203 research outputs found
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Degradation of high concentrations of glycols, antifreeze, and deicing fluids
Preventing “a virological Hiroshima”: Cold War press coverage of biological weapons disarmament
This article examines representations of biological weapons during a crucial period in the recent history of this form of warfare. The study draws on a corpus of newspaper articles from the US New York Times and the UK Times and Guardian written around the time of the negotiation period of the 1972 Biological Weapons Convention, the international treaty banning this form of warfare. We argue that a conventional discourse can be found wherein biological weapons are portrayed as morally offensive, yet highly effective and militarily attractive. Interwoven with this discourse, however, is a secondary register which depicts biological weapons as ineffective, unpredictable and of questionable value for the military. We finish with a somewhat more speculative consideration of the significance of these discourses by asking what might have been at stake when journalists and other writers deployed such differing representations of biological warfare
Characterization of Clinically-Attenuated Burkholderia mallei by Whole Genome Sequencing: Candidate Strain for Exclusion from Select Agent Lists
is an understudied biothreat agent responsible for glanders which can be lethal in humans and animals. Research with this pathogen has been hampered in part by constraints of Select Agent regulations for safety reasons. Whole genomic sequencing (WGS) is an apt approach to characterize newly discovered or poorly understood microbial pathogens. genome. Therefore, the strain by itself is unlikely to revert naturally to its virulent phenotype. There were other genes present in one strain and not the other and vice-versa. was both avirulent in the natural host ponies, and did not possess T3SS associated genes may be fortuitous to advance biodefense research. The deleted virulence-essential T3SS is not likely to be re-acquired naturally. These findings may provide a basis for exclusion of SAVP1 from the Select Agent regulation or at least discussion of what else would be required for exclusion. This exclusion could accelerate research by investigators not possessing BSL-3 facilities and facilitate the production of reagents such as antibodies without the restraints of Select Agent regulation
Strengthening the BTWC
The role of the Biological and Toxin Weapons Convention in combating natural and deliberate disease outbreak
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