134 research outputs found
Letters from Wm. Chas. Roberts, J. B. Fisher, A. H. Throckmorton, Lucien Waggener, J. W. Logan, and A. B. Nelson
Letters of recommendation for O. W. Long
Defragmentation of in-vitro fertilization blastocyst stage embryos leading to rescued blastocyst expansion and clinical pregnancy
Embryo fragmentation, or extrusion of cell fragments, is a naturally occurring phenomenon that may be associated with impaired embryo development, failed implantation and decreased pregnancy rates. Previous studies have shown improvement in clinical outcomes after microsurgery to aspirate these cell fragments from embryos early during the embryo cleavage process. This case series of three patients with infertility showcases the successful application of the defragmentation technique in blastocyst stage embryos after in-vitro fertilization. The timing of defragmentation allows for better identification of those growth-arrested embryos that would benefit from “rescue� defragmentation. All three embryos demonstrated continued expansion and development after defragmentation, and resulted in clinical pregnancies.ECU Open Access Publishing Support Fun
Electrochemical activation and inhibition of neuromuscular systems through modulation of ion concentrations with ion-selective membranes
Conventional functional electrical stimulation aims to restore functional motor activity of patients with disabilities resulting from spinal cord injury or neurological disorders. However, intervention with functional electrical stimulation in neurological diseases lacks an effective implantable method that suppresses unwanted nerve signals. We have developed an electrochemical method to activate and inhibit a nerve by electrically modulating ion concentrations in situ along the nerve. Using ion-selective membranes to achieve different excitability states of the nerve, we observe either a reduction of the electrical threshold for stimulation by up to approximately 40%, or voluntary, reversible inhibition of nerve signal propagation. This low-threshold electrochemical stimulation method is applicable in current implantable neuroprosthetic devices, whereas the on-demand nerve-blocking mechanism could offer effective clinical intervention in disease states caused by uncontrolled nerve activation, such as epilepsy and chronic pain syndromes.Massachusetts Institute of Technology. Faculty Discretionary Research FundNational Institutes of Health (U.S.) (Award UL1 RR 025758)Harvard Catalyst (Grant
Chromatin tethering effects of hNopp140 are involved in the spatial organization of nucleolus and the rRNA gene transcription
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TELEMETRY NETWORKING USING ATM TECHNOLOGY
International Telemetering Conference Proceedings / October 25-28, 1993 / Riviera Hotel and Convention Center, Las Vegas, NevadaThe 1990's has been an era of integrating telemetry systems into networks. With the networking of telemetry systems, communications between systems is increasingly important. The telemetry system is no longer an isolated subsystem and the requirement for ubiquitous, distribution of telemetry data is also increasing. With declining DoD budgets, the cost of providing, not only, range-wide data distribution, but also, inter-range distribution is a major issue. Recent developments in commercial telecommunication data services may provide an answer to the range communications problems. In this paper, the use of Asynchronous transfer Mode (ATM) technology is examined as a means for transporting telemetry and other range data.International Foundation for TelemeteringProceedings from the International Telemetering Conference are made available by the International Foundation for Telemetering and the University of Arizona Libraries. Visit http://www.telemetry.org/index.php/contact-us if you have questions about items in this collection
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Atomic Energy Commission Report NYO-2974-1
From abstract: One of the principal purposes of the work reported was to study the stability of gas-solids suspensions in the presence of a thermal gradient. Previously reported experience with unstable suspensions is summarized
Produce Your Own Video Cases for Classroom Use: A Demonstration
"Video-recorded incidents and cases are very effective for focusing class discussion on specific concepts. They convey visual and emotional impacts that written cases cannot rival. Although video recordings are commercially available, it is difficult to find precisely what is needed to address the specific topics you may wish to teach. Most universities have video production facilities and technicians that can produce excellent quality video tapes. Drama departments usually have faculty members and students who are delighted to apply their talents to useful projects. An instructor can be the catalyst and coordinator that brings these resources together to produce interesting and effective classroom experiences for students. Wright State University has produced a series of video-recorded incidents and short cases about specific concepts in basic management This demonstration will show some of these and tell how they can be used to stimulate classroom discussion.
Evaluation of Gas-Graphite Suspensions as Nuclear Reactor Coolants. Final Report
ALL survey was made of experimental and theoretical work pertaining to the use of a suspension of graphite particles in a gas as a nuclear reactor coolant. Following a general review of the state-of-the-art and a detailed study of recent experimental data, it was concluded that present theoxy and experimental data are encouraging but inadequate as a basis for reactor design. Especially lacking are both theoretical and experimental work defining the hydrodynamic and thermal requirements for preventing the platingout of the solids from the suspension. Future work is recommended in which the stability of suspensions receives primary attention. Supporting parallel studies of basic theory, erosion, effects of nuclear radiations, and compatibility of materials, as well as development of specialized instrumentation and plant components, are also recommended. These would then be followed by experimental heat transfer and pressure drop studies to obtain correlations for reactor designm applications. (auth
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