is similar to that of aggregation with no evaporation, while equilibrium is quickly reached in the opposite case. At a critical evaporation rate, the cluster mass distribution decays as k5/2k^{-5/2}, where kk is the mass, while the typical cluster mass grows with time as t2/3t^{2/3}. In aggregation-condensation, we consider the process with a growth rate for clusters of mass kk, LkL_k, which is: (i) independent of kk, (ii) proportional to kk, and (iii) proportional to kμk^\mu, with 0<μ<10<\mu<1. In the first case, the mass distribution attains a conventional scaling form, but with the typical cluster mass growing as tlntt\ln t. When LkkL_k\propto k, the typical mass grows exponentially in time, while the mass distribution again scales. In the intermediate case of LkkμL_k\propto k^\mu, scaling generally applies, with the typical mass growing as t1/(1μ)t^{1/(1-\mu)}. We also give an exact solution for the linear growth model, LkkL_k\propto k, in one dimension.Comment: plain TeX, 17 pages, no figures, macro file prepende

    Cover Crop Effect on Subsequent Wheat Yield in the Central Great Plains

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    Crop production systems in the water-limited environment of the semiarid central Great Plains may not have potential to profitably use cover crops because of lowered subsequent wheat (Triticum asestivum L.) yields following the cover crop. Mixtures have reportedly shown less yield-reducing effects on subsequent crops than single-species plantings. This study was conducted to determine winter wheat yields following both mixtures and single-species plantings of spring-planted cover crops. The study was conducted at Akron, CO, and Sidney, NE, during the 2012–2013 and 2013–2014 wheat growing seasons under both rainfed and irrigated conditions. Precipitation storage efficiency before wheat planting, wheat water use, biomass, and yield were measured and water use efficiency and harvest index were calculated for wheat following four single-species cover crops (flax [Linum usitatissimum L.], oat [Avena sativa L.], pea [Pisum sativum ssp. arvense L. Poir], rapeseed [Brassica napus L.]), a 10-species mixture, and a fallow treatment with proso millet (Panicum miliaceum L.) residue. There was an average 10% reduction in wheat yield following a cover crop compared with following fallow, regardless of whether the cover crop was grown in a mixture or in a single-species planting. Yield reductions were greater under drier conditions. The slope of the wheat water use–yield relationship was not significantly different for wheat following the mixture (11.80 kg ha–1 mm–1) than for wheat following single-species plantings (12.32–13.57 kg ha–1 mm–1). The greater expense associated with a cover crop mixture compared with a single species is not justified

    Role of DLC-1, a tumor suppressor protein with RhoGAP activity, in regulation of the cytoskeleton and cell motility

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    DLC-1 was originally identified as a potential tumor suppressor. One of the key biochemical functions of DLC-1 is to serve as a GTPase activating protein (GAP) for members of the Rho family of GTPases, particularly Rho A-C and Cdc 42. Since these GTPases are critically involved in regulation of the cytoskeleton and cell migration, it seems clear that DLC-1 will also influence these processes. In this review we examine basic aspects of the actin cyoskeleton and how it relates to cell motility. We then delineate the characteristics of DLC-1 and other members of its family, and describe how they may have multiple effects on the regulation of cell polarity, actin organization, and cell migration

    Denying humanness to victims: How gang members justify violent behavior

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    The high prevalence of violent offending amongst gang-involved youth has been established in the literature. Yet the underlying psychological mechanisms that enable youth to engage in such acts of violence remain unclear. 189 young people were recruited from areas in London, UK, known for their gang activity. We found that gang members, in comparison to non-gang youth, described the groups they belong to as having recognized leaders, specific rules and codes, initiation rituals, and special clothing. Gang members were also more likely than non-gang youth to engage in violent behavior and endorse moral disengagement strategies (i.e., moral justification, euphemistic language, advantageous comparison, displacement of responsibility, attribution of blame, and dehumanization). Finally, we found that dehumanizing victims partially mediated the relationship between gang membership and violent behavior. These findings highlight the effects of groups at the individual level and an underlying psychological mechanism that explains, in part, how gang members engage in violence

    Effect of spatial bias on the nonequilibrium phase transition in a system of coagulating and fragmenting particles

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    We examine the effect of spatial bias on a nonequilibrium system in which masses on a lattice evolve through the elementary moves of diffusion, coagulation and fragmentation. When there is no preferred directionality in the motion of the masses, the model is known to exhibit a nonequilibrium phase transition between two different types of steady states, in all dimensions. We show analytically that introducing a preferred direction in the motion of the masses inhibits the occurrence of the phase transition in one dimension, in the thermodynamic limit. A finite size system, however, continues to show a signature of the original transition, and we characterize the finite size scaling implications of this. Our analysis is supported by numerical simulations. In two dimensions, bias is shown to be irrelevant.Comment: 7 pages, 7 figures, revte

    p120Ras-GAP binds the DLC1 Rho-GAP tumor suppressor protein and inhibits its RhoA GTPase and growth-suppressing activities

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    DLC1, which encodes a Rho GTPase activating protein (Rho-GAP), is a potent tumor suppressor gene that is frequently inactivated in several human cancers. DLC-1 is a multidomain protein that has been shown previously to bind members of the tensin gene family. Here we show that p120Ras-GAP (Ras-GAP; also known as RASA1) interacts and extensively colocalizes with DLC1 in focal adhesions. The binding was mapped to the SH3 domain located in the N-terminus of Ras-GAP and to the RhoGAP catalytic domain, located in the C-terminus of the DLC1. In vitro analyses with purified proteins determined that the isolated Ras-GAP SH3 domain inhibits DLC1 RhoGAP activity, suggesting that Ras-GAP is a negative regulator of DLC1 RhoGAP activity. Consistent with this possibility, we found that ectopic overexpression of Ras-GAP in a Ras-GAP-insensitive tumor line impaired the growth suppressing activity of DLC1 and increased RhoA activity in vivo. Our observations expand the complexity of proteins that regulate DLC1 function and define a novel mechanism of the cross-talk between Ras and Rho GTPases

    Mejora de la plataforma de e-learning Moodle utilizando redes neuronales

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    El presente trabajo describe las mejoras posibles de implementar sobre la plataforma de e-learning Moodle. En la primera parte se menciona la situación actual de la utilización de la plataforma. En la segunda, se plantean las ventajas y desventajas del uso de Moodle. En la tercera parte, se presenta el modelado de usuario como alternativa para la personalización de contenidos y se describe el modelo de red neuronal a utilizar para la adaptación de perfiles de estudiantes.Red de Universidades con Carreras en Informática (RedUNCI
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