Contribution to the pathology of spontaneous adiaspiromycosis in small mammals

A description is given of the pathological reaction of the lung tissue of small rodents and insectivores to spontaneous infection with the fungus Emmonsia crescens. No differences were observed in the reaction of the tissue of either the individual hosts or within the various seasons. These facts suggest that the origin of a granulomatous reaction to the presence of the adiaspore in small mammals may be a process associated with an early or still florid infection. In three cases, the authors observed verrucose proliferations on the outer layer of the adiaspore wall, and minute spherical bodies situated close to the mother adiaspore. In their opinion the phenomenon under consideration is the formation of daughter adiaspores (spherules). This finding is important because it may help in explaining of several lung changes.In A. flavicollis and A. sylvaticus from Bulgaria, the authors found granulomatous pneumonia and minute adiaspores which they believe to be adiaspores of the species Emmonsia parva