72 research outputs found
The stepping stone model. II: Genealogies and the infinite sites model
This paper extends earlier work by Cox and Durrett, who studied the
coalescence times for two lineages in the stepping stone model on the
two-dimensional torus. We show that the genealogy of a sample of size n is
given by a time change of Kingman's coalescent. With DNA sequence data in mind,
we investigate mutation patterns under the infinite sites model, which assumes
that each mutation occurs at a new site. Our results suggest that the spatial
structure of the human population contributes to the haplotype structure and a
slower than expected decay of genetic correlation with distance revealed by
recent studies of the human genome.Comment: Published at http://dx.doi.org/10.1214/105051604000000701 in the
Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute
of Mathematical Statistics (http://www.imstat.org
Elective Modernism and the Politics of (Bio) Ethical Expertise
In this essay I consider whether the political perspective of third wave science studies – ‘elective modernism’ – offers a suitable framework for understanding the policy-making contributions that (bio)ethical experts might make. The question arises as a consequence of the fact that I have taken inspiration from the third wave in order to develop an account of (bio)ethical expertise. I offer a précis of this work and a brief summary of elective modernism before considering their relation. The view I set out suggests that elective modernism is a political philosophy and that although its use in relation to the use of scientific expertise in political and policy-making process has implications for the role of (bio)ethical expertise it does not, in the final analysis, provide an account that is appropriate for this latter form of specialist expertise. Nevertheless, it is an informative perspective, and one that can help us make sense of the political uses of (bio)ethical expertise
Neonatal Mortality Levels for 193 Countries in 2009 with Trends since 1990: A Systematic Analysis of Progress, Projections, and Priorities
Mikkel Oestergaard and colleagues develop annual estimates for neonatal mortality rates and neonatal deaths for 193 countries for 1990 to 2009, and forecasts into the future
- …